Ab initio wavefunctions in bioinorganic chemistry : more than a succes d'estime?
Permanent lenke
https://hdl.handle.net/10037/4086DOI
doi: 10.1007/s00775-011-0816-5Dato
2011Type
Journal articleTidsskriftartikkel
Peer reviewed
Forfatter
Ghosh, AbhikSammendrag
Dedicated to the memory of Björn Roos (1937–2010), one of the fathers of modern multiconfigurational quantum chemistry, who also cared deeply about chemical applications, and a fun and inspiring friend to countless theoretically oriented chemists.
Forlag
Springer VerlagSitering
Journal of Biological Inorganic Chemistry 16(2011) nr. 6 s. 819-820Metadata
Vis full innførselSamlinger
Følgende lisensfil er knyttet til denne innførselen:
Relaterte innførsler
Viser innførsler relatert til tittel, forfatter og emneord.
-
A Biofocussed Chemoprospecting Approach to Drug Discovery: Design, Synthesis and Bioactivity Screening of Diverse Biofocussed Chemical Libraries
Thakkar, Balmukund (Doctoral thesis; Doktorgradsavhandling, 2017-04-28)With pharma R & D witnessing rising cost, high attrition rates and an overall decline in productivity in recent times, newer approaches are needed for more efficient early phase drug discovery. This thesis describes a new approach, “biofocussed chemoprospecting”. The essence of the approach is to use diverse, yet “bio-like” compounds for efficient hit-finding, along with property filtering and ... -
Novel [18F]fluorinated prosthetic groups for the labelling of peptides for positron emission tyomography (PET)
Olberg, Dag Erlend (Doctoral thesis; Doktorgradsavhandling, 2009-11-20)Positron emission tomography is a non-invasive imaging modality allowing visualization and quantification of a wide variety of physiological and biochemical processes or of a specific lowdensity protein target. Some examples are blood flow, glucose consumption, fatty acid metabolism or detection and quantification of cell surface receptors in particular tissues. Within the spectrum of available ... -
Toward Tripeptidomimetic CXCR4 Antagonists: Design, Synthesis, Biological Evaluation, and Binding Mode Studies
Zachariassen, Zack George (Doctoral thesis; Doktorgradsavhandling, 2014-04-11)In order for the HIV virus to take over and destroy human immune cells, which results in AIDS, the virus first has to enter the cells. This takes place by interactions between viral proteins and specific receptors on the surface of our cells. One of these receptors is CXCR4, and it has been shown that chemical compounds that bind to and block the CXCR4 receptor, so-called CXCR4 antagonists, are able ...