Blar i tittel Doktorgradsavhandlinger (BFE-fak)

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    • Å temme torsken – fremveksten av norsk torskeoppdrettsnæring. En beretning om kollektivt entreprenørskap 

      Enoksen, Ken Harald (Doctoral thesis; Doktorgradsavhandling, 2018-03-19)
      Det overordnede tema for avhandlingen er fremveksten av nye næringer. Gjennom å analysere historien om norsk torskeoppdrett, fra de første ideer om torskeoppdrett oppstod frem til etableringen av verdens første børsnoterte torskeoppdrettsselskap - Codfarmers med tickeren "COD" på Oslo børs – bidrar avhandlingen med ny kunnskap til det «kunnskaps-hullet» som eksisterer innenfor feltet nye/gryende ...

    • Bacterial flagellin : a novel adjuvant for vaccine strategies 

      Hynes, Natasha (Doctoral thesis; Doktorgradsavhandling, 2011-10-18)
      Flagellin is the principal structural protein in the locomotive organ flagellum present on flagellated bacteria, and is known to be an important evolutionarily conserved PAMP. Flagellin has been shown to bind to the PRR TLR5 which induces innate immune system responses and signaling pathways. In mammals, much focus has been placed on this protein in vaccine studies for its possible function as an ...

    • Bioactive secondary metabolites from bacteria. Natural products from marine and terrestrial bacteria, dereplication, isolation and investigation of bacterial secondary metabolites 

      Schneider, Yannik Karl-Heinz (Doctoral thesis; Doktorgradsavhandling, 2020-09-29)
      The thesis gives an introduction to natural product drug discovery and the underlying chemical principles that make natural products privileged structures for drug discovery. Paper I deals with the isolation of Lipid 430 from cultures of two <i>Algibacter</i> sp. isolates and the investigation of their anti-proliferative and anti-bacterial effect. Paper II describes the isolation of Serratiochelin ...

    • "Bioactivity profile of barettin - With special focus on anti-inflammatory, antioxidant and anticoagulant activities" 

      Lind, Karianne Fredenfeldt (Doctoral thesis; Doktorgradsavhandling, 2015-04-17)
      The diversity of the marine species inhabiting the oceans makes them highly interesting as potential sources of bioactive molecules for various applications. The extreme environment in the Barents Sea, in terms of temperature and light availability, have forced its organisms to adapt to their surroundings by developing unique biomolecules, and Arctic marine organisms are therefore an excellent ...

    • Bioactivity profiling and mode of action studies of antibacterial and antibiofilm agents of marine origin 

      Rahman, Ataur (Doctoral thesis; Doktorgradsavhandling, 2024-01-26)
      <p>The emergence of drug-resistant strains and new pathogens intensifies the need for new antimicrobials. Additionally, bacterial biofilms, which contribute to persistent infections, further complicate treatment efforts. The increasing difficulty in discovering and developing new antimicrobials adds to this challenge. However, marine environments, with their vast biodiversity, offer a promising ...

    • A bioeconomic perspective on the Barents Sea snow crab (Chionoecetes opilio, Majidae) fishery 

      Hogrenning, Egil (Doctoral thesis; Doktorgradsavhandling, 2023-11-30)
      The focus of this thesis is the Barents Sea snow crab (<i>Chionoecetes opilio</i>, Majidae) fishery. The crab was first observed in the area in 1996, and a fishery for the crab commenced in 2012. Both the crab population and the fishery are still expanding. The main objective of this thesis is to develop research that contributes to an improved utilization of the crab. For this purpose, a spatial ...

    • A bioeconomic perspective on the Norwegian Barents Sea cod fishery 

      Eide, Arne (Doctoral thesis; Doktorgradsavhandling, 2008-11-14)

    • Bioprospecting of Arctic marine microorganisms. Exploring microbial secondary metabolite production using the one strain-many compounds approach: isolation and characterization of secondary metabolites 

      Kristoffersen, Venke (Doctoral thesis; Doktorgradsavhandling, 2021-12-20)
      <p>Natural products have been used by humans since ancient times as benefactors for improved health. Prior to modern medicine and chemistry, these compounds remained hidden in the plants, animals and other organisms used to heal inflammation, wounds, headache and stomachache among other conditions. Since the start of modern drug discovery with isolation of morphine in 1805, numerous natural products ...

    • Bioprospecting of Arctic marine organisms Employing bioassay-, chemistry-, and metabolomics-guided isolation 

      Olsen, Elisabeth Klungerbo (Doctoral thesis; Doktorgradsavhandling, 2015-09-25)
      The marine environment inhabits a large diversity of organisms that produce natural products as a strategy for survival. Many marine natural products are found to display different bioactivities and some of them have reached the market as drugs or dietary supplements. Comprehending the great potential of bioactive marine natural products motivates for the continuing bioprospecting of organisms from ...

    • Bioprospecting of marine fungi from the High Arctic: A study of high latitude marine fungi from understudied taxa; bioactivity potential, taxonomy and genomics 

      Hagestad, Ole Christian (Doctoral thesis; Doktorgradsavhandling, 2021-06-17)
      Marine fungi comprise a group of organisms that have been overlooked for a long time. Research interest has increased with the realization of the important ecological role and rich chemistry of marine fungi. Marine fungi have yielded thousands of new natural products the last decade, but many taxa remain unstudied. Marine fungi from the Arctic have not been reported in literature in regard to ...

    • Bioprospecting of marine microorganisms for the discovery of antibacterial compounds - Isolation, structure elucidation and bioactivity assessment of marine microbial natural products 

      Jenssen, Marte (Doctoral thesis; Doktorgradsavhandling, 2022-04-27)
      <p>Infectious diseases have been a problem for humans since the beginning of human existence. The “golden age” of antibiotics started at the end of the 1920s, with the discovery of penicillin by Sir Alexander Fleming. This was followed by the discovery of several life-saving antibiotics. The number of new marketed antibiotics has declined, and most pharmaceutical companies are no longer working in ...

    • Bioprospecting of marine phytoplankton from large scale cultivation - Effect of culture conditions on bioactivity and biochemistry of the diatom Porosira glacialis 

      Osvik, Renate Døving (Doctoral thesis; Doktorgradsavhandling, 2021-06-23)
      The diatoms make up the largest and most important group of marine microalgae. They are responsible for a quarter of all inorganic carbon fixation in the ocean and are thus of immense importance for global CO2 sequestration. This makes them good candidates for biological carbon capture and utilization (CCU) by mass cultivation using CO2 emissions from industrial point sources. Large scale cultivation ...

    • Bivalves as indicators of environmental perturbations related to climate and ocean acidification 

      Vihtakari, Mikko (Doctoral thesis; Doktorgradsavhandling, 2015-03-13)
      The aims of this thesis were to increase knowledge on 1) susceptibility of bivalves to environmental perturbations and 2) usage of bivalve shells as sub-annual environmental proxy archives. These objectives were addressed using two experimental settings: 1) an ocean acidification (OA) experiment on bivalve gametes and early larval stages, and 2) year-long bivalve deployments on oceanographic moorings ...

    • Boundary construction in mandated science : the case of ICES' advice on fisheries management 

      Nolde Nielsen, Kåre (Doctoral thesis; Doktorgradsavhandling, 2008-11-21)
      What is the relationship between science and politics? What should it be? How are their respective roles conceived and acted out in practice? Should science and politics be clearly separated? How? Are there cases in which they can be usefully mixed? What cases are those, and are there some ways of mixing that are better than others? This project explores such questions by examining relationships ...

    • Breathtaking brains Intrinsic neural adaptations to hypoxia 

      Geiseler, Samuel (Doctoral thesis; Doktorgradsavhandling, 2016-04-07)
      To maintain and restore the membrane potential that is crucial for normal function of neurons, the brain requires a constant and high energy supply. This supply is mainly covered by oxidative metabolism. When oxygen supply is impaired on a cellular level (hypoxia), such as in the case of stroke, neural energy levels become inadequate to maintain ion balance, leading to excessive ion flux and ultimately ...

    • Bureaucrats and Boundaries. The changing intersection between experts, local communities and environmental administration in nature protection 

      Bay-Larsen, Ingrid Agathe (Doctoral thesis; Doktorgradsavhandling, 2013-03-08)
      Loss of biodiversity and fragmentation of habitats are two of the world’s persistent environmental problems. This is due to the emerging complexities, uncertainties and questions of societal scale in both defining and resolving the problems. One of the challenges connected to resolving these problems pertains to the divide between the local level, which carries the costs of restrictions and regulations ...

    • Buyer-seller relationships across cultures: Conceptual, empirical and methodological issues 

      Voldnes, Gøril (Doctoral thesis; Doktorgradsavhandling, 2015-01-22)
      The aim of this dissertation was to examine the factors important in achieving success in cross-cultural business relationships, in this case between Russian buyers and Norwegian sellers of seafood. Emphasis was placed on exploring how cultural differences influence factors important in relationship satisfaction, how to attain the various factors, and how cultural differences are managed by buyers ...

    • Bycatch reduction and alternative exploitation patterns in demersal trawl fisheries of the Baltic Sea and the North Sea 

      Santos, Juan (Doctoral thesis; Doktorgradsavhandling, 2021-12-17)
      <p>In the Baltic Sea and North Sea, the sustainability of bottom-trawl fisheries is threatened by many issues, such as the impact of climate change on exploited demersal stocks, long-term overfishing, and the European Landing Obligation for quoted species. This thesis identifies challenges to bycatch and harvesting patterns of targeted species in four relevant Baltic Sea and North Sea bottom-trawl ...

    • Bycatch Reduction in Eastern North Pacific Trawl Fisheries 

      Lomeli, Mark Joseph Max (Doctoral thesis; Doktorgradsavhandling, 2019-12-20)
      <p>This thesis provides an overview of recent selectivity studies conducted in eastern North Pacific trawl fisheries (e.g., West Coast groundfish bottom trawl fishery, Pacific hake [<i>Merluccius productus</i>] fishery, and ocean shrimp [<i>Pandalus jordani</i>] fishery). Collectively, these fisheries play a significant role in supporting fishing jobs, income, and coastal communities. However, bycatch ...

    • Calanus glacialis : the role of lipids in the life cycle and for the Arctic pelagic food web 

      Wold, Anette (Doctoral thesis; Doktorgradsavhandling, 2012-05-23)
      The Arctic marine ecosystem is characterized by strong seasonality and a short but productive period of primary production in the spring when the ice breaks up. Calanus glacialis is one of the key links between primary producers and higher trophic levels, and it is adapted to the strong seasonality by life cycle traits such as; seasonal vertical migration, diapausing, reproduction in the spring and ...