Background: Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer’s disease (AD) and can be measured by segmentation of magnetic resonance images (MRI). Objective: To assess the clinical utility of automated volumetry in a cognitively well-defined and biomarker-classified multi-center longitudinal predementia cohort. <p>Methods: We used Automatic Segmentation of ...

In their lead article, Klug et al. conceptualize job insecurity as a multilevel construct whereby individuals are situated in meso- and macro-level contexts. Their resulting model highlights that the experience of job insecurity, as well as reactions to job insecurity, are not only affected by factors emanating from individuals' direct environment (i.e., at the individual level) but also from different ...

Excessive consumption of highly palatable foods rich in sugar and fat, often referred to as “junk” or “fast” foods, plays a central role in the development of obesity. The highly palatable characteristics of these foods activate hedonic and motivational mechanisms to promote food-seeking behavior and overeating, which is largely regulated by the brain reward system. Excessive junk food consumption ...

Bakgrunn: Flyt er et livsmestringsprogram for elever på 10. trinn som har til hensikt å gjøre deltakere bedre rustet til å gjennomføre videregående skole. Programmet er et styrkebasert gruppetiltak for ungdom i risiko for å droppe ut fra videregående, men ungdom uten kjent risiko inkluderes også. For elever omfatter tiltaket totalt 80 timer med organiserte aktiviteter fordelt på helg- og kveldssamlinger ...

Motivation can be described as the processes that activate, direct, and determine the persistence of goal-directed behavior. A certain level of sexual motivation is required to activate approach behavior which could potentially lead to copulation and reproduction. Here, we discuss the use of the sexual incentive motivation test to assess the magnitude of sexual motivation in rodents in response to ...

Decades of research have greatly improved our understanding of intrinsic human brain organization in terms of functional networks and the transmodal hubs within the cortex at which they converge. However, substrates of multinetwork integration in the human subcortex are relatively uncharted. Here, we leveraged recent advances in subcortical atlasing and ultra-high field (7 T) imaging optimized for ...

Bakgrunn: Denne artikkelen er en kunnskapsoppsummering og klassifisering av tiltaket Cool Kids, et program med hovedmålsetting å hjelpe barn og unge i alderen 6-18 år å håndtere angst og relaterte vansker. Programmet kan tilbys både individuelt og i gruppeformat, med ca. 10 møter. Cool Kids -programmet er teoretisk forankret i kognitiv adferdsterapi. Sentrale metoder i programmet omfatter psykoedukasjon, ...

Background: The association between SHA and negative mental health increases the need to understand risk factors for SHA victimization, which is important for future development of prevention programs.<p> <p>Objective: To examine which combinations of demographic- and mental health factors were associated with subsequent SHA victimization, and the prevalence of elite athletes, recreational athletes, ...

Background - Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal clinical studies that include biomarker negative healthy controls and cases with established AD pathology. Here, we employ longitudinally sampled cerebrospinal fluid (CSF) core AD, ...

Individuals with physical and mental disabilities can be stigmatized and perceived in terms of their disabilities in the public domain. This is less pervasive in the private domain, because of the presence of individuating information. We argue that disabilities decrease individuals’ everyday opportunities to receive basic equality-based respect experiences in the public domain and thus makes it ...