English
norskMastergradsoppgaver i farmasi
Vis alle innførsler i samlingen sortert på
Nye registreringer
-
Associations between use of antibiotic and non-antibiotic drugs on the gastrointestinal carriage of Klebsiella pneumoniae in a general adult population in Norway
(Master thesis; Mastergradsoppgave, 2021-11-14)Antimicrobial resistance has long been a problem and a struggle to compromise as life-threatening infections are harder to treat. Among common pathogens, Klebsiella pneumoniae (K.pneumoniae) can be a highly resistant bacteria associated with increased mortality when infecting critically ill and immunocompromised patients. Prevalence of gastrointestinal carriage depends on several risk factors. ... -
Using real world data for pharmacoeconomic assessments - a case study
(Mastergradsoppgave; Master thesis, 2024-05-14)Pembrolizumab monotherapy for non-small cell lung cancer (NSCLC) was deemed not cost-effective due to limited data, high uncertainty regarding long term results and a considerable budget impact. However, due to confidential price agreements it was approved in 2017, as first-line treatment for metastatic NSCLC that expresses PD-L1 ≥ 50 %. Given potential discrepancies between clinical efficacy and ... -
Isolation and Biological Evaluation of Phomenins from the Marine Fungus Parafenestella sp.
(Mastergradsoppgave; Master thesis, 2024-05-15)Background: Marine fungi are prolific producers of secondary metabolites. Phomenin A (2) and B (3) are secondary metabolites produced by Parafenestella sp. Previous studies have described them as bioactive, but due to the limited availability of pure compounds, their bioactivity has yet to be extensively characterised. These compounds were identified and isolated at Marbio, but the quantities obtained ... -
Mass cultivation of the marine diatom Porosira glacialis: Method development and comparison of pigment composition in response to irradiance wavelenght
(Master thesis; Mastergradsoppgave, 2022-05-19)In 2015, UiT The Arctic University of Norway and a local smelting plant initiated a project aiming to reduce the carbon footprint by mass cultivation of microalgae. The ability of the microalgae to directly capture industrially emitted CO2 and utilize wastewater as alternative nutrient sources to produce high value biomass, causes the bio-carbon recycling to represent both an environmental and ... -
Identification and semi-quantitative analysis of lipids in the diatom Porosira glacialis
(Mastergradsoppgave; Master thesis, 2022-05-18)Background: In 2015, The University of Tromsø initiated a project with local industry involving cultivation of marine microalgae to reduce industrial CO2-emissions. Marine microalgae are primary producers with high capacity for carbon fixation into biomass rich in lipids. Their lipid composition is characterized by high content of PUFAs such as EPA (20:5) and DHA (22:6). The biomass can potentially ... -
Ordningen «reseptfri medisin med veiledning» med fokus på Viagra Reseptfri® - farmasøyters erfaringer, og tanker rundt videreutvikling av ordningen
(Mastergradsoppgave; Master thesis, 2021-05-18)Bakgrunn: Apotekbransjen og farmasøytrollen er stadig i endring, og i de siste årene har flere og flere farmasøytiske tjenester blitt implementert i apotek. Dette har ført til større fokus på legemiddelveiledning og formidling av legemiddelinformasjon, samt apotek som et lavterskeltilbud innen helse. I 2018 åpnet Stortinget for å fjerne reseptplikten på enkelte legemidler, slik at de kunne selges ... -
The effect of β-lactamase evolution on biofilm formation in Vibrio cholerae
(Master thesis; Mastergradsoppgave, 2023-05-15)Antimicrobial resistance (AMR) has emerged as one of the greatest threats to public health in the 21st century. Especially, the production of -lactamase enzymes has become the leading cause of -lactam resistance in Gram-negative pathogens. In addition, many of the pathogens associated with extensive antimicrobial resistance form biofilms, which further increases their persistence. Studies from ... -
Kvalitet av legemiddelbruk og legemiddelinformasjon hos hoftebruddspasienter ved Sykehuset i Vestfold HF – en tverrsnittstudie
(Master thesis; Mastergradsoppgave, 2019-05-15)Det er i hovedsak eldre personer som gjennomgår hoftebrudd, som er et fryktet osteoporotisk brudd. Eldre har flere sykdommer som fører til at de blir behandlet med flere legemidler sammenlignet med yngre. Dette vil igjen øke risikoen for uhensiktsmessig legemiddelbruk. I tillegg overføres eldre hyppig inn og ut og mellom helseinstitusjoner, som skaper et behov for velfungerende informasjonsoverføring. ... -
Dual delivery of chlorogenic acid and mimic of antimicrobial peptide – towards wound treatment
(Master thesis; Mastergradsoppgave, 2022-05-12)Chronic wounds are a major burden, causing both morbidity and mortality in patients, as well as a massive economical strain on health care systems worldwide. These wounds have a high degree of complexity and are often difficult to treat due to the many factors limiting healing, such as inflammation, biofilm formation and bacterial infections. With these typically persistent infections and a rising ... -
Chitosan-modified liposomes for delivery of membrane-active antimicrobials – exploring the role of the polymer
(Master thesis; Mastergradsoppgave, 2022-05-12)Antimicrobial resistance in skin injury infections is becoming a rising problem as more conventional antimicrobials become ineffective in resistant infections. Therefore, developing novel effective antimicrobials while promoting wound healing is urgently needed. Membrane-active antimicrobials, such as antimicrobial peptides (AMPs), display promising antimicrobial activity, and could potentially solve ... -
Using High-Resolution Mass Spectrometry to identify lipids in marine bacterial biomass
(Mastergradsoppgave; Master thesis, 2023-05-14)Background: BMFishfeed is a cooperative project since 2021 between UiT the Arctic University of Norway, NORCE Stavanger and the University of South-Eastern Norway where the goal is to develop a lipid-rich bacterial meal that can be utilized as fish feed in the aquaculture industry. Carbon-rich waste from an omega-3 production site is used as nutrition for marine bacterial cultures, which are fermented ... -
Process optimization of albumin-stabilized mitotane nanoparticle preparation by dual centrifugation and first lyophilization study
(Mastergradsoppgave; Master thesis, 2022-05-13)Albumin-stabilized mitotane nanoparticles intended for intravenous application can serve as a potential formulation for the treatment of adrenocortical carcinoma. However, the particle size of a nanoparticle-based formulation is crucial for the in vivo behavior of the nanoparticles following an intravenous injection. Prior to this project, the particle size of this nanoformulation had a mean of ... -
Push and pull factors for migration of foreign pharmacists to Norway
(Mastergradsoppgave; Master thesis, 2022-05-12)Migration of foreign pharmacists to Norway has increased considerably in recent years. Data from the Directorate of Health shows that 1592 foreign pharmacists received authorization in Norway from 2013 to 2021 as compared to 1952 Norwegian pharmacists. There are several theories of migration, but “push and pull theory” is the most widely used approach to learn about reasons of migration. According ... -
Computational studies on the human GnRH-I and the GnRH-receptor
(Mastergradsoppgave; Master thesis, 2022-05-12)Gonadotropin-releasing hormone receptor (GnRH-R), which is a Class A G-protein coupled receptor (GPCR), has a vital role in the regulation of sex hormones. The receptor also has a prominent role in diseases, with examples being reproductive cancers and non-reproductive cancers like glioblastoma. Gonadotropin-releasing hormone (GnRH) agonists have been proven to combat cell proliferation in cancers. ... -
The productivity gain by preventing first and subsequent hip fractures in osteoporotic patients as a result of optimal treatment
(Mastergradsoppgave; Master thesis, 2022-05-11)Background: Preventing hip fractures could prevent patient disability and premature death, and lead to substantial societal savings in terms of productivity gains. However, the Norwegian government has decided against emphasizing productivity gains in prioritization decisions for financing pharmaceutical drugs. The question, however, remains whether including productivity gains could lead to better ... -
Medicine articles on English Wikipedia: Quantifying the presence of pharmaceutical industry edits and analyzing their content.
(Mastergradsoppgave; Master thesis, 2022-05-11)Today, Wikipedia has developed into a prominent source for health queries to the vast public. Over the years, some studies have been performed to understand what the webpage can and cannot offer. However, the current literature lacks knowledge of how the pharmaceutical industry is present in Wikipedia’s medicine articles. The immediate objective of this research was to quantify the presence of ... -
Development of DNA Nanoparticles with Properties for Enhanced Biofilm Uptake
(Mastergradsoppgave; Master thesis, 2022-05-11)Microbial biofilms account for up to 80% of all bacterial infections. They are described as small structural communities of bacteria which are embedded in a self-produced extracellular (EPS) matrix. This EPS matrix poses a substantial challenge for antimicrobial treatment by hindering traversal of antimicrobial agents. Nanotechnology based drug delivery systems (DDS) offer a promising solution ... -
Hvilke tanker og erfaringer har leger rundt korrekt legemiddelliste og legemiddelbruk til pasienter i akuttmottak? Og hvordan ser de for seg et fremtidig samarbeid med farmasøyt?
(Mastergradsoppgave; Master thesis, 2020-08-01)BAKGRUNN: Legemiddelfeil er et utbredt problem både internasjonalt og nasjonalt, dette kan medfører risiko for pasientsikkerheten. Kliniske farmasøyter er bedre til å oppdage potensielt klinisk relevante uoverensstemmelser enn leger og er blitt mer utbredt på sykehus. De er foreløpig er ikke vanlig på akuttmottak i Norge i motsetning til i andre land. FORMÅL: Formålet med studien er å undersøke ... -
Fall hos ortopediske pasienter – sammenligning av to fallscreeningverktøy
(Master thesis; Mastergradsoppgave, 2022-05-12)Bakgrunn og formål: Fall er en av de vanligste rapportere uheldige hendelsene på sykehus. Fall medfører betydelige konsekvenser for pasienten og samfunnet. Fallforebyggende tiltak, som screeningverktøy, er utviklet for å identifisere pasienter med fallrisiko. Hensikten med studien var å sammenligne effekten av screeningverktøyene Downton Fall Risk Index (Downton) og Pasientsikkerhetsprogrammets ... -
Prisforhandling for nye legemidler i spesialisthelsetjenesten Er det sammenheng mellom fremforhandlet rabatt og prisforhandlingstid?
(Mastergradsoppgave; Master thesis, 2022-05-16)Bakgrunn: Kostnadseffektive legemidler er en forutsetning for offentlig finansiering av nye legemidler til bruk i spesialisthelsetjenesten i Norge. Prisforhandling med leverandørselskapene utføres av Sykehusinnkjøp HF på vegne av de regionale helseforetakene. I en prisforhandling tilbyr leverandørene en konfidensiell tilbudspris, og dersom den ikke regnes som kostnadseffektiv kan det resultere i at ...
RSS 1.0