Now showing items 1281-1300 of 1850

    • Uric acid predicts mortality and ischaemic stroke in subjects with diastolic dysfunction: the Tromsø Study 1994-2013 

      Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Storhaug, Hilde-Merete; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Wilsgaard, Tom; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-31)
      Aims: To investigate whether serum uric acid predicts adverse outcomes in persons with indices of diastolic dysfunction in a general population. <br>Methods and results: We performed a prospective cohort study among 1460 women and 1480 men from 1994 to 2013. End- points were all-cause mortality, incident myocardial infarction, and incident ischaemic stroke. We strati fi ed the analyses ...
    • Knowledge about preventive dentistry versus self-reported competence in providing preventive oral healthcare – a study among Nepalese dentists 

      Wagle, Madhu; Acharya, Ganesh; Basnet, Purusotam; Trovik, Tordis A (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-12)
      Background: Dentists ’ and dental healthcare providers ’ professional knowledge and attitude towards the prevention of oral diseases may have an impact on the oral health of the general population. The aim of this study was to describe Nepalese dentists ’ competency in giving preventive education and treatment to their patients, and to assess their level of knowledge about preventive dental ...
    • Randomized phase II trial comparing twice daily hyperfractionated with once daily hypofractionated thoracic radiotherapy in limited disease small cell lung cancer 

      Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien; Fløtten, Øystein; Brustugun, Odd Terje; Brunsvig, Paal Fr.; Aasebø, Ulf; Bremnes, Roy M.; Tollåli, Terje; Hornslien, Kjersti; Aksnessæther, Bjørg Y.; Liaaen, Erik Dyb; Sundstrøm, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-23)
      <br>BACKGROUND: <br> Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small cell lung cancer (LD SCLC). Twice daily TRT is well documented, but not universally implemented - probably mainly due to inconvenience and concerns about toxicity. A schedule of three-week hypofractionated TRT is a commonly used alternative. This is the first randomized trial ...
    • Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity 

      de Oliveira, Caio Fernando; Cavanagh, Jorunn Pauline; Fredheim, Elizabeth G Aarag; Reiter, Keli Cristine; Rieger, Alexandre; Klingenberg, Claus; D'Azevedo, Pedro Alves; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05)
      Introduction: Coagulase-negative staphylococci (CoNS) are the most prevalent pathogens in nosocomial infections and may serve as a reservoir of mobile genetic elements such as the staphylococcal cassette chromosome mec (SCCmec) encoding methicillin resistance. Molecular characterization of SCCmec types combined with advanced molecular typing techniques may provide essential information for ...
    • Dissection of the internal carotid artery and stroke after mandibular fractures: a case report and review of the literature 

      Tveita, Ingrid Aune; Madsen, Martin Ragnar Skjerve; Nielsen, Erik Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-02)
      Background: We present a report of a patient with blunt trauma and mandibular fractures who developed a significant cerebral infarction due to an initially unrecognized injury of her left internal carotid artery. We believe that increased knowledge of this association will facilitate early recognition and hence prevention of a devastating outcome. <br>Case presentation: A 41-year-old ethnic ...
    • Geographical accessibility and duration of untreated psychosis: Distance as a determinant of treatment delay 

      Kvig, Erling Inge; Brinchmann, Beate; Moe, Cathrine Fredriksen; Nilssen, Steinar; Larsen, Tor Ketil; Sørgaard, Knut W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-10)
      Background: The duration of untreated psychosis is determined by both patient and service related factors. Few studies have considered the geographical accessibility of services in relation to treatment delay in early psychosis. To address this, we investigated whether treatment delay is co-determined by straight-line distance to hospital based specialist services in a mainly rural mental health ...
    • Clinical validation of a new “call-out algorithm” for postoperative pain management: a two-center prospective randomized trial 

      Kuklin, Vladimir; Dybvik, Lisa; Skraastad, Erlend Johan; Yeltayeva, Aigerim; Konkayev, Aidos; Musaeva, Tatiana; Zabolotskikh, Igor; Bjertnaes, Lars J.; Dahl, Vegard; Ræder, Johan (Conference object; Konferansebidrag, 2017-05-06)
      The goal of modern postoperative pain management is to relieve pain while keeping side effects to a minimum. Still, in recent investigations, between 20% and 40% of all postoperative patients report high levels of pain after surgery, while 20-30% experience adverse effects of opioid analgetics [1,2]. In a study, in which the hospitals had introduced pain management guided by the patients' own ...
    • Effects of morphine or ketamine in rats with asphyxial cardiac arrest: a pilot study 

      Kuklin, Vladimir; Kondratyev, Timofey; Konkayeva, Maya; Akhatov, Nurlan; Sovershaev, Mikhail; Konkayev, Aidos; Tveita, Torkjel (Conference object; Konferansebidrag, 2017-05-06)
      Acute hypoxia results in uncontrolled release of glutamate and the consequent stimulation of N-methyl-D-aspartate (NMDA) receptors, which affects the whole ionic homeostasis and finally activates apoptosis of neurons. A potential therapeutic approach to prevent this sequence of events is a blockade of NMDA receptors. Meanwhile, in different models of acute hypoxia, activation of delta-opioid ...
    • Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases 

      Hinks, A; Bowes, J; Cobb, J; Ainsworth, HC; Marion, MC; Comeau, ME; Sudman, M; Han, B; Becker, ML; Bohnsack, JF; de Bakker, PIW; Haas, JP; Hazen, M; Lovell, DJ; Nigrovic, PA; Nordal, Ellen Berit; Punnaro, M; Rosenberg, AM; Rygg, Marite; Smith, S.L.; Wise, CA; Videm, Vibeke; Wedderburn, LR; Yarwood, A; Yeung, RSM; Prahalad, S; Langefeld, CD; Raychaudhuri, S; Thompson, SD; Thomson, W (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-20)
      Objectives: Juvenile idiopathic arthritis ( JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification system. The human leucocyte antigen (HLA) region is strongly associated with JIA. Fine-mapping of the region was performed to look for similarities and differences in ...
    • Incidence and predictors of Uveitis in juvenile idiopathic arthritis in a Nordic long-term cohort study. 

      Nordal, Ellen Berit; Rypdal, Veronika Gjertsen; Christoffersen, Terje; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Nielsen, Susan; Peltoniemi, Suvi; Straume, Bjørn; Zak, Marek S.; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-18)
      Background: The incidence of uveitis associated with juvenile idiopathic arthritis (JIA) varies around the world. Our aim was to investigate the incidence and predictors of uveitis in a Nordic population-based cohort. <br>Methods: Consecutive JIA cases from defined geographical areas in Denmark, Finland, Sweden and Norway with disease onset between January 1997 to June 2000 were followed for ...
    • How mental health service systems are organized may affect the rate of acute admissions to specialized care: Report from a natural experiment involving 5338 admissions 

      Myklebust, Lars Henrik Ryther; Sørgaard, Knut W.; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-10)
      Objectives: Studies on the dynamics between service organization and acute admissions to psychiatric specialized care have given ambiguous results. We studied the effect of several variables, including service organization, coercion, and patient characteristics on the rate of acute admissions to psychiatric specialist services. In a natural experiment-like study in Norway, we compared a ...
    • The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort 

      Ness, Nora; Andersen, Sigve; Khanehkenari, Mehrdad Rakaee; Nordbakken, Cecilie V.; Valkov, Andre; Paulsen, Erna-Elise; Nordby, Yngve; Bremnes, Roy M.; Dønnem, Tom; Busund, Lill-Tove; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-01)
      Programmed cell death protein 1 (PD-1) and its ligand Programmed death ligand 1 (PD-L1) have gained massive attention in cancer research due to recent availability and their targeted antitumor effects. Their role in prostate cancer is still undetermined. We constructed tissue microarrays from prostatectomy specimens from 535 prostate cancer patients. Following validation of antibodies, ...
    • Growing up with chronic arthritis: the confusing matter of classification 

      Nordal, Ellen Berit; Guillaume-Czitrom, Severine; Sibilia, Jean (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-09)
      Disease classification in rheumatology is a matter of debate, in paediatrics between International League Against Rheumatism (ILAR) classification ‘pros and cons’, as well as between paediatric and adult rheumatologists. Indeed, there is no consensus yet about how we should name the disease of adults with juvenile idiopathic arthritis (JIA) in childhood. The non-concordance of adult and paediatric ...
    • mHealth technologies for chronic disease prevention and management 

      Laranjo, Liliana; Lau, Annie Y.S.; Oldenburg, B.; Gabarron, Elia; O'Neill, A.; Chan, S.; Coiera, E. (Research report; Forskningsrapport, 2015-12)
      Aims and background: The aim of this rapid review is to examine the evidence relating to the benefits, uptake and operationalisation of mHealth technologies for chronic disease management and prevention. In a context of rapidly emerging technologies, it is important to understand what evidence is available to inform policy interventions designed to integrate technology for health service delivery, ...
    • Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci 

      Cavanagh, Jorunn Pauline; Wolden, Runa; Heise, Philipp; Esaiassen, Eirin; Klingenberg, Claus; Aarag, Elizabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-07)
      The primary aim of this study was to determine antimicrobial resistance in coagulase-negative staphylococci (CoNS) from healthy adults in the community. Healthy adults (n = 114) were swabbed on six body sites; both armpits, both knee pits and both sides of the groin. Species determination was performed using Matrix Assisted Laser Desorption Ionization – Time of Flight (MALDI-TOF) and susceptibility ...
    • Elevated blood pressure is not associated with accelerated glomerular filtration rate decline in the general non-diabetic middle-aged population 

      Eriksen, Bjørn Odvar; Stefansson, Vidar Tor Nyborg; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Schei, Jørgen; Solbu, Marit Dahl; Wilsgaard, Tom; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-14)
      Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated blood pressure (BP) was associated with accelerated GFR decline in the general population. The study ...
    • Perforator-guided drug injection at the point of nerve entrapment 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-14)
      Letter to the Editor
    • Perforator-guided drug injection in the treatment of abdominal wall pain 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-25)
      Background. Pain from the abdominal wall can be caused by nerve entrapment, a condition called abdominal cutaneous nerve entrapment syndrome (ACNES). As an alternative to surgery, ACNES may be treated with injection of local anesthetics, corticosteroids, or botulinum toxin at the point of maximal pain. Method. The point of maximal pain was marked on the abdominal skin. Using color Doppler ultrasound, ...
    • Reply: Form Stability of the Style 410 Implant: Definitions, Conjectures, and the Rest of the Story 

      Weum, Sven Magne; Weerd, Louis de; Kristiansen, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
    • The Sensate Medial Dorsal Intercostal Artery Perforator Flap as an Option for Treatment of Dorsal Cervicothoracic Midline Defects 

      Weum, Sven Magne; De Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Letter to the Editor