Now showing items 801-820 of 1850

    • Prevalence of temporomandibular disorder in children and adolescents with juvenile idiopathic arthritis – a Norwegian cross- sectional multicentre study 

      Fischer, Johannes Maria; Skeie, Marit Slåttelid; Rosendahl, Karen; Tylleskär, Karin; Lie, Stein Atle; Shi, Xie-Qi; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet; Halbig, Josefine Mareile; Marti, Larissa von Wangenheim; Rygg, Marite; Frid, Paula; Stoustrup, Peter; Rosén, Annika (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-13)
      <i>Background</i> - Children and adolescents with juvenile idiopathic arthritis (JIA) may suffer pain from temporomandibular disorder (TMD). Still, routines for the assessment of temporomandibular joint (TMJ) pain in health and dental care are lacking. The aims of this study were to examine the prevalence of TMD in children and adolescents with JIA compared to their healthy peers and to investigate ...
    • Whole-body magnetic resonance imaging in children – how and why? A systematic review 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Lein, Regina Küfner; Rosendahl, Karen; Avenarius, Derk; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
      Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free ...
    • Qualitative Evaluations of mHealth Interventions: Current Gaps and Future Directions 

      Bradway, Meghan; Leibowitz, Kari; Garrison, Kathleen A.; Howe, Lauren; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Psycho-social factors are often addressed in behavioral health studies. While the purpose of many mHealth interventions is to facilitate behavior change, the focus is more prominently on the functionality and usability of the technology and less on the psycho-social factors that contribute to behavior change. Here we aim to identify the extent to which mHealth interventions for patient self- management ...
    • Levels of mental distress over 18 years after entering treatment for substance use disorders: A longitudinal cohort study 

      Hjemsæter, Arne Jan; Bramness, Jørgen Gustav; Drake, Robert; Skeie, Ivar; Monsbakken, Bent Berntsen; Saltyte Benth, Jurate; Landheim, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-17)
      <i>Aims:</i> The aims were to investigate whether baseline characteristics and problematic substance use were related to change in mental distress over time in patients with substance use disorders during an 18-year period.<p> <p><i>Method:</i> This was a prospective, longitudinal study of patients followed for 18 years after entering specialised treatment for substance use disorders. A sample ...
    • Centralizing a national pancreatoduodenectomy service: striking the right balance 

      Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-07)
      <i>Background</i> - Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher‐volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus on the optimal balance has not yet been reached. This observational study presents a volume–outcome analysis of a complete national cohort in a health system with ...
    • User-centred Design with a Remote Approach: Experiences from the Chronic Pain Project 

      Smaradottir, Berglind; Bellika, Johan Gustav; Fredeng, Aina; Fagerlund, Asbjørn Johansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      User-centred design involves end-users or user groups during all the parts of the development process. The research project Chronic Pain aims to develop a shared decision making application for patients and physicians, addressing individually adapted pain treatment. The project employs a user-centred design process, and in middle of it, Covid-19 pandemic social distancing restrictions were imposed. ...
    • ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial 

      Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika; Becker, Richard C; Bertilson, Maria; Budaj, Andrzej; Cornel, Jan H; Himmelmann, Anders; James, Stefan K; Siegbahn, Agneta; Storey, Robert F; Kontny, Frederic; Aukrust, Pål; Wallentin, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-29)
      <p><i>Background and aims - </i>Activated leukocyte cell adhesion molecule (ALCAM) is upregulated during inflammation and involved in transmigration of leukocytes and T-cell activation. We hypothesized that ALCAM might be associated with recurrent events in patients with acute coronary syndromes (ACS). <p><i>Methods - </i>ALCAM was measured in serum obtained on admission, at discharge, 1 month and ...
    • Comparative effectiveness of microdecompression alone vs decompression plus instrumented fusion in lumbar degenerative spondylolisthesis 

      Austevoll, Ivar Magne; Gjestad, Rolf; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Hermansen, Erland; Rekeland, Frode; Indrekvam, Kari; Hellum, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)
      <i>Importance</i> - Conflicting evidence and large practice variation are present in the surgical treatment of degenerative spondylolisthesis. More than 90% of surgical procedures in the United States include instrumented fusion compared with 50% or less in other countries.<p> <p><i>Objective</i> - To evaluate whether the effectiveness of microdecompression alone is noninferior to decompression ...
    • The prevalence of hereditary neuromuscular disorders in Northern Norway 

      Müller, Kai Ivar; Van Ghelue, Marijke; Lund, Irene; Jonsrud, Christoffer; Arntzen, Kjell Arne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-13)
      <i>Aim</i> - To investigate the point prevalence of hereditary neuromuscular disorders on January 1, 2020 in Northern Norway.<p> <p><i>Methods</i> - From January 1, 1999, until January 1, 2020, we screened medical and genetic hospital records in Northern Norway for hereditary neuromuscular disorders.<p> <p><i>Results</i> - We identified 542 patients with a hereditary neuromuscular disorder ...
    • The total prevalence of diagnosed diabetes and the quality of diabetes care for the adult population in Salten, Norway 

      Slåtsve, Kristina Barbara; Claudi, Tor; Lappegård, Knut Tore; Jenum, Anne Karen; Larsen, Marthe; Cooper, John; Sandberg, Sverre; Berg, Tore Julsrud (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-27)
      <p><i>Objective:</i> To assess the total prevalence of types 1 and 2 diabetes and to describe and compare cardiovascular risk factors, vascular complications and the quality of diabetes care in adults with types 1 and 2 diabetes in Salten, Norway. <p><i>Research design and methods:</i> Cross-sectional study including all patients with diagnosed diabetes in primary and specialist care in Salten, ...
    • Plasma levels of growth differentiation factor 15 are associated with future risk of venous thromboembolism 

      Hansen, Ellen-Sofie; Hindberg, Kristian; Latysheva, Nadezhda; Aukrust, Pål; Ueland, Thor; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-15)
      Growth differentiation factor 15 (GDF-15), a marker of inflammation and oxidative stress, has emerged as a biomarker for arterial cardiovascular disease. However, the association between GDF-15 and venous thromboembolism (VTE) remains uncertain. We therefore investigated the association between plasma GDF-15 levels and future risk of incident VTE and explored the potential of a causal association ...
    • Criteria for success after surgery for cervical radiculopathy—estimates for a substantial amount of improvement in core outcome measures 

      Mjåset, Christer; Zwart, John-Anker; Goedmakers, Caroline M.W.; Smith, Timothy R.; Solberg, Tore; Grotle, Margreth (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)
      <i>Background context</i> - Defining clinically meaningful success criteria from patient-reported outcome measures (PROMs) is crucial for clinical audits, research and decision-making.<p> <p><i>Purpose</i> - We aimed to define criteria for a successful outcome 3 and 12 months after surgery for cervical degenerative radiculopathy on recommended PROMs.<p> <p><i>Study design</i> - Prospective ...
    • Cannabis Use during Pregnancy and Risk of Adverse Birth Outcomes: A Longitudinal Cohort Study 

      Gabrhelik, Roman; Mahic, Milada; Lund, Ingunn Olea; Bramness, Jørgen Gustav; Selmer, Randi Marie; Skovlund, Eva; Handal, Marte; Skurtveit, Svetlana (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)
      <i>Background</i>: With recent changes in legislation regulating recreational and medical cannabis use around the globe, increased use in pregnancy is to be expected.<p> <p><i>Objectives</i>: To investigate the association between cannabis use during pregnancy and birth outcomes. <p> <p><i>Method</i>: Data from the Norwegian Mother and Child Cohort Study (MoBa), a prospective pregnancy cohort, ...
    • The impact of gender, puberty, and pregnancy in patients with POLG disease 

      Hikmat, Omar; Naess, Karin; Engvall, Martin; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Samsonsen, Christian; Brodtkorb, Eylert; Ostergaard, Elsebet; de Coo, Rene; Pias-Peleteiro, Leticia; Isohanni, Pirjo; Uusimaa, Johanna; Darin, Niklas; Rahman, Shamima; Bindoff, Laurence (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-18)
      <i>Objective</i> - To study the impact of gender, puberty, and pregnancy on the expression of POLG disease, one of the most common mitochondrial diseases known.<p> <p><i>Methods</i> - Clinical, laboratory, and genetic data were collected retrospectively from 155 patients with genetically confirmed POLG disease recruited from seven European countries. We used the available data to study the impact ...
    • Mental health and health related quality of life in mitochondrial POLG disease 

      Hikmat, Omar; Vederhus, Bente Johanne; Benestad, Merete Roineland; Engeset, Ida Malen E.; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Brodtkorb, Eylert; Elgen, Irene Bircow; Bindoff, Laurence (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      We aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R)and Short-Form 36 HealthSurvey (RAND-36). Wefound increased scores in all nine subscales of SCL-90-R, particularly phobic anxiety, depression and somatization. Further, patients reported considerably lower scores in all RAND-36 domains. This study revealed a ...
    • Novel bio-compatible tracers for Positron Emission Particle Tracking 

      Chang, Yu-Fen; Balakin, Boris (Conference object; Konferansebidrag, 2020-09)
      To study the flow of objects (tracers) in opaque flow processes, the PEPT (positron emission particle tracking) technique is utilized. The PEPT technique is based on the same principle of PET (positron emission tomography) which detects the characteristic back-to-back gamma pairs caused by positron-electron annihilation. The annihilation takes place within a few millimeters around the tracers labeled ...
    • Efficacy and Safety of CT-P13 in Inflammatory Bowel Disease after Switching from Originator Infliximab: Exploratory Analyses from the NOR-SWITCH Main and Extension Trials 

      Jørgensen, Kristin Kaasen; Goll, Guro Løvik; Sexton, Joe; Bolstad, Nils; Olsen, Inge C.; Asak, Øivind Wessel; Berset, Ingrid Prytz; Blomgren, Ingrid; Dvergsnes, Katrine; Florholmen, Jon; Frigstad, Svein Oskar; Henriksen, Magne; Hagfors, Jon; Huppertz-Hauss, Gert; Haavardsholm, Espen Andre; Klaasen, Rolf Anton; Moum, Bjørn; Noraberg, Geir; Prestegård, Ulf; Rydning, Jan Henrik; Sagatun, Liv; Seeberg, Kathrine; Torp, Roald; Vold, Cecilia; Warren, David J.; Ystrøm, Carl Magnus; Lundin, Knut Erik Aslaksen; Kvien, Tore Kristian; Jahnsen, Jørgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      <i>Background</i> - The NOR-SWITCH main and extension trials demonstrated that switching from originator to biosimilar infliximab (CT-P13) is efficacious and safe across six diseases. However, a subgroup analysis of Crohn’s disease (CD) in the main trial displayed a close to significant difference favouring originator infliximab, and more scientific data have therefore been requested.<p><p> <i> ...
    • Behandling av håndleddsbrudd (distale radiusfrakturer) hos voksne 

      Frønsdal, Katrine Bjørnebek; Kvernmo, Hebe Desiree; Hove, Leiv M; Husby, Torstein; Røkkum, Magne; Odinsson, Adalstein; Skoglund, Knut; Melhuus, Knut; Williksen, John Håkon; Krukhaug, Yngvar; Finsen, Vilhjalmur; Norderhaug, Inger Natvig; Juvet, Lene Kristine; Lauvrak, Vigdis; Fure, Brynjar (Research report; Forskningsrapport, 2013-02)
      I Norge er håndleddsbrudd (distale radiusfrakturer) den vanligste bruddtypen, med en forekomst på ca. 15000 per år. Ved brudd med ingen eller lite feilstilling er det vanlig å behandle med gips. Ved brudd med feilstilling er det aktuelt med mer avanserte teknikker. Det er imidlertid uklart hvilke pasienter som bør opereres og hvem som bør få annen behandling, samt hvilke operasjons-metoder som har ...
    • Svake høyfrekvente elektromagnetiske felt - en vurdering av helserisiko og forvaltningspraksis 

      Alexander, Jan; Brunborg, Gunnar; Feychting, Maria; Forsberg, Ellen-Marie; Gismervik, Svein; Haanes, Jan Vilis; Hamnerius, Yngve; Hannevik, Merete; Heimdal, Per Eirik; Hillert, Lena; Klæboe, Lars Hind Bakken; Kristensen, Petter; Moen, Bente Elisabeth; Oftedal, Gunnhild; Tynes, Tore; Langeland, Bjørn Tore (Research report; Forskningsrapport, 2012-08)
      Bruk av utstyr som sender ut radiobølger har økt i senere år. Trådløs kommunikasjonsteknologi som mobiltelefoni dominerer. De siste årene har krav om stadig bedre dekning, teknologi i nye generasjoner og utvidede funksjoner på de mobile tjenestene ført til en betydelig økning av antallet og tettheten av radiosendere. Eksponering for elektromagnetiske felt (EMF) og mulige helseeffekter er sterkt ...
    • Description of health-related rehabilitation service provision and delivery in randomized controlled trials: A topic review 

      Andelic, Nada; Lu, Juan; Gutenbrunner, Christoph; Nugraha, Boya; Gormley, Mirinda; Søberg, Helene; Sveen, Unni; Anke, Audny; Kirkevold, Marit; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-18)
      Objective: To determine how health-related rehabilitation services have been described in recently pub-lished randomized clinical trials, using the International Classification System for Service Organization in Health-Related Rehabilitation (ICSO-R 2.0) as a framework.<p><p> Methods: Medline was searched for English--language randomized clinical trials (RCTs) published between 1 January 2018 and ...