A renaissance of microRNAs as taxonomic and phylogenetic markers in animals
Permanent link
https://hdl.handle.net/10037/35201Date
2024-06-21Type
Journal articleTidsskriftartikkel
Peer reviewed
Author
Fromm, BastianAbstract
Molecular markers for tracing animal sample origins and compositions are critical for applications such as parasite detection, contamination screening, and
sample authentication. Among these, microRNAs have emerged as promising
candidates due to their deep conservation, near-hierarchical evolution, and sta bility. I here review the suitability of microRNAs as taxonomic and also phylo genetic markers and show how careful annotation efforts and the establishment
of the curated microRNA gene database MirGeneDB and tools like MirMachine
have revitalized microRNA research. These advancements enable accurate phy logenetic and taxonomic studies, highlighting microRNAs' potential in resolving
long-standing questions in animal relationships and extending to applications in
ancient DNA and environmental RNA analysis. Future research must focus on
expanding microRNA complements across all Metazoa and further improving
annotation methodologies.
Publisher
WileyCitation
Fromm. A renaissance of microRNAs as taxonomic and phylogenetic markers in animals. Zoologica Scripta. 2024Metadata
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