Background - Complex high-precision radiotherapy, such as stereotactic body radiotherapy (SBRT), should only be offered to patients with sufficiently long survival. In the context of bone metastases radiotherapy, low rates of treatment close to the end of life, e.g. last 30 days (RT30), may serve as a quality of care indicator. While traditional, pain-relieving short-course regimens have been studied ...

Background The therapeutic use of intermittent theta burst stimulation (iTBS) delivered to the left dorsolateral prefrontal cortex (LDLPFC) is a relatively new but promising treatment option for depression. There is a need for more knowledge on the mechanisms involved in its antidepressant effects.<p> <p>Methods This is a single-centre, prospective, randomized, double-blind, placebo-controlled ...

Norway’s integration programme for newly arrived refugees is mandatory, and is offered by all municipalities. The programme offers courses in social studies, Norwegian language and parental guidance. In 2023, it was decided to allow municipalities to adapt and shorten the latter course for families from Ukraine due to capacity constraints. To make informed adaptations, the municipalities need more ...

<p><i>Introduction</i> The spectrum of COVID-19 manifestations makes it challenging to estimate the exact proportion of people who had the infection in a population, with the proportion of asymptomatic cases likely being underestimated. We aimed to assess and describe the spectrum of COVID-19 cases in a sample of adult population aged 40–74 years in Arkhangelsk, Northwest Russia, a year after the ...

Antimicrobial resistance has long been a problem and a struggle to compromise as life-threatening infections are harder to treat. Among common pathogens, Klebsiella pneumoniae (K.pneumoniae) can be a highly resistant bacteria associated with increased mortality when infecting critically ill and immunocompromised patients. Prevalence of gastrointestinal carriage depends on several risk factors. ...

Det var en stor ære for meg å motta forskningsprisen. Jeg er takknemlig, ydmyk og stolt overfor Norsk cardiologisk selskap (NCS) og juryen. Få fra miljøet i Tromsø har mottatt prisen, og innenfor fagområdet preventiv kardiologi er det heller ikke mange prismottakere. Jeg ble veldig glad. Det var en stor begivenhet for meg å bli hyllet av mine kolleger, både fra min egen hjertemedisinske avdeling og ...

Objective: The aim of this study was to explore Sámi healthcare staff experiences in encounters with Sámi patients and their expectations for non-Sámi healthcare staff. Methods: Focus groups and individual interviews with 14 participants were conducted, and the participants’ experiences were subjected to a thematic analysis approach. <p> <p>Results: The findings show that the Sámi healthcare staff ...

Introduction: Maternal-neonatal healthcare services were severely disrupted during the COVID-19 pandemic in even high-income countries within the World Health Organization (WHO) European Region. The objective of this study was to compare trends in the quality of maternal and neonatal care (QMNC) in Sweden and Norway to 12 other countries from the WHO European Region during the COVID-19 pandemic, and ...

BACKGROUND: Resistance to chemotherapy, combined with heterogeneity among resistant tumors, represents a significant challenge in the clinical management of triple negative breast cancer (TNBC). By dissecting molecular pathways associated with treatment resistance, we sought to define patient sub-groups and actionable targets for next-line treatment.<p> <p>METHODS: Bulk RNA sequencing and reverse ...

Emergency departments (EDs) handle urgent medical needs for a diverse population. Medication errors and adverse drug events pose safety risks in the ED. Clinical pharmacists, experts in medication use, play a crucial role in identifying and optimizing medication therapy. The aim of this study was to investigate how clinical pharmacists introduced into the ED interdisciplinary teams distribute ...