Det helsevitenskapelige fakultet: Recent submissions

Now showing items 1601-1620 of 10439

    • «Det er trøst i regnbuens farger» – omgivelsenes trøstende funksjon i sykepleien 

      Kitzmüller, Gabriele (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-14)
      I dette essayet vil jeg belyse fenomenet trøst i sykepleien. Jeg tar utgangspunkt i min erfaring som pårørende til en kjær venninne som tilbragte sine siste dager på sykehus. Personalet på avdelingen ga oss anledning til å sette et hjemlig preg på hennes sykerom. Atmosfæren i dette rommet gjorde at vi som var der, følte trygghet, ro og velvære til tross for alvoret i situasjonen. Dette gjorde oss ...

    • Shortened Palliative Radiotherapy Results in a Lower Rate of Treatment During the Last Month of Life 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-25)
      Introduction Palliative radiotherapy (PRT) during the last month of life (PRT30) should be avoided because relevant clinical benefits are unlikely to occur. While traditional short-course fractionation regimens are suitable for most patients, a minority may derive gains from higher doses of PRT. Compared to older regimens such as 13 fractions of 3 Gy, more hypofractionated, non-ablative concepts ...

    • Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing 

      Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M. A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J. K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, W. M. Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher; Levy, Renata Bertazzi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, ...

    • Deep learning-derived cardiovascular age shares a genetic basis with other cardiac phenotypes 

      Libiseller-Egger, Julian; Phelan, Jody E.; Attia, Zachi I.; Benavente, Ernest Diez; Campino, Susana; Friedman, Paul A.; Lopez-Jimenez, Francisco; Leon, David A.; Clark, Taane G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-31)
      Artifcial intelligence (AI)-based approaches can now use electrocardiograms (ECGs) to provide expertlevel performance in detecting heart abnormalities and diagnosing disease. Additionally, patient age predicted from ECGs by AI models has shown great potential as a biomarker for cardiovascular age, where recent work has found its deviation from chronological age (“delta age”) to be associated ...

    • A global experiment on motivating social distancing during the COVID-19 pandemic 

      Legate, Nicole; Nguyen, Thuy-vy; Weinstein, Netta; Lund, Maria Louise; Klevjer, Kristoffer; Kunst, Jonas R.; Pfuhl, Gerit; Schei, Vidar; Korbmacher, Max; Tamnes, Christian Krog; Bundt, Carsten; Askelund, Adrian Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-27)
      Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an ...

    • Borte bra, men hjemme best 

      Skjelbakken, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-24)
      Jeg var tre år og alene første gang jeg var i Oslo og på Rikshospitalet. Sykehuset syntes den gang at «barna var mye enklere å ha med å gjøre uten foreldrene». Kontrasten var stor da jeg 54 år senere kom tilbake til sykehuset, som nærmeste pårørende til en voksen sønn som skulle gjennomgå allogen stamcelletransplantasjon.

    • The effect of resolvin D1 on bone regeneration in a rat calvarial defect model 

      Jiang, Xiaofeng; Liu, Jing; Li, Si; Qiu, Yingfei; Wang, Xiaoli; He, Xiaoli; Pedersen, Torbjørn Østvik; Mustafa, Kamal Babikeir Elnour; Xue, Ying; Mustafa, Manal; Kantarci, Alpdogan; Xing, Zhe (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-18)
      Resolvin D1 (RvD1) is a pro-resolving lipid mediator of inflammation, endogenously synthesized from omega-3 docosahexaenoic acid. The purpose of this study was to investigate the effect of RvD1 on bone regeneration using a rat calvarial defect model. Collagen 3D nanopore scaffold (COL) and Pluronic F127 hydrogel (F127) incorporated with RvD1 (RvD1-COL-F127 group) or COL and F127 (COL-F127 group) ...

    • Association between copy number variations in the OCA2-HERC2 locus and human eye colour 

      Salvo, Nina Mjølsnes; Janssen, Kirstin; Olsen, Gunn-Hege; Berg, Thomas; Andersen, Jeppe Dyrberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-29)
      Human eye colour variation is strongly associated with single nucleotide polymorphisms (SNPs) in the OCA2- HERC2 locus, especially rs12913832 that is found in an enhancer element of OCA2. In a previous study we found that 43 out of 166 individuals in a Norwegian population with the brown eye colour genotype HERC2 rs12913832:AA or AG, did not have the expected brown eye colour. To investigate if ...

    • Har pasienter rett til behanding med legemidler som Beslutningsforum har avslått? 

      Lindekleiv, Haakon; Giverhaug, Trude; Henriksen, Marte Lødemel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-21)
      Statsforvalteren i Agder har nylig gitt en pasient rett til behandling med et legemiddel som Beslutningsforum har avslått. Hvilke konsekvenser får dette?

    • Gule stafylokokker hos barn 

      Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      Antibiotikastyring er et av de viktigste tiltakene mot resistensutvikling. Ved hud- og bløtdelsinfeksjoner hos barn skal vi fortsatt ha en nøktern forskrivningspraksis.

    • Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases 

      Seim, Bjørn Edvard; Holt, Margrethe Flesvig; Ratajska, Aleksandra; Michelsen, Annika Elisabet; Ringseth, Monica Myklebust; Halvorsen, Bente; Skjelland, Mona; Kvitting, John-Peder; Lundblad, Runar; Krohg-Sørensen, Kirsten; Osnes, Liv T. N.; Aukrust, Pål; Paus, Benedicte; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-20)
      Background: In approximately 20% of patients with thoracic aortic aneurysms or dissections a heritable thoracic aortic disease (HTAD) is suspected. Several monogenic connective tissue diseases imply high risk of aortic disease, including both non-syndromic and syndromic forms. There are some studies assessing inflammation and extracellular matrix remodeling in patients with non-hereditary aortic ...

    • Surgery for degenerative cervical myelopathy in patients with rheumatoid arthritis and ankylosing spondylitis: a nationwide registry-based study with patient-reported outcomes 

      Holmberg, Siril Therese; Gulati, Agnete Malm; Johansen, Tonje Okkenhaug; Salvesen, Øyvind; Vangen-Lønne, Vetle; Solberg, Tore; Tronvik, Erling Andreas; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-15)
      Purpose To compare patient-reported outcomes (PROMs) following surgery for degenerative cervical myelopathy (DCM) among patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS) versus those without rheumatic diseases. Methods Data were obtained from the Norwegian Registry for Spine Surgery. The primary outcome was change in the Neck Disability Index (NDI) at 1 year. Secondary endpoints ...

    • The Sexual Incentive Motivation Model and Its Clinical Applications 

      Ågmo, Anders j; Laan, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-15)
      Sexual motivation (desire) requires the simultaneous presence of an active central motive state and a stimulus with sexual significance. Once activated, sexual motivation leads to visceral responses and approach behaviors directed toward the emitter of the sexual stimulus. In humans, such behaviors follow cognitive evaluation of the context, including predictions of the approached individual’s ...

    • A Systematic Review and Meta-Analysis of Measurement Feedback Systems in Treatment for Common Mental Health Disorders 

      Rognstad, Kristian; Wentzel-Larsen, Tore; Neumer, Simon-Peter; Kjøbli, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)
      To investigate the efects of measurement feedback systems (MFSs) in therapy on mental health outcomes through a literature review and meta-analysis. Using a three-level modeling approach, we conducted a meta-analysis of all efect sizes from randomized controlled studies of MFSs used in the treatment of common mental health disorders. Eighty-two efect sizes were extracted from the thirty-one included ...

    • Age, income and sleep duration were associated with outcomes in children participating in weight management 

      Kjetså, Ingrid; Halvorsen, Peder Andreas; Kokkvoll, Ane Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-23)
      Aim To explore associations between baseline factors and weight-related outcomes among participants enrolled in a paediatric obesity trial. Methods We included children aged 6–12 years participating in a 2-year multidisciplinary family programme who attended a postintervention follow-up 36 months from baseline (n = 62). Outcome measures were change in body mass index standard deviation score (BMI ...

    • Mercury, silver and selenium in serum before and after removal of amalgam restorations: results from a prospective cohort study in Norway 

      Björkman, Lars; Musial, Frauke; Alræk, Terje; Werner, Erik Lønnmark; Hamre, Harald J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)
      <p><b> Objective</b> A prospective cohort study on changes of health complaints after removal of amalgam restorations was carried out at the request of the Norwegian Directorate of Health. The aim was to provide and evaluate experimental treatment to patients with health complaints attributed to dental amalgam fillings. <p><b> Methods</b> Patients (n = 32) with medically unexplained ...

    • Reproductive changes among women in their 40s: A cross-sectional study 

      Lindh, Ingela; Skjeldestad, Finn Egil; Heikinheimo, Oskari; Hognert, Helena; Lidegaard, Øjvind; Bergh, Christina; Gemzell-Danielsson, Kristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-05)
      Introduction The aim was to describe and compare changes in the reproductive pattern of women in their 40s observed over a decade in Scandinavia. Material and Methods Cross-sectional study using the total population of women aged 40–49 years between 2008–2018 in Denmark, Norway and Sweden (on average n = 1.5 million). Aggregated data concerning birth and induced abortion rate were collected and ...

    • The impact of implementing patient-reported measures in routine maternity care: a systematic review 

      Chen, An; Väyrynen, Kirsi; Schmidt, Alexandra; Leskelä, Riikka-Leena; Torkki, Paulus; Heinonen, Seppo; Tekay, Aydin; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-05)
      Introduction While there is growing interest in applying patient-reported measures (PRMs) in clinical routine, limited collective evidence of the impact of PRMs hinder their widespread use in specific contexts, such as maternity care. Our objective was to synthesize existing emperical evidence on the impact of implementing PRMs in routine maternity care. Material and methods We followed the ...

    • Validity and responsiveness of GHC-index in patients with amalgam-attributed health complaints 

      Lamu, Admassu Nadew; Robberstad, Bjarne; Hamre, Harald J.; Alræk, Terje; Musial, Frauke; Björkman, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-15)
      <p><b> Objective</b> Many patients have medically unexplained physical symptoms (MUPS); some of them attribute their health complaints to dental amalgam fillings. The aim of this study was to assess the validity and responsiveness of General Health Complaints index (GHC-index) for measuring the symptom load in MUPS patients compared to the widely used symptom outcome measure, Giessen Subjective ...

    • Leger utdannet i Bodø – hvem er de og hvor blir de av? 

      Westlie, Åsa Langen; Gaski, Margrete; Abelsen, Birgit; Grimstad, Hilde; Ofstad, Eirik Hugaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)
      <p><b> BAKGRUNN</b> Siden 2009 har inntil 24 legestudenter ved Universitetet i Tromsø årlig fullført de to siste årene av utdanningen i Bodø (kalt Bodøpakken). Vi kartla oppvekstkommune, ønsker for framtidig spesialitet blant studentene og hvor og hva studentene arbeidet med etter LIS1-tjenesten. <p><b> MATERIALE OG METODE</b> Legestudenter uteksaminert i Bodø i perioden 2012–18 fikk et ...