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norskDet helsevitenskapelige fakultet: Recent submissions
Now showing items 1621-1640 of 10439
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External Validation of the Graded Prognostic Assessment in Patients with Brain Metastases from Small Cell Lung Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-29)Background: Recently, graded prognostic assessment (GPA) for small cell lung cancer (SCLC) patients with brain metastases has been developed. This includes age, performance status, number of brain metastases and presence of extracranial metastases. The aim of the present study was to validate this four-tiered prognostic score in a European cohort of patients. Methods: The retrospective validation ... -
Eating and speech problems in oral and pharyngeal cancer survivors – Associations with treatment-related side-effects and time since diagnosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-18)Aims: The aim of this cross-sectional study was to find factors associated with problems with the ability to eat and speak in oral and pharyngeal cancer (OPC) survivors and to evaluate if the panorama of oral problems varied with time since diagnosis.<p> <p>Methods and Results: A questionnaire assessing cancer diagnosis and treatment, oral health-related quality of life, and presence of ... -
Epidemiology and natural history in 101 subjects with FKRP-related limb-girdle muscular dystrophy R9. The Norwegian LGMDR9 cohort study (2020)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)We aimed to investigate the epidemiology and natural history of FKRP-related limb-girdle muscular dystrophy R9 (LGMDR9) in Norway. We identified 153 genetically confirmed subjects making the overall prevalence 2.84/100,000, the highest reported figure worldwide. Of the 153 subjects, 134 (88 %) were homozygous for FKRP c.826C>A giving a carrier frequency for this variant of 1/101 in Norway. Clinical ... -
The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3-fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self-reported information from 35 525 women from the ... -
Trøstens stille stemme i helsesykepleiekonsultasjoner
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)Å gi trøst er en integrert del av sykepleie, og å få trøst er et grunnleggende menneskelig behov. I dette vitenskapelige essayet ser vi nærmere på hvordan fenomenet trøst kommer til uttrykk i norsk helsesykepleiepraksis. Helsesykepleiere i Norge yter ikke pleietjenester, men tilbyr helsefremmende og forebyggende helsetjenester til barn og unge mellom 0 og 20 år. Deres omsorgspraksis har blitt beskrevet ... -
Experimental long-distance haplotyping of OCA2-HERC2 variants
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-18)The regulatory HERC2 SNP, rs12913832, is strongly associated with blue and brown eye colour. However, eye colour in heterozygous rs12913832 individuals is observed to vary greatly. Missense mutations in OCA2, such as rs1800407 and rs74653330, are associated with lighter eye colour in some but not all heterozygous rs12913832 individuals. Determining the physical linkage of these variants might ... -
Quality of health care around the time of childbirth during the COVID-19 pandemic: Results from the IMAgiNE EURO study in Norway and trends over time
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-18)Objective: To describe maternal perception of the quality of maternal and newborn care (QMNC) in facilities in Norway during the first year of COVID-19 pandemic.<p> <p>Methods: Women who gave birth in a Norwegian facility from March 1, 2020, to October 28, 2021, filled out a structured online questionnaire based on 40 WHO standards-based quality measures. Quantile regression analysis was performed ... -
Modelling fatty liver disease with mouse liver-derived multicellular spheroids
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)Chronic liver disease can lead to liver fibrosis and ultimately cirrhosis, which is a significant health burden and a major cause of death worldwide. Reliable in vitro models are lacking and thus mono-cultures of cell lines are still used to study liver disease and evaluate candidate anti-fibrotic drugs. We established functional multicellular liver spheroid (MCLS) cultures using primary mouse ... -
First-time parents' experiences related to parental self-efficacy: A scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-23)Becoming a parent for the first time is a major transition, and parental self‐efficacy (PSE) is considered an important predictor of parenting functioning. We aimed to describe and synthesize qualitative studies that explore first‐time parents' experiences related to PSE in the transition to parenthood in the first‐year postpartum. We conducted a scoping review in accordance with international ... -
Magnetic resonance imaging for non-invasive measurement of plastic ingestion in marine wildlife
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)Monitoring plastic ingestion by marine wildlife is important for both characterizing the extent of plastic pollution in the environment and understanding its effect on species and ecosystems. Current methods to detect plastic in the digestive system of animals are slow and invasive, such that the number of animals that can be screened is limited. In this article, magnetic resonance imaging (MRI) ... -
Hvordan trøster du spedbarnet ditt? Et spenningsfelt mellom intuitiv adferd, kultur og kunnskap
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)Dette essayet omhandler spedbarnstrøst. Hvorfor trøst er så betydningsfullt for spedbarnet, og hvordan omsorgspersoners kapasitet til å trøste påvirkes av intuitiv adferd, kultur og nyere forskning og erfaringsbasert kunnskap. Trøst i denne livsfasen er innspunnet i grunnleggende omsorg, og barnet behøver hyppig støtte til å dempe uhensiktsmessig aktivitet i et umodent nervesystem. Det essensielle ... -
Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung ... -
Strong pathogen competition in neonatal gut colonisation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-01)Opportunistic bacterial pathogen species and their strains that colonise the human gut are generally understood to compete against both each other and the commensal species colonising this ecosystem. Currently we are lacking a population-wide quantification of strain-level colonisation dynamics and the relationship of colonisation potential to prevalence in disease, and how ecological factors ... -
Symptoms of Depression, Anxiety, and Posttraumatic Stress among Patients with Cardiac Pacemakers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-15)Despite being a prerequisite for tailoring specific therapeutic interventions, knowledge of pattern and prevalence of clinically significant psychiatric symptomatology among patients with cardiac pacemakers (PMs), especially of symptoms of posttraumatic stress, is limited. We studied symptoms of depression, anxiety, and posttraumatic stress among PM patients (PM due to syncope or presyncope) ... -
Impact supplement of the strengths and difficulties questionnaire in the assessment of functional impairment in children with ADHD or ASD in a mixed neuropediatric sample: A partial validation study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-30)Background: In addition to symptoms of neurodevelopmental disorders, functional impairment is crucial to the determination of clinical significance. The aim of this study was to examine partial validity and usefulness of the Strengths and Difficulties Questionnaire’s (SDQ) impact supplement (SDQ impact) in measuring functional impairment in children and adolescents diagnosed with attention ... -
Stable and unstable associations between learning environment factors and study approaches: two consecutive cross-sectional analyses of Norwegian occupational therapy students
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-24)Relationships between learning environment variables and students’ approaches to studying have been investigated from many points of view over the last decades. However, few studies have explored whether such relationships are stable over time. In the two consecutive cross-sectional analyses performed in this study, Norwegian occupational therapy students’ perceptions of their learning environment ... -
Autonomous or controlled self-regulation, that is the question: A self-determination perspective on the impact of commuting on employees’ domain-specific functioning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-01)The few studies that have considered psychological processes during the commute have drawn an ambiguous picture, with some emphasizing the negative and others the positive consequences of commuting. Drawing on self-determination theory, we develop a framework that expands on the costs and benefits of commuting for employees’ subsequent domain-related functioning at work and home. Specifically, we ... -
Trøst som oppmerksomt nærvær i mellommenneskelig profesjonell praksis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-30)I dette vitenskapelige essayet synliggjøres trøstens betydning i mellommenneskelige profesjonelle praksiser. Forfatterne viser gjennom to adskilte forskningsprosjekter i to ulike fagfelt, betydningen av å ha et sansene oppmerksomt nærvær i møte med mennesker som erfarer at livet er krevende eller truet grunnet sykdom eller andre eksistensielle grunnvilkår. I essayet er det trøstens fremtredelser ... -
Management of Orofacial Manifestations of Juvenile Idiopathic Arthritis: Interdisciplinary Consensus-Based Recommendations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)Involvement of the temporomandibular joint (TMJ) is common in juvenile idiopathic arthritis (JIA). TMJ arthritis can lead to orofacial symptoms, orofacial dysfunction, and dentofacial deformity with negative impact on quality of life. Management involves interdisciplinary collaboration. No current recommendations exist to guide clinical management. We undertook this study to develop consensus-based ... -
The meaning of biology in the foster family narratives of young adults
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-14)While biological relatedness has been an issue among anthropologists for some time, the topic has gained little interest in family sociology. Recent contributions exploring how genetic thinking – the process through which biological relationships are rendered meaningful in everyday family living – shapes family life, suggest that this is about to change. This article seeks to contribute to this ...
