Background: Precision cancer medicine (PCM), frequently used for the expensive and often modestly efficacious off-label treatment with medications matched to the tumour genome of end-stage cancer, challenges healthcare resources. We compared the health effects, costs and cost-effectiveness of our MetAction PCM study with corresponding data from comparator populations given best supportive care ...

Background. Immune dysregulation is a major factor in the development of severe coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 have been implicated as mediators of tissue inflammation, but data on their regulation in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is limited. We thus investigated the levels of these chemokines in COVID-19 ...

<p><b>Objective</b> This study aimed to report the presence of categorical and dimensional personality disorders (PD) in adults with longstanding eating disorders (ED) over a period of 17 years and to investigate whether changes in PD predict changes in ED symptoms or vice versa. <p><b>Methods</b> In total, 62 of the 80 living patients (78% response rate) with anorexia nervosa (<i>n</i> ...

This chapter focuses on the topic of character portrayals with autism spectrum disorders (ASD) in film and TV-series. We address this topic by presenting research from the general psychiatric field before we discuss the research on portrayals of characters with ASD. We will also provide the reader with some examples of films and TV-series that have been given particular attention in the popular media ...

Currently, approximately 2% of the general population will experience at least one chronic wound throughout their lifetime. The numbers are expected to rise due to an aging population with a heightened disease burden. These wounds are major burdens for the patients; therefore, we need to find innovative approaches for bacterial eradication and improved wound treatment. We aimed to utilize nature’s ...

Background: Health anxiety (HA) is defined as a worry of disease. An association between HA and mental illness has been reported, but few have looked at the association between HA and physical disease. Objective: To examine the association between HA and number of diseases, different disease categories and cardiovascular risk factors in a large sample of the general population.<p> <p>Methods: ...

This qualitative research explores interprofessional learning among health students within a mental health outpatient setting. The focus is on how they manage to establish a boundary-crossing community of practice. Six final year students from medicine, occupational, and physical therapy, divided into two groups, visited elderly clients living at home on two occasions. Based on an assessment of the ...

Gjennom fokus på samvalg, mål og åpen dialog om hjelpebehov er vurderingssamtalen en gyllen mulighet for å skape tillit, engasjement og håp – og sikre at de kommer inn riktig dør til psykisk helsevern for barn og unge (PHBU).

<p><i>Staphylococcus aureus</i> is a Gram-positive opportunistic pathogen responsible for a range of infections that can lead to fatal invasive diseases such as pneumonia or osteomyelitis. Approximately 30% of the healthy adult population are persistently colonized by <i>S. aureus</i> strains in their anterior nares. The molecular mechanism underlying <i>S. aureus</i> colonization and infection ...

Venøs tromboembolisme (VTE), bestående av dyp venetrombose (DVT) og lungeemboli (PE), er en utbredt og multifaktoriell sykdom med langtidskomplikasjoner som negativt påvirker fysisk funksjon og livskvalitet. Sosioøkonomisk status (SES) er kjent for å påvirke både risiko og prognose for helsemessige og helserelaterte utfall. Selv om assosiasjoner mellom VTE og fysisk helse er godt dokumentert, finnes ...