Background: Patients with extreme body mass indices (BMI) could have an increased risk of death while hospitalized for COVID-19.<p> <p>Methods: The database of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) was used to assess the time to in-hospital death with competing-risks regression by sex and between the categories of BMI. <p>Results: Data from 12,137 ...

Purpose: Fracture risk is most frequently assessed using Dual X-ray absorptiometry to measure areal bone mineral density (aBMD) and using the Fracture Risk Assessment Tool (FRAX). However, these approaches have limitations and additional bone measurements may enhance the predictive ability of these existing tools. Increased cortical porosity has been associated with incident fracture in some ...

<p><i>Background -</i> Soluble guanylate cyclase, sGC, is a major contributor to the signal transduction in the cardiovascular system, and dysfunction in the NO-sGC-cGMP signaling plays an important role in cardiovascular disease. This system is sensitive to a wide variety of pathological conditions spanning from substrate shortage to sGC-insensitivity to nitric oxide (NO), during pathological ...

Krigen i Ukraina aktualiserer vår beredskap ved atomhendelser. Myndighetene anbefaler at voksne under 40 år, gravide, ammende og barn under 18 år har jodtabletter tilgjengelig. Jodprofylakse kan redusere risikoen for skjoldbruskkjertelkreft, og råd om inntak kommer ofte med en samtidig anbefaling om å holde seg innomhus.

The purpose of this review is to present the current knowledge on the clinical use of several forms of cell therapy in hematological malignancies and the preclinical models available for their study. In the context of allogeneic hematopoietic stem cell transplants, mesenchymal stromal cells are pursued to help stem cell engraftment and expansion, and control graft versus host disease. We further ...

Background: People living with HIV, who take antiretroviral therapy (ART), often enjoy long and healthy lives, but this therapy has well known metabolic adverse efects. Physical activity is found to be an important factor in improving these physiological parameters. This study aimed to determine physical activity level and associated factors among HIV patients in Ethiopia.<p> <p>Methods: An institutional ...

Background: Multimorbidity is one of the greatest health-related challenges worldwide. Multimorbidity is associated with several outcomes, such as lower quality of life and higher disability. The main aim of this study was to explore the association between multimorbidity and the use of healthcare services in primary healthcare. Method: In a register-based, cross-sectional study we extracted data ...

The aim of this study was to investigate the possible beneficial effects of exercise training (ET) with omega-3/Calanus oil supplementation on cardiorespiratory and adiposity parameters in elderly women. Fifty-five women (BMI: 19–37 kg/m² , 62–80 years old) were recruited and randomly assigned to the 4 month intervention with ET and omega-3 supplementation (Calanus oil, ET-Calanus) ...

Objective: To examine the impact of posttraumatic stress on the choice of responses to and attribution of intentionality in peer provocation in adolescent boys and girls. Methods: A sample of 2678 adolescents from Northern Russia, aged 13–17 years (59.3% female; 95.7% ethnic Russian) completed self-reports on posttraumatic stress and rated hypothetical peer provocation scenarios that teenagers ...

Aim To test the association of alcohol consumption with total and cause-specific mortality risk. Design Prospective observational multi-centre population-based study. Setting Sixteen cohorts (15 from Europe) in the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) Project. Participants A total of 142 960 individuals (mean age 50 ± 13 years, 53.9% men). Measurements Average alcohol intake by ...