Det helsevitenskapelige fakultet: Recent submissions

Now showing items 1-20 of 10644

    • HIV Testing and Treatment among HIV-Positive Men who have Sex with Men (MSM) Living in Russia: Data from Two Waves of the European MSM Internet Survey 

      Berg, Rigmor; Skogen, Vegard; Schmidt, Axel J.; Nesterov, Roman; Beloglazov, Andrey (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-02)
      We examined changes in HIV testing and medical care among men who have sex with men (MSM) in Russia. Data come from the 2010 and 2017 waves of the European MSM Internet Survey. From 2010 to 2017 there was an increase in the proportion who had ever received an HIV test (+11.2%), had tested for HIV in the last year (+2.1%), had ever taken antiretroviral therapy (ART) (+31.9), were currently taking ...

    • Acquisition of peak bone mass in a Norwegian youth cohort : longitudinal findings from the Fit Futures study 2010–2022 

      Sagelv, Edvard Hamnvik; Emaus, Nina Alice; Evensen, Elin Kristin; Christoffersen, Tore; Dennison, Elaine; Furberg, Anne-Sofie; Grimnes, Guri; Johansson, Jonas Lars; Nielsen, Christopher Sivert; Nilsen, Ole Andreas; Winther, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-03)
      Summary In a Norwegian youth cohort followed from adolescence to young adulthood, bone mineral density (BMD) levels declined at the femoral neck and total hip from 16 to 27 years but continued to increase at the total body indicating a sitespecifc attainment of peak bone mass.<p> <p>Purpose To examine longitudinal trends in bone mineral density (BMD) levels in Norwegian adolescents into ...

    • A comparative genomic and phenotypic study of Vibrio cholerae model strains using hybrid sequencing 

      Lorentzen, Øyvind Myrvoll; Bleis, Christina; Abel, Sören (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-23)
      Next-generation sequencing methods have become essential for studying bacterial biology and pathogenesis, often depending on high-quality, closed genomes. In this study, we utilized a hybrid sequencing approach to assemble the genome of C6706, a widely used Vibrio cholerae model strain. We present a manually curated annotation of the genome, enhancing user accessibility by linking each coding sequence ...

    • Intermittent protein restriction elevates food intake and plasma ghrelin in male mice 

      Volcko, Karin Linnea; Taghipourbibalan, Hamid; Mccutcheon, James Edgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-10)
      Low-protein diets affect body weight, body composition, food intake, and food preferences in mice. Furthermore, single periods of protein restriction can have lasting effects on these parameters. We sought to examine the effect of multiple, short, bouts of protein restriction, relative to long-term maintenance on either a control (NR) or protein-restricted (PR) diet. We found that male mice experiencing ...

    • Validation of two LC–HRMS methods for large-scale untargeted metabolomics of serum samples: Strategy to establish method fitness-for-purpose 

      Grijseels, Sietske; Vasskog, Terje; Heinsvig, Pia J.; Myhre, Torbjørn Norberg; Hansen, Terkel; Mardal, Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-06)
      Untargeted metabolomics by LCsingle bondHRMS is a powerful tool to enhance our knowledge of pathophysiological processes. Whereas validation of a bioanalytical method is customary in most analytical chemistry fields, it is rarely performed for untargeted metabolomics. This study aimed to establish and validate an analytical platform for a long-term, clinical metabolomics study. Sample preparation ...

    • 'What i thought was the dream job was a little different than i had expected': A qualitative study exploring the turnover of IPS employment specialists 

      Butenko, Daniil; Rinaldi, Miles; Moe, Cathrine Fredriksen; Brinchmann, Beate; Wittlund, Sina Marion; Killackey, Eoin; Borg, Marit; Mykletun, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-09)
      BACKGROUND: Individual Placement and Support (IPS) is an evidence-based vocational rehabilitation program that helps people with severe mental problems to obtain and maintain paid jobs. Turnover of IPS employment specialists is a scarcely studied subject that can undermine the effectiveness and implementation of the intervention.<p> <p>OBJECTIVE: This study aimed to explore and describe the ...

    • Infeksjonsovervåkning på sykehjem gjennom 18 måneder under og etter covid-19-pandemien 

      Sandbekken, Ida Hellum; Hermansen, Åsmund; Grov, Ellen Karine; Utne, Inger; Løyland, Borghild (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-16)
      Bakgrunn: Helsetjenesteassosierte infeksjoner er en viktig årsak til lidelse og død blant beboere på sykehjem. Mange av infeksjonene behandles med antibiotika. Dette høye forbruket kan øke den antimikrobielle resistensen, som er et av de største globale folkehelseproblemene. Det viktigste tiltaket for å redusere antibiotikabruken er å redusere antallet infeksjoner. Overvåkning av infeksjoner er en ...

    • Physiotherapists' Treatment Strategies and Delineation of Areas of Responsibility for People With Musculoskeletal Conditions and Comorbidities in Private Physiotherapy Practice: A Qualitative Study 

      Lyhnebeck, Anna Bernhardt; Risør, Mette Bech; Guassora, Ann Dorrit; Andersen, John Sahl; Skou, Søren Thorgaard (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-29)
      Background - Patients with multiple chronic conditions, for example, musculoskeletal conditions and comorbidities, often receive inadequate and sometimes even contradictory care. Physiotherapists are well qualified to manage patients with musculoskeletal conditions and comorbidities due to their education and experience with rehabilitation; however, it is unknown which challenges they face when ...

    • Patients with axial spondyloarthritis reported willingness to use remote care and showed high adherence to electronic patient-reported outcome measures: an 18-month observational study 

      Thomassen, Emil E. Kvernberg; Berg, Inger Jorid; Kristianslund, Eirik; Tveter, Anne Therese; Bakland, Gunnstein; Gossec, Laure; Hakim, Sarah; Macfarlane, Gary John; de Thurah, Annette; Østerås, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-21)
      Remote monitoring using electronic patient reported outcomes (ePROs) in axial spondyloarthritis (axSpA) may improve self-management and reduce the need for consultations. However, knowledge regarding patients’ willingness to use remote care and adherence to reporting ePROs is scarce. The objective of this study was to assess axSpA patients’ willingness to use remote care and adherence to reporting ...

    • ESR Essentials: imaging of suspected child abuse—practice recommendations by the European Society of Paediatric Radiology 

      Colleran, Gabrielle C.; Fossmark, Maria Olsen; Rosendahl, Karen; Argyropoulou, Maria; Mankad, Kshitij; Offiah, Amaka C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-18)
      The goal of this paper is to provide a useful desktop reference for the imaging of suspected child abuse with clear, age-specific pathways for appropriate evidence-based imaging and follow-up.<p> <p>We aim to provide a road map for the imaging evaluation and follow-up of this important and vulnerable cohort of patients presenting with signs and symptoms concerning for inflicted injury. As the ...

    • Prehospital transportation, management, and outcome of cardiogenic shock in Northern Norway 

      Eriksen, Anne Sofie (Master thesis; Mastergradsoppgave, 2023-10-31)
      <p>Introduction: This study aimed to determine the impact of prehospital management and transfer to a tertiary hospital on the outcome of cardiogenic shock in a rural/urban setting. <p>Methods: Patients treated for cardiogenic shock in the period of 01.01.2019 to 31.12.2021, were retrospectively analysed with regards to transportation route, time to definite treatment, prehospital and intrahospital ...

    • α1-Antichymotrypsin Complex (SERPINA3) Is an Independent Predictor of All-Cause but Not Cardiovascular Mortality in Patients Hospitalized for Chest Pain of Suspected Coronary Origin 

      Nilsen, Dennis WT; Aarsetøy, Reidun; Pønitz, Volker; Ueland, Thor; Aukrust, Pål; Michelsen, Annika Elisabet; Andersen, Trygve Brugger; Staines, Harry; Grundt, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-25)
      Introduction: SERPINA3 is an acute phase protein triggered by inflammation. It is upregulated after an acute myocardial infarction (AMI). Data on its long-term prognostic value in MI patients are scarce. We aimed to assess the utility of SERPINA3 as a prognostic marker in patients hospitalized for chest pain of suspected coronary origin. Methods: A total of 871 consecutive patients, 386 diagnosed ...

    • Mental Health Problems, General Health and Dropout in Upper Secondary School in Northern Norway: A prospective cohort study and a qualitative exploration of the dropout process 

      Goll, Charlotte Bjørnskov (Doctoral thesis; Doktorgradsavhandling, 2024-11-22)
      Health and socioeconomic inequalities are heavily correlated, and poor mental health increases the risk of exclusion from the labour market. Education is important to equalize the socioeconomic gradient, and completing upper secondary school is essential. The high dropout rates in upper secondary school are therefore of high concern. The main project “Ung vilje” was a prospective cohort study started ...

    • Increasing Mind Wandering With Accelerated Intermittent Theta Burst Stimulation Over the Left Dorsolateral Prefrontal Cortex 

      Aasen, Steffen Rygg; Drevland, Ragnhild Nicolaisen; Csifcsák, Gábor; Mittner, Matthias (Mastergradsoppgave; Master thesis, 2024-03-30)
      Mind wandering (MW) is the intentional or unintentional experience of attending to internal task-unrelated thoughts while being occupied with an external task. Even though maintaining task focus is assumed to require executive functions (EF), it is not clear how and to what extent MW and EF interact. Research has found that activity in the dorsolateral prefrontal cortex (DLPFC) is associated with ...

    • Gluconeogenesis and oxidative stress in renal proximal tubular cells 

      Klausen, David (Master thesis; Mastergradsoppgave, 2024-08-27)
      This thesis explores the hypothesis that renal gluconeogenesis has a protective role against oxidative stress in proximal tubular cells. Oxidative stress is a primary driver of pathophysiology in many diseases. This thesis reviews the fundamental factors that drive oxidative stress through electron leakage in mitochondria, highlighting tissue metabolic rate and tissue oxygenation as important ...

    • Aktivitet og måloppnåelse for «Program for distriktsmedisinsk forskning og fagutvikling» 

      Møretrø, Marte (Master thesis; Mastergradsoppgave, 2024-08-20)
      Bakgrunn og formål: «Program for distriktsmedisinsk forskning og fagutvikling», heretter kalt Programmet, ble etablert som et tiltak til økt rekruttering, stabilisering, forskning og fagutvikling hos helsepersonell i distrikt. Formålet med denne undersøkelsen er å beskrive aktiviteten til, og undersøke måloppnåelse for Programmet fra 2003-2023. Materiale og metode: Dette er en kvantitativ undersøkelse ...

    • Årsaker til lav fruktbarhet, og medias holdning til fruktbarhet i Norge 

      Domoney, Nicole Kristine Hagen; Sunniva, Tjernæs (Master thesis; Mastergradsoppgave, 2024-08-20)
      Fødselstallet i Norge er synkende. I 2013 var det samlede fruktbarhetstallet på 1.78, og nå 10 år senere, har det sunket til 1.40, som er det laveste registrerte tallet i Norge. Regjeringen har estimert et samlet fruktbarhetstall på 2.08 barn per kvinne for å reprodusere seg selv og partner. Tidligere statsminister Erna Solberg uttrykte i 2019 et behov for flere barn, så velferdsmodellen kan ...

    • Blodtrykkskontroll og blodtrykkssenkende behandling hos nyredonorer ved UNN 2016-2021. 

      Femsteinevik, Eskil (Master thesis; Mastergradsoppgave, 2024-08-19)
      Bakgrunn Det er en stadig økende etterspørsel etter nyredonorer, noe som har ført til økende interesse for langtidsrisikoen og de mulige negative helseeffektene for donorene. For å bidra til denne diskusjonen undersøker vår studie primært forskjellene i blodtrykk mellom to nyredonasjonskontroller ved nyremedisinsk poliklinikk Universitetssykehuset Nord-Norge (UNN) Tromsø, UNN Harstad og UNN ...

    • Patofysiologiske mekanismer ved akutt respirasjonssvikt.Et litteraturstudium 

      Wilhelmsen, Jacob Oppervoll (Master thesis; Mastergradsoppgave, 2024-08-19)
      Bakgrunn Prinsipielt finnes det fire aktuelle mekanismer som enkeltvis eller i samspill kan forårsake akutt respirasjonssvikt. Disse er; hypoventilasjon, diffusjonsbegrensninger, shunt og ventilasjon/perfusjon misforhold. Denne masteroppgaven er basert på et litteraturstudium hvor disse fire mekanismene blir presentert og diskutert. Material og metode Masteroppgaven baserer seg på et ...

    • Kvinnelige skiløperes erfaringer og opplevelser med bruk av hormonell prevensjon 

      Hegdahl, Sandra Nordgård (Master thesis; Mastergradsoppgave, 2024-08-09)
      Bakgrunn: En stor andel kvinnelige utøvere opplever at deres prestasjon er påvirket av menstruasjonssyklusens faser, til tross for at forskning ikke kan vise til objektive mål på hvordan prestasjonen varierer gjennom menstruasjonssyklusen. Videre er også hormonell prevensjon en faktor som påvirker de endogene hormonene hos kvinner, og kan dermed potensielt ha en innvirkning på trening og ...