Now showing items 2901-2920 of 10466

    • Higher cognitive reserve is associated with better working memory performance and working-memory-related p300 modulation 

      Gutiérrez-Zamora Velasco, Gabriela; Fernández, Thalía; Silva-Pereyra, Juan; Reynoso-Alcántara, Vicenta; Castro Chavira, Susana Angelica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-01)
      This study aims to examine how two levels of cognitive reserve, as evidenced by reading syntactic skill, modify performance and neural activity in a two-load-level (high vs. low) working memory (WM) task. Two groups of participants with different reading skills, high and low, were obtained from clustering analysis. We collected the P300 event-related potential component during the performance ...
    • Persuasion Tactics in the Implementation of f Large-Scale EHR Suites in Public Healthcare 

      Ellingsen, Gunnar; Christensen, Bente; Hertzum, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-08)
      Large-scale electronic health record (EHR) suites have the potential to cover a broad range of use needs across various healthcare domains. However, a challenge that must be solved is the distributed governance structure of public healthcare: Regional health authorities regulate hospitals, municipalities are responsible for first-line healthcare services, and general practitioners (GPs) have an ...
    • Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin 

      Svendsen, Henrik Aasrum; Meling, Torstein Ragnar; Nygaard, Vigdis; Waagene, Stein; Russnes, Hege Elisabeth Giercksky; Juell, Siri; Rogne, Siril Gudmundson; Pahnke, Jens; Helseth, Eirik; Fodstad, Øystein; Mælandsmo, Gunhild Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-06)
      Background: Malignant melanomas frequently metastasize to the brain, but metastases in the cerebellum are underrepresented compared with metastases in the cerebrum.<p> <p>Methods: We established animal models by injecting intracardially in athymic nude fox1<sup>nu</sup> mice two human melanoma cell lines, originating from a cerebral metastasis (HM19) and a cerebellar metastasis (HM86).<p> <p>Results: ...
    • Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes 

      Csengeri, Dora; Sprünker, Ngoc-Anh; Di Castelnuovo, Augusto F; Niiranen, Teemu; Vishram-Nielsen, Julie K.K.; Costanzo, Simona; Soderberg, Stefan; Jensen, Steen M; Vartiainen, Erkki; Donati, Maria Benedetta; Magnussen, Christina; Camen, Stephan; Gianfagna, Francesco; Løchen, Maja-Lisa; Kee, Frank; Kontto, Jukka; Mathiesen, Ellisiv B.; Koenig, Wolfgang; Blankenberg, Stefan; de Gaetano, Giovanni; Jørgensen, Torben; Kuulasmaa, Kari; Zeller, Tanja; Salomaa, Veikko; Iacoviello, Licia; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      Aims<p> <p>There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.<p> <p>Methods and results <p> In a community-based pooled cohort, we followed 107 845 individuals for the ...
    • Remote Monitoring of CIEDs—For Both Safety, Economy and Convenience? 

      Lappegård, Knut Tore; Moe, Frode (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-28)
      Cardiac implantable electronic devices such as pacemakers and defibrillators are increasingly monitored by systems transmitting information directly from the patient to the hospital. This may increase safety and patient satisfaction and also under certain circumstances represent an economic advantage. The review summarizes some of the recent research in the field of remote monitoring of cardiac devices.
    • Sperm mitochondrial DNA copy numbers in normal and abnormal semen analysis: A systematic review and meta-analysis 

      Popova, Daria; Bhide, Priya; D’Antonio, Francesco; Basnet, Purusotam; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-25)
      Background: Normal mature sperm have a considerably reduced number of mitochondria, which provide the energy required for progressive sperm motility. Literature suggests that disorders of sperm motility may be linked to abnormal sperm mitochondrial number and function.<p> <p>Objectives: To summarise the evidence from literature regarding the association of mitochondrial DNA copy numbers and semen ...
    • Clinical Decision Support Systems for Child Neuropsychiatric Disorders: The Time Has Come? 

      Koposov, Roman A; Frodl, Thomas; Nytrø, Øystein; Leventhal, Bennett; Sourander, Andre; Quaglini, Silvana; Molteni, Massimo; de la Iglesia Vayá, María; Ulrich Prokosch, Hans; Barbarini, Nicola; Milham, Michael Peter; Skokauskas, Norbert; Castellanos, Francisco Xavier (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-10)
      Great advances in molecular biology, genetics and imaging serve to enhance the desire to develop multi-level and multi-scale models for "personalized medicine" but they remain very challenging for high prevalence, high impact childhood onset neuropsychiatric disorders. We currently have the capacity to develop innovative, effective and efficient clinical decision support models, while also creating ...
    • Association between Diet and Xerostomia: Is Xerostomia a Barrier to a Healthy Eating Pattern? 

      Stankeviciene, Indre; Aleksejuniene, Jolanta; Puriene, Alina; Stangvaltaite-Mouhat, Lina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Objective. Xerostomia is a subjective feeling of dry mouth and is commonly observed in patients with autoimmune diseases. Our study examines the association between xerostomia and diet. Materials and Methods. The cross-sectional study includes 1405 adults from 15 Lithuanian geographical areas (52% response rate). A self-reported questionnaire inquired about xerostomia, sex, age, education, ...
    • Prior Prognostic Expectations as a Potential Predictor in Neurofeedback Training. 

      Damanskyy, Yevhen; Olsen, Alexander; Hollup, Stig Arvid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-29)
      The present study evaluated whether subjects’ expectations and neurofeedback training performance predict neurofeedback efficacy in cognitive training by controlling both factors as statistical variables. Twenty-two psychology students underwent neurofeedback training, employing beta/theta protocol to enhance beta1 power (13–21 Hz) and suppress theta (4–7 Hz) power. Neurofeedback efficacy was evaluated ...
    • Autofluorescence in freshly isolated adult human liver sinusoidal cells 

      Larsen, Anett Kristin; Simon-Santamaria, Jaione; Elvevold, Kjetil; Ericzon, Bo Gøran; Mortensen, Kim Erlend; McCourt, Peter Anthony; Smedsrød, Bård; Sørensen, Karen Kristine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      Autofluorescent granules of various sizes were observed in primary human liver endothelial cells (LSECs) upon laser irradiation using a wide range of wavelengths. Autofluorescence was detected in LAMP-1 positive vesicles, suggesting lysosomal location. Confocal imaging of freshly prepared cultures and imaging flow cytometry of non-cultured cells revealed fluorescence in all channels used. Treatment ...
    • Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway 

      Rinaldo, Christine Hanssen; Nymo, Ingebjørg Helena; Sanchez Romano, Javier; Breines, Eva Marie; Murguzur, Francisco Javier Ancin; Tryland, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Hepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we investigated anti-HEV seroprevalence in Norwegian semi-domesticated reindeer, animals in closer contact ...
    • No significant histological or ultrastructural tendinosis changes in the hamsting tendon in patients with mild to moderate osteoarthritis of the knee? 

      Ibrahim, Mustafa; Meknas, Khaled; Steigen, Sonja Eriksson; Olsen, Randi; Sernert, Ninni; Ejerhed, Lars; Kartus, Juri-Toomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-20)
      Purpose To investigate the periarticular degenerative changes of the knee joint in association with osteoarthritis (OA). More tendinosis was expected to be found in the semitendinosus tendon in patients with knee OA than in patients without knee OA.<p> Methods Samples from 41 patients were included between January 2016 and October 2017. Twenty-one patients median age 53 (33–63) years with mild ...
    • Polyphenol Intake and Epithelial Ovarian Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study 

      Londono, Catalina; Cayssials, Valerie; de Villasante, Izar; Crous-Bou, Marta; Scalbert, Augustin; Weiderpass, Elisabete; Agudo, Antonio; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Katzke, Verena; Schulze, Matthias; Palli, Domenico; Krogh, Vittorio; De Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Gram, Inger Torhild; Rylander, Charlotta; Skeie, Guri; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Sartor, Hanna; Sonestedt, Emily; Esberg, Anders; Idahl, Annika; Mahamat-Saleh, Yahya; Laouali, Nasser; Kvaskoff, Marina; Turzanski-Fortner, Renée; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-04)
      Despite some epidemiological evidence on the protective effects of polyphenol intake on epithelial ovarian cancer (EOC) risk from case-control studies, the evidence is scarce from prospective studies and non-existent for several polyphenol classes. Therefore, we aimed to investigate the associations between the intake of total, classes and subclasses of polyphenols and EOC risk in a large ...
    • Evaluation of error production in animal fluency and its relationship to frontal tracts in normal aging and mild Alzheimer's disease: A combined LDA and time-course analysis investigation 

      Itaguchi, Yoshihiro; Castro Chavira, Susana Angelica; Waterloo, Knut; Johnsen, Stein Harald; Rodríguez-Aranda, Claudia (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-12)
      Semantic verbal fluency (VF), assessed by animal category, is a task widely used for early detection of dementia. A feature not regularly assessed is the occurrence of errors such as perseverations and intrusions. So far, no investigation has analyzed the how and when of error occurrence during semantic VF in aging populations, together with their possible neural correlates. The present study aims ...
    • Introduction to the special issue: Homeostatic vs. Hedonic feeding. 

      McCutcheon, James Edgar; Williams, Diana (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
    • Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics 

      Pettersen, Veronika K.; Antunes, Luis Caetano Martha; Dufour, A; Arrieta, Marie-Claire (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-20)
      Humans have a long-standing coexistence with microorganisms. In particular, the microbial community that populates the human gastrointestinal tract has emerged as a critical player in governing human health and disease. DNA and RNA sequencing techniques that map taxonomical composition and genomic potential of the gut community have become invaluable for microbiome research. However, deriving a ...
    • Coma influence on manifest astigmatism in coma-dominant irregular corneal optics 

      Zhou, Wen; Stojanovic, Filip; Reinstein, Dan Z.; Archer, Timothy J.; Chen, Xiangjun; Feng, Yue; Stojanovic, Aleksandar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      PURPOSE:To evaluate the influence of coma on manifest refractive cylinder (MRC) in eyes with coma-dominated corneal optics and suggest alternative guidelines for surgical planning of astigmatism correction in topography-guided ablation and toric intraocular lens (IOL) exchange surgery.<p> <p>METHODS:Twelve eyes with coma-dominant corneal optics and low lenticular astigmatism were selected. The ...
    • Challenging encounters in clinical dentistry: a qualitative study investigating online reviews of patient satisfaction with Norwegian dentists 

      Larsen, Maria; Holde, Gro Eirin; Johnsen, Jan-Are Kolset (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      <b>Objective</b> <br>Mapping key themes that characterize challenging and positive encounters in dental practice using online reviews of patient satisfaction. <br><b>Materials and methods</b> <br>11,764 online patient reviews of dental encounters, consisting of an overall satisfaction rating (1–5 stars) and a free-text response, were collected from the web-site Legelisten.no. The reviews ...
    • Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study 

      Alme, Katinka Nordheim; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Ulvik, Arve; Knapskog, Anne-Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-16)
      Background - Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional and novel biomarkers of inflammation and immune modulation and their association to objectively measured sedentary behaviour in an ischemic stroke population.<p> <p>Methods ...
    • Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial 

      Grimnes, Gro; Bhoelan, Soerajja; Hindberg, Kristian; Davids, Mark; Nieuwdorp, Max; Mollnes, Tom E.; Michelsen, Annika Elisabet; Ueland, Thor; Brækkan, Sigrid K.; Hansen, John-Bjarne; Tichelaar, Ynse Ieuwe Gerardus Vladimir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-24)
      Rationale - Inflammation is present in several conditions associated with risk of venous thromboembolism. The gut microbiome might be a source of systemic inflammation and activation of coagulation, by translocation of lipopolysaccharides from gram-negative bacteria to the systemic circulation.<p> <p>Objective - To investigate whether a vancomycin-induced shift of the gut microbiome in a gram-negative ...