Now showing items 2921-2940 of 10466

    • Migration health research in Norway: a scoping review 

      Laue, Johanna; Diaz, Esperanza; Eriksen, Linda; Risør, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-05)
      <i>Aims:</i> To provide an overview of published research on migration and health conducted in Norway and identify gaps in the research field. <i>Methods:</i> Applying a scoping review methodology, we searched Medline for articles on migration health in Norway published between 2008 and 2020, and assessed them according to research topic, methodology, user-involvement and characteristics of the ...
    • Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism 

      Skjeflo, Espen Waage; Brækkan, Sigrid Kufaas; Ludviksen, Judith K; Snir, Omri; Hindberg, Kristian; Mollnes, Tom Eirik; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      The role of complement in the pathogenesis of venous thromboembolism (VTE) is unclear. We wanted to investigate (1) whether plasma complement component C5 (C5) levels are influenced by genetic variants or chronic inflammation and (2) the association between plasma C5 and risk of future VTE in a nested case-control study of 415 patients with VTE and 848 age- and sex-matched controls derived from the ...
    • Antirheumatic therapy is not associated with changes in circulating N-terminal pro-brain natriuretic peptide levels in patients with autoimmune arthritis 

      Nguyen, Thao H.P.; Fagerland, Morten; Deyab, Gia; Hjeltnes, Gunnbjørg; Hollan, Ivana; Feinberg, Mark W.; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-25)
      Background: Patients with autoimmune arthritis (AA) are at increased risk for impaired cardiac function and heart failure. This may be partly due to the effect of inflammation in heart function. The impact of antirheumatic drugs on cardiac dysfunction in AA remains controversial. Therefore, we aimed to examine effects of antirheumatic treatment on serum N-terminal pro-brain natriuretic peptide ...
    • Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition 

      Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; Beeken, Rebecca J.; Rothwell, Joseph A.; Rinaldi, Sabina; Assi, Nada; van Roekel, Eline H.; Schmidt, Julie A.; Borch, Kristin Benjaminsen; Agnoli, Claudia; Rosendahl, Ann H.; Sartor, Hanna; Huerta, José María; Tjønneland, Anne; Halkjær, Jytte; Bueno-de-Mesquita, Bas; Gicquiau, Audrey; Achaintre, David; Aleksandrova, Krasimira; Schulze, Matthias B.; Heath, Alicia K.; Tsilidis, Konstantinos K.; Masala, Giovanna; Panico, Salvatore; Kaaks, Rudolf; Fortner, Renée T.; Van Guelpen, Bethany; Dossus, Laure; Scalbert, Augustin; Keun, Hector C.; Travis, Ruth C.; Jenab, Mazda; Johansson, Mattias; Ferrari, Pietro; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-30)
      Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study.<p> <p>Methods: Targeted mass spectrometry ...
    • Treatment success with continuous positive airway pressure or mandibular advancement splints in non-severe obstructive sleep apnea: A randomized controlled clinical trial on sleep quality, health-related quality of life and clinical predictors of treatment success 

      Berg, Lars Martin (Doctoral thesis; Doktorgradsavhandling, 2022-04-04)
      Obstructive sleep apnea (OSA) is a respiratory sleep-disorder characterized by repeated breathing cessations due to pharyngeal soft tissue collapse, leading to several medical disorders and possibly premature death. Two commonly used treatment alternatives for OSA are continuous positive airway pressure (CPAP) and mandibular advancement splints (MAS). The overall aim of this randomized clinical trial ...
    • Antibiotic Use in Term and Near-Term Newborns 

      Mundal, Håkon S.; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Størdal, Ketil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      OBJECTIVES - We aimed to study whether national and local antibiotic stewardship projects have reduced the antibiotic use in newborns and to monitor potential changes in adverse outcomes.<p> <p>METHODS - In a nationwide, population-based study from Norway, we included all hospital live births from 34 weeks' gestation (n = 282 046) during 2015 to 2019. The primary outcome was the proportion of ...
    • Iohexol Plasma Clearance: Impact of Weighing the Syringe 

      Delanaye, Pierre; Melsom, Toralf; Cavalier, Etienne; Pottel, Hans; Eriksen, Bjørn Odvar; Dubourg, Laurence (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Measured glomerular filtration rate (mGFR) measurement is necessary in specific patients and/or specific clinical contexts.1–3 Plasma clearances are the preferred methods, as they are less costly and cumbersome than urinary clearances.4 The contrast medium iohexol is the most commonly used worldwide, partly for pragmatic reasons, as this marker is stable, not radioactive, and its measurement ...
    • Implementation of a shared medication list in primary care - a controlled pre-post study of medication discrepancies 

      Jøsendal, Anette Vik; Bergmo, Trine Strand; Granås, Anne Gerd (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      Background: Access to medicines information is important when treating patients, yet discrepancies in medication records are common. Many countries are developing shared medication lists across health care providers. These systems can improve information sharing, but little is known about how they afect the need for medication reconciliation. The aim of this study was to investigate whether an ...
    • Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients 

      Larsen, Stein; Goscinski, Mariusz Adam; Dueland, Svein; Steigen, Sonja Eriksson; Hofsli, Eva; Kristensen, Annette Torgunrud; Lund-Iversen, Marius; Dagenborg, Vegar Johansen; Flatmark, Kjersti; Sørbye, Halvdan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-09)
      Background - Patients with metastatic colorectal cancer (mCRC) carrying BRAF (mutBRAF) or KRAS mutation (mutKRAS) have an inferior prognosis after liver or lung surgery, whereas the prognostic role in the context of peritoneal metastasis (PM) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been less investigated.<p> <p>Methods - In total, 257 patients ...
    • Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of transphincteric perianal fistulas 

      Tencerova, Michaela; Lundby, Lilli; Norderval, Stig; Hougaard, Helene Tarri; Pedersen, Bodil Ginnerup; Kassem, Moustapha (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-24)
      Background: Injection of autologous adipose tissue (AT) has recently been demonstrated to be an efective and safe treatment for anal fstulas. AT mesenchymal stem cells (AT-MSCs) mediate the healing process, but the relationship between molecular characteristics of AT-MSCs of the injected AT and fstula healing has not been adequately studied. Thus we aimed to characterize the molecular and functional ...
    • Quantitation of linear and branched perfluoroalkane sulfonic acids (PFSAs) in women and infants during pregnancy and lactation 

      Varsi, Kristin; Huber, Sandra; Averina, Maria; Brox, Jan; Monsen, Anne-Lise Bjørke (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-24)
      Background: Per- and polyfluoroalkyl substances (PFAS) are associated with negative health effects, and exposure during fetal life and infancy are of concern. A subgroup of PFAS, linear and branched perfluoroalkane sulfonic acids (PFSA), have significant differences in biochemical reactions, bioaccumulation and potential toxic exposure effects, and data on transfer of PFSA isomers from mother to ...
    • Combined effects of plasma von Willebrand factor and platelet measures on the risk of incident venous thromboembolism 

      Edvardsen, Magnus; Hansen, Ellen-Sofie; Hindberg, Kristian; Morelli, Vania Maris; Ueland, Thor; Aukrust, Pål; Brækkan, Sigrid Kufaas; Holtet Evensen, Line; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-23)
      Plasma von Willebrand factor (VWF) and platelet reactivity are risk factors for venous thromboembolism (VTE), and VWF can promote hemostasis by interaction with platelets. In this study, we explored the combined effects of plasma VWF and platelet measures on the risk of incident VTE. A population-based nested case-control study with 403 cases and 816 controls was derived from the Tromsø Study. VWF, ...
    • Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis 

      Pinho-Gomes, Ana-Catarina; Azevedo, Luís; Copland, Emma; Canoy, Dexter; Nazarzadeh, Milad; Ramakrishnan, Rema; Berge, Eivind; Sundström, Johan; Kotecha, Dipak; Woodward, Mark; Teo, Koon K.; Davis, Barry R.; Chalmers, John; Pepine, Carl; Rahimi, Kazem (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      Purpose: To evaluate the influence of coma on manifest refractive cylinder (MRC) in eyes with coma-dominated corneal optics and suggest alternative guidelines for surgical planning of astigmatism correction in topography-guided ablation and toric intraocular lens (IOL) exchange surgery.<p> <p>Methods: Twelve eyes with coma-dominant corneal optics and low lenticular astigmatism were selected. The ...
    • Electrospinning of chloramphenicol-containing nanofibrous dressings for treatment of chronic wounds 

      Schulte Werning, Laura; Murugaiah, Anjanah; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Conference object; Konferansebidrag, 2021-03-10)
      <p><i>Background</i> An efficient treatment is crucial to overcome the delayed healing process and high infection rate in chronic wounds. Nanofibrous dressings, having a nano‐sized fiber structure, can enhance cell ingrowth and support the healing process. In addition, nanofibers can deliver active ingredients e.g. antibiotics into the wound to treat wound infection. By incorporating broad‐spectrum ...
    • Equitable access to cancer patient pathways in Norway – a national registry-based study 

      Olsen, Frank; Jacobsen, Bjarne K.; Heuch, Ivar; Tveit, Magne Kjell; Balteskard, Lise (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Background: In 2015, cancer patient pathways (CPP) were implemented in Norway to reduce unnecessary non-medical delay in the diagnostic process and start of treatment. The main aim of this study was to investigate the equality in access to CPPs for patients with either lung, colorectal, breast or prostate cancer in Norway.<p> <p>Methods: National population-based data on individual level from ...
    • One-Year Remission Rate of Chronic Headache Comparing Video and Face-to-Face Consultations by Neurologist: Randomized Controlled Trial 

      Bekkelund, Svein Ivar; Müller, Kai Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      Background: Chronic headache causing severe headache-related disability for those affected by the disease is under- or misdiagnosed in many cases and therefore requires easy access to a specialist for optimal health care management.<p> <p>Objective: The goal of the research is to determine whether video consultations are noninferior to face-to-face consultations in treating chronic headache ...
    • Jeg liker å bestemme, når jeg får bestemme - En kvalitativ studie av hvordan arbeidstakere med utviklingshemming opplever selvbestemmelse i prosessen mot arbeid på en ordinær arbeidsplass, og på den ordinære arbeidsplassen. 

      Johnsen, Andrea Berg (Master thesis; Mastergradsoppgave, 2021-05-13)
      Masteroppgaven er basert på kvalitative semi-strukturerte intervjuer med fem arbeidstakere med utviklingshemming, som jobber hele eller deler av arbeidstiden på en ordinær arbeidsplass. Problemstillingen som undersøkes er hvordan arbeidstakere med utviklingshemming opplever sin selvbestemmelse i prosessen mot arbeid på en ordinær arbeidsplass, og på den ordinære arbeidsplassen. I tillegg undersøkes ...
    • Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study 

      Myklebust, Mette Pernille; Thor, Anna; Rosenlund, Nina Benedikte; Gjengstø, Peder; Karlsdottir, Åsa; Brydøy, Marianne; Bercea, Bogdan Stefan; Olsen, Christian; Johnson, Ida; Berg, Mathilde I.; Langberg, Carl; Andreassen, Kristine; Kjellman, Anders; Haugnes, Hege Sagstuen; Dahl, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCG<sub>β</sub>). Overall, 180 patients were prospectively enrolled in the study, with serum samples collected before and after orchiectomy. We compared the use of digital droplet ...
    • M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis 

      Brix, Ninna; Glerup, Mia; Thiel, Steffen; Mistegaard, Clara Elbæk; Skals, Regitze Gyldenholm; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan Mary; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of leukaemia may be vague. The primary aim was to examine the use of lectin complement pathway proteins as markers to differentiate ALLarthropathy from JIA. The secondary aims were ...
    • An introduction to network analysis for studies of medication use 

      Askar, Mohsen Gamal Saad; Nozal Cañadas, Rafael; Svendsen, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-29)
      Background - Network Analysis (NA) is a method that has been used in various disciplines such as Social sciences and Ecology for decades. So far, NA has not been used extensively in studies of medication use. Only a handful of papers have used NA in Drug Prescription Networks (DPN). We provide an introduction to NA terminology alongside a guide to creating and extracting results from the medication ...