Det helsevitenskapelige fakultet: Recent submissions

Now showing items 3161-3180 of 10467

    • Erfaringer med økonomiske støtteordninger for tannbehandling hos personer som er behandlet for hode-halskreft 

      Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11)
      Medlemmer i Munn- og halskreftforeningen mottok et spørreskjema for å kartlegge erfaringer med økonomiske refusjonsordninger for tannbehandling og kostnader til tannbehandling hos personer som er behandlet for hode-halskreft i Norge. I tillegg kartla vi utviklingen i Folketrygdens honorartakster for tannbehandling i perioden 2015-2020, og sammenlignet honorartakstene for 2021 med takstene for ...

    • Substituting facial movements in singers changes the sounds of musical intervals 

      Laeng, Bruno; Kuyateh, Sarjo; Kelkar, Tejaswinee (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-17)
      Cross-modal integration is ubiquitous within perception and, in humans, the McGurk effect demonstrates that seeing a person articulating speech can change what we hear into a new auditory percept. It remains unclear whether cross-modal integration of sight and sound generalizes to other visible vocal articulations like those made by singers. We surmise that perceptual integrative effects should ...

    • Development of a novel beta-glucan supplemented hydrogel spray formulation and wound healing efficacy in a db/db diabetic mouse model 

      Grip, Jostein; Steene, Erik; Engstad, Rolf Einar; Hart, Jeff; Bell, Andrea; Skjærveland, Ingrid; Basnet, Purusotam; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-30)
      To relieve the severe economic and social burdens and patient suffering caused by the increasing incidence of chronic wounds, more effective treatments are urgently needed. In this study, we focused on developing a novel sprayable wound dressing with the active ingredient β-1,3/1,6-glucan (βG). Since βG is already available as the active ingredient in a commercial wound healing product provided as ...

    • Studying accelerated cardiovascular ageing in Russian adults through a novel deep-learning ECG biomarker 

      Benavente, Ernest Diez; Jimenez-Lopez, Francisco; Attia, Zachi I.; Malyutina, Sofia; Kudryavtsev, Alexander; Ryabikov, Andrey; Friedman, Paul A.; Kapa, Suraj; Voevoda, Michael; Perel, Pablo; Schirmer, Henrik; Hughes, Alun D.; Clark, Taane; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-25)
      Background: A non-invasive, easy-to-access marker of accelerated cardiac ageing would provide novel insights into the mechanisms and aetiology of cardiovascular disease (CVD) as well as contribute to risk stratification of those who have not had a heart or circulatory event. Our hypothesis is that differences between an ECG-predicted and chronologic age of participants (δage) would reflect accelerated ...

    • Rewarming With Closed Thoracic Lavage Following 3-h CPR at 27°C Failed to Reestablish a Perfusing Rhythm 

      Nivfors, Joar O.; Mohyuddin, Rizwan; Schanche, Torstein; Nilsen, Jan Harald; Valkov, Sergei; Kondratiev, Timofei V.; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
      Introduction: Previously, we showed that the cardiopulmonary resuscitation (CPR) for hypothermic cardiac arrest (HCA) maintained cardiac output (CO) and mean arterial pressure (MAP) to the same reduced level during normothermia (38°C) vs. hypothermia (27°C). In addition, at 27°C, the CPR for 3-h provided global O2 delivery (DO2) to support aerobic metabolism. The present study investigated if rewarming ...

    • Liberal versus Modified Intraoperative Fluid Management in Abdominal-flap Breast Reconstructions. A Clinical Study 

      Sjöberg, Thomas; Numan, Anmar; De Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09)
      Background: The outcome of reconstructive microsurgery is influenced by the intraoperative anesthetic regimen. The aim of this study was to compare the impact on the intra- and postoperative complication rates of our modified fluid management (MFM) protocol with a previously used liberal fluid management protocol in abdominal-flap breast reconstructions.<p> <p>Methods: This retrospective study ...

    • Who keeps on working? The importance of resilience for labour market participation 

      Berthung, Espen; Gutacker, Nils; Friborg, Oddgeir; Abelsen, Birgit; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      Background<p> <p>It is widely recognized that individuals’ health and educational attainments, commonly referred to as their human capital, are important determinants for their labour market participation (LMP). What is less recognised is the influence of individuals’ latent resilience traits on their ability to sustain LMP after experiencing an adversity such as a health shock.<p> Aim<p> We ...

    • Knowledge versus education in the margins: An indigenous and feminist critique of education 

      Svalastog, Anna Lydia; Wilson, Shawn; Hansen, Ketil Lenert (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-11)

    • Female Mice Reaching Exceptionally High Old Age Have Preserved 20S Proteasome Activities 

      Martínez de Toda, Irene; Rattan, Suresh IS; De la Fuente, Mónica; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-31)
      Oxidized, damaged and misfolded proteins accumulate during aging and contribute to impaired cell function and tissue homeodynamics. Damaged proteins are degraded by cellular clearance mechanisms like the 20S proteasome. Aging relates to low 20S proteasome function, whereas long-lived species show high levels. However, contradictory results exist depending on the tissue or cell type and it is ...

    • Irradiated tumor fibroblasts avoid immune recognition and retain immunosuppressive functions over natural killer cells 

      Yang, Nannan; Lode, Kristin; Berzaghi, Rodrigo; Islam, Md Ashraful; Martinez, Inigo Zubiavrre; Hellevik, Turid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-22)
      Recent studies have demonstrated that radiotherapy is able to induce anti-tumor immune responses in addition to mediating direct cytotoxic effects. Cancer-associated fibroblasts (CAFs) are central constituents of the tumor stroma and participate actively in tumor immunoregulation. However, the capacity of CAFs to influence immune responses in the context of radiotherapy is still poorly understood. ...

    • Cerebrospinal fluid markers for synaptic function and Alzheimer type changes in late life depression 

      Siafarikas, Nikias Ioannis; Kirsebom, Bjørn-Eivind; Srivastava, Deepak P; Eriksson, Cecilia Magdalena; Auning, Eirik; Hessen, Erik; Selbæk, Geir; Blennow, Kaj; Aarsland, Dag; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-13)
      To explore markers for synaptic function and Alzheimer disease (AD) pathology in late life depression (LLD), predementia AD and normal controls (NC). A cross-sectional study to compare cerebrospinal fluid (CSF) levels of neurogranin (Ng), Beta-site amyloid-precursor-protein cleaving enzyme1 (BACE1), Ng/BACE1 ratio and Amyloid-β 42/40 ratio, phosphorylated-tau and total-tau in LLD with (LLD AD) or ...

    • The effects of virutal reality on procedural pain and anxiety in pediatrics: A systematic review and meta-analysis 

      Nordgård, Rikke Kathrine; Låg, Torstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-15)
      Distraction and procedural preparation techniques are frequently used to manage pain and anxiety in children undergoing medical procedures. An increasing number of studies have indicated that Virtual Reality (VR) can be used to deliver these interventions, but treatment effects vary greatly. The present study is a systematic review and meta-analysis of studies that have used VR to reduce procedural ...

    • Pragmatiske studier – hva er det? 

      Lyngbakken, Magnus Nakrem; Paulsen, Aksel; Sethupathy, Ashwini; Hesselberg, Øyvind; Grimsgaard, Sameline; Hagen, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-11)
      Konseptet pragmatiske studier ble foreslått av Schwartz og Lellouch i 1967 og problematiserte to viktige aspekter ved utprøving av ny behandling, nemlig forståelse og beslutning (1). Tradisjonelle forklarende effektstudier (explanatory trials) har som mål å øke vår forståelse ved å vise om en behandling virker per se, ofte under optimale forhold med nøye utvalgte studiedeltakere og utfallsmål. ...

    • Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes: Federated Meta-Analysis of 28 Prospective Studies Including 956,122 Participants 

      Pastorino, Silvia; Bishop, Tom; Sharp, Stephen J.; Pearce, Matthew; Akbaraly, Tasnime; Barbieri, Natalia B.; Bes-Rastrollo, Maira; Beulens, Joline W.J.; Chen, Zhengming; Du, Huaidong; Duncan, Bruce B.; Goto, Atsushi; Härkänen, Tommi; Hashemian, Maryam; Kromhout, Daan; Järvinen, Ritva; Kivimaki, Mika; Knekt, Paul; Lin, Xu; Lund, Eiliv; Magliano, Dianna; Malekzadeh, Reza; Martínez-González, Miguel Ángel; O’donoghue, Gráinne; O’gorman, Donal; Poustchi, Hossein; Rylander, Charlotta; Sawada, Norie; Shaw, Jonathan E.; Schmidt, Maria; Soedamah-Muthu, Sabita S.; Sun, Liang; Wen, Wanqing; Wolk, Alicja; Shu, Xiao-Ou; Zheng, Wei; Wareham, Nicholas J.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-07)
      The association between fish consumption and new-onset type 2 diabetes is inconsistent and differs according to geographical location. We examined the association between the total and types of fish consumption and type 2 diabetes using individual participant data from 28 prospective cohort studies from the Americas (6), Europe (15), the Western Pacific (6), and the Eastern Mediterranean (1) comprising ...

    • Bacterial membrane-derived vesicles attenuate vancomycin activity against methicillin-resistant staphylococcus aureus 

      Kumaraswamy, Monika; Wiull, Kamilla; Joshi, Bishnu; Sakoulas, George; Kousha, Armin; Vaaje-Kolstad, Gustav; Johannessen, Mona; Hegstad, Kristin; Nizet, Victor; Askarian, Fatemeh (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
      Methicillin-resistant Staphylococcus aureus (MRSA) has evolved numerous antimicrobial resistance mechanisms and is identified as a serious public health threat by the World Health Organization and U.S. Centers for Disease Control and Prevention. The glycopeptide vancomycin (VAN) remains a cornerstone of therapy for severe MRSA infections despite increasing reports of therapeutic failure in hospitalized ...

    • The Norwegian childhood cancer biobank 

      Hermansen, Johanne Uthus; Wojcik, Dorota; Robinson, Nina; Pahnke, Jens; Haugland, Hans Kristian; Jamtøy, Ann-Helen; Flægstad, Trond; Halvorsen, Hanne; Lund, Bendik; Baumbusch, Lars Oliver; Munthe-Kaas, Monica Cheng (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
      Background - The rapidly expanding era of “omics” research is highly dependent on the availability of quality-proven biological material, especially for rare conditions such as pediatric malignancies. Professional biobanks provide such material, focusing on standardized collection and handling procedures, distinctive quality measurements, traceability of storage conditions, and accessibility. For ...

    • Sunscreens With High Versus Low Sun Protection Factor and Cutaneous Squamous Cell Carcinoma Risk: A Population-Based Cohort Study 

      Lergenmuller, Simon; Ghiasvand, Reza; Robsahm, Trude Eid; Green, Adèle C.; Lund, Eiliv; Rueegg, Corina Silvia; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-11)
      Evidence on sunscreen use and cutaneous squamous cell carcinoma (cSCC) risk is limited. Most studies have not taken sun protection factor (SPF) into consideration and used nonusers of sunscreen as the reference group. Nonusers are likely a priori at lower cSCC risk than users. No study has investigated the effect of high- versus low-SPF sunscreens on cSCC, appropriately adjusting for time-varying ...

    • The prevalence of potentially traumatic events in the seventh survey of the population-based Tromsø study (Tromsø 7) 

      Thimm, Jens; Rognmo, Kamilla; Rye, Marte; Flåm, Anna Margrete; Næss, Eva Therese; Skre, Ingunn; Wang, Catharina Elisabeth Arfwedson (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-20)
      Aims: Potentially traumatic events (PTEs) can have detrimental consequences for an individual’s physical and mental health. Exposure to PTEs is therefore increasingly assessed in population-based studies. Consistent with this trend, the most recent wave of the longitudinal population-based Tromsø study (Tromsø 7) in Northern Norway included a list of PTEs. The aim of the present study was to describe ...

    • Context and general practitioner decision-making - a scoping review of contextual influence on antibiotic prescribing 

      Al-Azzawi, Resha; Halvorsen, Peder Andreas; Risør, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-15)
      Background - How contextual factors may influence GP decisions in real life practice is poorly understood. The authors have undertaken a scoping review of antibiotic prescribing in primary care, with a focus on the interaction between context and GP decision-making, and what it means for the decisions made.<p> <p>Method - The authors searched Medline, Embase and Cinahl databases for English ...

    • Peer Support for People Living With HIV: A Scoping Review 

      Øgård-Repål, Anita; Berg, Rigmor; Fossum, Mariann (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-23)
      Peer support for people living with HIV has gained increasing traction and is considered a way to take an active role in self-management. The existing research examining peer support interventions has reported promising evidence of the benefits of peer support. The purpose of our scoping review was to describe research on peer support for people living with HIV. We included 53 studies and sorted ...