Now showing items 3521-3540 of 10469

    • Communication and information needs about complementary and alternative medisine: a qualitative study of parents of children with cancer 

      Stub, Trine; Quandt, Sara A.; Kristoffersen, Agnete E.; Jong, Miek C.; Arcury, Thomas A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)
      Background - Many parents choose support such as Complementary and Alternative Medicine (CAM) for themselves and their children who have cancer. The aim of this paper is to describe, how parents who have children with cancer communicated with conventional health care providers about CAM, and what types and sources of information they would like to receive about CAM when the child was ill.<p> <p>Method ...
    • Preservation of person-centered care through videoconferencing for patient follow-up during the covid-19 pandemic:case study of a multidisciplinary care team 

      Silsand, Line; Severinsen, Gro-Hilde; Berntsen, Gro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-05)
      Background: The Patient-Centered Team (PACT) focuses on the transitional phase between hospital and primary care for older patients in Northern Norway with complex and long-term needs. PACT emphasizes a person-centered care approach whereby the sharing of power and the patient’s response to “What matters to you?” drive care decisions. However, during the COVID-19 pandemic, videoconferencing was the ...
    • Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury 

      Dukay, Brigitta; Walter, Fruzsina; Vigh, Judit; Barabasi, Beata; Hajdu, Petra; Balassa, Tamas; Migh, Ede; Kincses, Andras; Hoyk, Zsofia; Szogi, Titanilla; Borbely, Emoke; Csoboz, Balint; Horvath, Peter; Fulop, Livia; Penke, Botond; Vigh, Laszlo; Deli, Maria; Santha, Mikos; Toth, Melinda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-10)
      Background - Heat-shock protein B1 (HSPB1) is among the most well-known and versatile member of the evolutionarily conserved family of small heat-shock proteins. It has been implicated to serve a neuroprotective role against various neurological disorders via its modulatory activity on inflammation, yet its exact role in neuroinflammation is poorly understood. In order to shed light on the exact ...
    • Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 

      Pedersen, Elisabeth; Garcia, Beate Hennie; Halvorsen, Kjell H.; Eggen, Anne Elise; Schirmer, Henrik; Waaseth, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-21)
      Background - Adherence to clinical practice guidelines for coronary heart disease (CHD) reduces morbidity, mortality and treatment costs. We aimed to describe and compare adherence to prescription guidelines for persons with CHD, and explore its association with treatment goal achievement.<p> <p>Method - We included all participants reporting myocardial infarction, angina, percutaneous coronary ...
    • Sámi and Norwegian nurses’ perspectives on nursing care of Sámi patients: a focus group study on culturally safe nursing 

      Engnes, Janne Isaksen; Sivertsen, Nina; Bongo, Berit Andersdatter; Mehus, Grete (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
      Sámi people report less satisfaction with healthcare services than the majority population in Norway, and report that they seldom encounter culturally adapted health services. This study investigates Sámi and Norwegian nurses’ perspectives on culturally respectful and appropriate caring for Sámi patients in northern Norway. Six focus groups were conducted: three with Sámi-speaking nurses (n = 13) ...
    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-14)
      <p>Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with ...
    • Rat ultrasonic vocalizations and novelty-induced social and non-social investigation behavior in a seminatural environment 

      Heinla, Indrek; Chu, Xi; Ågmo, Anders j; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-03)
      Although rats are known to emit ultrasonic vocalizations (USVs), it remains unclear whether these calls serve an auditory communication purpose. For USVs to be part of communication, the vocal signals will need to be a transfer of information between two or more conspecifics, and with the possibility to induce changes in the behavior of the recipient. Therefore, the aim of our study was to investigate ...
    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...
    • Transcriptome profiling of staphylococcus aureus associated extracellular vesicles reveals presence of small RNA-cargo 

      Joshi, Bishnu; Singh, Bhupender; Nadeem, Aftab; Askarian, Fatemeh; Wai, Sun Nyunt; Johannessen, Mona; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      Bacterial extracellular vesicles (EVs) have a vital role in bacterial pathogenesis. However, to date, the small RNA-cargo of EVs released by the opportunistic pathogen Staphylococcus aureus has not been characterized. Here, we shed light on the association of small RNAs with EVs secreted by S. aureus MSSA476 cultured in iron-depleted bacteriologic media supplemented with a subinhibitory dosage of ...
    • Moderate-to-vigorous physical activity modifies the relationship between sedentary time and sarcopenia: the Tromsø Study 2015–2016 

      Johansson, Jonas; Morseth, Bente; Scott, David; Strand, Bjørn Heine; Hopstock, Laila Arnesdatter; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      <p>Background: Sarcopenia is an age-related muscle disease primarily characterized by reductions in muscle strength that increases the risk of falls, fractures, cognitive impairment, and mortality. Exercise is currently preferred in prevention and treatment, but it is unknown how different habitual physical activity and sedentary behaviour patterns associate with sarcopenia status. The purpose of ...
    • Optimization of the use of PrepFiler Express™ Forensic DNA extraction kit lysis buffer discard for mRNA profiling 

      Hamnevoll, Kari (Mastergradsoppgave; Master thesis, 2021-06-01)
      mRNA profiling for body fluid or tissue type identification is able to provide circumstantial information alongside DNA profiles from biological material found at a crime scene. To solve the challenge of material limitation in body fluid identification, studies have successfully developed mRNA profiles of RNA extracted from lysis buffer discard of DNA-extraction. It would be interesting to examine ...
    • High Palmitate Alters Glutathione Redox During Severe Oxidant Stress in the Heart; An Evaluation of Altered Glutathione Redox Environment on Cardiac Function and Mitochondrial Energetics. 

      Sepehrara, Ramin (Mastergradsoppgave; Master thesis, 2021-05-18)
      When the heart is under stress, e.g. ischemia-reperfusion (IR), it produces an enormous amount of reactive oxygen species (ROS). Glutathione, which is an endogenous antioxidant derived from the ‘nicotinamide adenine dinucleotide hydrogen’ (NADH) of the ‘tricarboxylic acid’ cycle, can fight against this oxidative stress to balance the redox environment, and convert the produced ROS to H2O. In this ...
    • User involvement in adolescents’ mental healthcare: a systematic review 

      Viksveen, Petter; Bjønness, Stig Erlend; Cardenas, Nicole Elizabeth; Game, Julia Rose; Berg, Siv Hilde; Salamonsen, Anita; Storm, Marianne; Aase, Karina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      More than one out of ten adolescents suffer from mental illness at any given time. Still, there is limited knowledge about their involvement in mental healthcare. Adolescents have the right to be involved in decisions affecting their healthcare, but limited research focuses on their engagement and decision-making. Therefore, this systematic review aims to explore the existing experiences with, the ...
    • Sexual incentive motivation and male and female copulatory behavior in female rats given androgen from postnatal day 20 

      Chu, Xi; Snoeren, Eelke; Södersten, Per; Ågmo, Anders j (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-12)
      Masculinization and feminization of rat sexual behavior has been supposed to occur during a short postnatal period. However, much data have made it evident that these processes may continue until adolescence. In the present study, we evaluated whether androgen treatment of females from postnatal day 20 and onwards could alter sexual motivation and behavior in a male direction. Juveniles were ...
    • Determinants of caregiver satisfaction with child neurodevelopmental assessment in neuropaediatric clinics 

      Kjærandsen, Katarina; Brøndbo, Per Håkan; Halvorsen, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-12)
      Background - In addition to patient evaluations, caregiver evaluations and experiences are important indicators of the quality of health services. The aim of this study was to examine determinants of caregiver satisfaction with and perceived benefit of child neurodevelopmental assessment in neuropaediatric clinics.<p> <p>Methods - The study was conducted among caregivers of children and adolescents ...
    • Ionizing radiation curtails immunosuppressive effects from cancer-associated fibroblasts on dendritic cells 

      Berzaghi, Rodrigo; Tornaas, Stian; Lode, Kristin; Hellevik, Turid; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Cancer-associated fibroblasts (CAFs) participate actively in tumor development and affect treatment responses, by among other mechanisms, promoting an immunosuppressive tumor microenvironment. In contrast to normal fibroblasts, reactive CAFs secrete a myriad of immunomodulatory soluble factors at high levels, i.e. growth factors, cytokines, and chemokines, which directly influence tumor immunity and ...
    • Detection of quebec polyomavirus dna in samples from different patient groups 

      Prezioso, Carla; Van Ghelue, Marijke; Pietropaolo, Valeria; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
      Polyomaviruses infect many species, including humans. So far, 15 polyomaviruses have been described in humans, but it remains to be established whether all of these are genuine human polyomaviruses. The most recent polyomavirus to be detected in a person is Quebec polyomavirus (QPyV), which was identified in a metagenomic analysis of a stool sample from an 85-year-old hospitalized man. We used PCR ...
    • High expression of microRNA‑126 relates to favorable prognosis for colon cancer patients 

      Selven, Hallgeir; Rasmussen Busund, Lill-Tove; Bremnes, Roy M.; Andersen, Sigve; Kilvær, Thomas Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-05)
      miR-126 has been identified both as a tumor suppressor and an oncogene in different types of cancer. The aim of this study was to investigate the prognostic impact of miR-126-expression in colon cancer patients. Tumor tissue from 452 patients operated for stage I–III colon cancer was retrospectively collected and tissue microarrays were constructed. miR-126 expression was evaluated by in situ ...
    • Ticket To Ride: A Longitudinal Journey to Work Engagement and Health in the JD-R model 

      Langseth-Eide, Benedicte; Vittersø, Joar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-19)
      The present study addresses one of the limitations of the JD-R model, namely, that analyses of the outcomes of the motivational process have largely focused on organizational outcomes and have neglected to investigate the associations between job resources, work engagement and health-related outcomes. Specifically, the aim of this paper is to show that health-related indicators may be outcomes of ...
    • Fluoride in the drinking water and dental caries experience by tooth surface susceptibility among adults 

      Stangvaltaite-Mouhat, Lina; Puriene, Alina; Stankeviciene, Indre; Aleksejūnienė, Jolanta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-04)
      <p>Background: Dental caries is the most prevalent non-communicable health condition globally. The surface-based susceptibility hierarchy indicates that surfaces in the same group have similar susceptibility to caries, where the most susceptible group consists of occlusal surfaces of first molars and buccal surfaces of lower first molars, and the least susceptible surfaces are smooth and proximal ...