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norskDet helsevitenskapelige fakultet: Recent submissions
Now showing items 3601-3620 of 10469
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Physical capability, physical activity, and their association with femoral bone mineral density in adults aged 40 years and older: The Tromsø study 2015–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-16)Summary: Since muscles can influence bone growth and vice versa, we examined if level of physical activity and physical capability tests can predict areal bone mineral density (aBMD). Both high activity level and good test performance were associated with higher aBMD, especially in women. <p> <p>Introduction: Muscle influences bone formation and vice versa. Tests of physical capability and level ... -
Da laben hun tilhører stengte dørene, flyttet Solveig babyforskningen sin til Zoom
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-08)Det så mørkt ut for Solveig Flatebøs doktorgradsarbeid da Norge erklærte unntakstilstand i mars i fjor. Så fikk hun en idé som gjorde forskningen mye lettere å gjennomføre. -
Complete Genome Sequences of 12 Quinolone-Resistant Escherichia coli Strains Containing qnrS1 Based on Hybrid Assemblies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-28)In total, 12 quinolone-resistant <i>Escherichia coli</i> (QREC) strains containing <i>qnrS1</i> were submitted to long-read sequencing using a FLO-MIN106 flow cell on a MinION device. The long reads were assembled with short reads (Illumina) and analyzed using the MOB-suite pipeline. Six of these QREC genome sequences were closed after hybrid assembly. -
Clinical Lipidomics: Effects of Vitamin D in Human Adipose Tissue
(Master thesis; Mastergradsoppgave, 2021-05-10)Vitamin D is vital for calcium homeostasis and skeletal health, has immunomodulatory effects and is involved in the regulation of differentiation and proliferation of many different cell types. Adipose tissue is an important metabolic organ and a major organ for vitamin D storage. Though, the role of vitamin D and its function in adipose tissue is not fully explored. This thesis applies a solvent ... -
Molecular modelling of interactions between antipsychotic drugs and receptors mediating antipsychotic effects and important side effects
(Master thesis; Mastergradsoppgave, 2021-05-10)Dopamine and serotonin are two neurotransmitters that exert their actions through mediation of dopaminergic and serotonergic receptors respectively. The receptors in focus in the current study, are the dopamine D2 and serotonin 5-HT2A receptors. Common for both receptors is that they are class A G-protein-coupled receptors consisting of seven transmembrane helices embedded in the lipid membrane of ... -
Mest meningsfylte dager. En kvalitativ oppgave om sykepleieres opplevelse av eget arbeid i Psykisk helse og TSB
(Master thesis; Mastergradsoppgave, 2020-06-09)Tema: Arbeidet til sykepleiere i feltet Psykisk helse og TSB Metode: Kvalitativ forskningsmetode, der semistrukturerte intervju ble utført. I utførelsen var det brukt lydopptak, som senere ble transkribert. Analyse: Malteruds (2017) STC Hensikten med studien var å få et innblikk i sykepleiere opplevelse av eget arbeid, når de arbeidet på en sengepost i spesialisthelsetjenesten. Resultatene viste at ... -
Forskningsfeltet innvandrerhelse i Norge – en litteraturstudie
(Master thesis; Mastergradsoppgave, 2019-06-05)Innledning: Migrasjon er relatert til helse i et komplekst samspill. Det er utfordringer knyttet til enkelte helseproblemer og til tilgjengelighet av helsetjenester for enkelte innvandrere. Forskningsaktiviteten innen innvandrerhelse er økende, men veksten er ustrukturert. Økt fokus kan videreføre arbeidet for likeverdige helsetjenester på en evidensbasert måte hvis forskningsfeltet systematiseres. ... -
Potential candidates for ECPR in the catchment area of the University hospital in North Norway
(Master thesis; Mastergradsoppgave, 2019-06-03)Introduction: Some studies report increased survival from out of hospital cardiac arrest (OHCA) with extracorporeal cardiopulmonary resuscitation (ECPR), but the survival rates vary and heterogeneous study populations complicate comparison between studies. Aim: The purpose of this study was to find potential ECPR candidates among all OHCA cases in the catchment area of the University Hospital of ... -
En perioperativ infusjon av GLP-1 forbedrer perifer insulinsensitivitet etter kirurgi
(Master thesis; Mastergradsoppgave, 2018-06-03)Bakgrunn: Postoperativ insulinresistens er assosiert med flere komplikasjoner, og behandling reduserer risiko. Inkretin-analogen GLP-1 forbedrer glykemisk kontroll, uten risiko for skadelig hypoglykemi, og kan potensielt øke postoperativ insulinsensitivitet i perifert vev samt redusere hepatisk glukoseutskillelse. Vi ønsket å finne ut av om en perioperativ infusjon av GLP-1 forbedrer insulinsensitiviteten ... -
Hvordan radiologiske undersøkelser påvirker pasientflyt i akuttmottaket – en studie før og etter innføring av overlege i akuttmottak
(Master thesis; Mastergradsoppgave, 2019-06-02)Innledning: Ventetid på radiologiske undersøkelser er en viktig årsak til store deler av ventetiden i akuttmottaket. Overfylte akuttmottak er et problem i hele verden, og å øke den legefaglige kompetansen i akuttmottaket er et tiltak som har vist seg å være nyttig i andre land. Det er derimot ingen som har sett på hva det spesifikt har gjort med ventetidene til radiologiske undersøkelser. Metode: ... -
Natalizumab ved Multippel Sklerose. Praksis og erfaring fra Nevrologisk avdeling, Nordlandssykehuset i Bodø
(Master thesis; Mastergradsoppgave, 2019-06-02)Bakgrunn: Natalizumab (Tysabri®) er et immunmodulerende legemiddel som brukes som behandling mot multippel sklerose (MS). Det tilbys vanligvis som andrelinjebehandling, men enkelte pasienter med aggressiv sykdom starter direkte med natalizumab. Det er generelt et godt tolerert og effektivt legemiddel, men er assosiert med enkelte alvorlige bivirkninger, som den sjeldne tilstanden progressiv ... -
Health and wellbeing in Norway: Population norms and the social gradient
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)Measures of health-related quality of life are important in health technology assessments, and useful when analysing health inequalities across population sub-groups. This paper provides population norms on health and wellbeing in Norway based on two waves of a comprehensive health survey: Wave 6 of The Tromsø Study conducted in 2007/08 (N = 12,981) and Wave 7 conducted in 2015/16 (N = 21,083). By ... -
Evaluering av In vitro metode for demineralisering av rotoverflaten
(Mastergradsoppgave; Master thesis, 2020-05-20)Bakgrunn: Stadig flere eldre beholder sine egne tenner i høy alder. Blant de utfordringene som hyppig ses er blottlagte rotoverflater. Rotoverflatene er sårbare for kariesangrep og erosjoner. Målet for studien var å skape demineralisering in vitro på rotoverflater med et utvalg av fire syreløsninger. Vi skulle beskrive hvordan eventuelle demineraliseringer visuelt artet seg på rotoverflaten, og ... -
Knowledge of, compliance with and attitudes towards, infection control routines in dental practice: a survey among dental students and dental faculty members in North-West Russia
(Mastergradsoppgave; Master thesis, 2020-05-20)Infections are among the most significant healthcare problems in terms of the global perspective. Its increasing burden on healthcare settings may lead to a higher prevalence of antibiotic resistance, increased morbidity, and mortality among the patients who admit to health care institutions. Several antibiotic-resistant bacteria, including Methicillin Resistant Staphylococcus Aureus (MRSA), which ... -
In vitro micro-CT analyse av demineraliseringslesjoner på emaljeoverflaten
(Mastergradsoppgave; Master thesis, 2020-05-20)Målsetting: Målet med dette masterforsøket er å danne demineraliseringslesjoner som ligner på initialkaries ved hjelp av 4 ulike syreløsninger på emaljeoverflaten in vitro, og deretter sammenlikne bildene utfra de diagnostiske kriteriene, definert under, for å se hvilken som gir det beste resultatet. Metode: 40 tenner ble samlet inn fra UTK og TkNN, hvor deretter 12 tenner ble randomisert valgt ut ... -
Potential effect of airborne-particle abrasion (APA) on stainless steel and ceramic bracket base volume
(Mastergradsoppgave; Master thesis, 2020-05-20)Background: Bracket failure due to loss of adhesion is common and influences treatment time and patient comfort in orthodontic practice. This pilot study is focused on a widely used adjunctive method for bracket recycling -Airborne-Particle Abrasion (APA) and its impact on the retentive mesh pad volume and surface area in two types of brackets. Objectivities: To explore potential loss of retention ... -
Comparing apical bacterial leakage using two different obturation techniques in human upper incisors: An in vitro pilot study
(Mastergradsoppgave; Master thesis, 2020-05-19)The materials and techniques for root canal obturation is critical for treatment success. Cold lateral condensation is a widely used obturation technique, but core carrier techniques requiring heat has been developed to overcome disadvantages with the cold obturation techniques. GuttaCore is a relatively new and unstudied core carrier technique in vitro. The bacterial leakage test has been regarded ... -
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-18)Although oral drug delivery is the preferred administration route and has been used for centuries, modern drug discovery and development pipelines challenge conventional formulation approaches and highlight the insufficient mechanistic understanding of processes critical to oral drug absorption. This review presents the opinion of UNGAP scientists on four key themes across the oral absorption ... -
Survey of European neurosurgeons’ management of unruptured intracranial aneurysms: inconsistent practice and organization
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-01)Background - The discovery of an unruptured intracranial aneurysm creates a dilemma between observation and treatment. Neurosurgeons’ routines for risk assessment and treatment decision-making are unknown. The position of evidence-based medicine in European neurosurgery is considered to be weak, high-grade guidelines do not exist and variations between institutions are probable. We aimed to explore ... -
Systematic identification and stratification of help-seeking school-aged youth with mental health problems: a novel approach to stage-based stepped-care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-18)We investigated whether a novel visitation model for school-aged youth with mental health problems based on a stage-based stepped-care approach facilitated a systematic identification and stratification process without problems with equity in access. The visitation model was developed within the context of evaluating a new transdiagnostic early treatment for youth with anxiety, depressive symptoms, ...
