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norskDet helsevitenskapelige fakultet: Recent submissions
Now showing items 4301-4320 of 10619
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Exploration of rabbit integrin β3 as a possible immune-tolerizing agent to prevent foetal and neonatal alloimmune thrombocytopenia.
(Mastergradsoppgave; Master thesis, 2020-08-07)Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease caused by the production of antibodies by the mother to the platelets of the foetus. The alloimmune response is caused by a P33L substitution in the Human Platelet Antigen-1a (HPA-1a) in a homo- or heterozygous HPA-1a foetus, in a homozygous HPA-1b+ mother. Maternal antibodies are produced by activated HPA-1a specific T-cells able ... -
Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-27)<i>Background</i> - Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs; liver resident macrophages) form the body’s most effective scavenger cell system for the removal of harmful blood-borne substances, ranging from modified self-proteins to pathogens and xenobiotics. Controversies in the literature regarding the LSEC phenotype pose a challenge when determining distinct functionalities ... -
C-reactive protein and its associations with сardiometabolic risk factors and echocardiographic indicators of heart failure: results of “Know your heart” study in Arkhangelsk
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09)<p><i>Цель - </i>Оценка связи высокочувствительного С-реактивного белка (вчСРБ) с кардиометаболическими и эхокардиографическими (ЭхоКГ) индикаторами сердечной недостаточности (СН) среди взрослого населения Северного региона России. <p><i>Материал и методы - </i>Поперечное исследование «Узнай свое сердце» проведено в 2015–2017 гг. на случайной выборке общего населения г. Архангельска в возрасте 35–69 ... -
Student characteristics associated with dominant approaches to studying: Comparing a national and an international sample
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-11)<p><i>Background - </i>Productive approaches to studying (deep and strategic learning) are associated with a variety of favourable academic outcomes, and may be of particular importance for students in multifaceted and complex disciplines such as occupational therapy. <p><i>Aim - </i>To explore associations between student characteristics and their dominant approaches to studying in two samples of ... -
ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-29)<p><i>Background and aims - </i>Activated leukocyte cell adhesion molecule (ALCAM) is upregulated during inflammation and involved in transmigration of leukocytes and T-cell activation. We hypothesized that ALCAM might be associated with recurrent events in patients with acute coronary syndromes (ACS). <p><i>Methods - </i>ALCAM was measured in serum obtained on admission, at discharge, 1 month and ... -
Sterke inntrykk og tøffe opplevelser i arbeidshverdagen - Må man være hardhudet for å kunne jobbe som operasjonssykepleier?
(Mastergradsoppgave; Master thesis, 2020-11-02)En kvalitativ studie om hvordan operasjonssykepleiere erfarer å stå i kritiske situasjoner på operasjonsavdelingen, og hvilke faktorer de mener vil kunne fremme mestring ved slike situasjoner -
Preoperativ antisepsis på operasjonsstuen - Hvilke desinfeksjonsmiddel og metoder anbefales i eksisterende forskningslitteratur?
(Mastergradsoppgave; Master thesis, 2020-11-02)Preoperativ antisepsis er et viktig tiltak for å redusere risikoen for postoperative sårinfeksjoner. Hva som er beste desinfeksjonsmiddel og fremgangsmåte for påføring av desinfeksjonsmiddel er et uoppklart tema. Det ble gjort en litteraturstudie med systematisk tilnærming. Målet var å finne oppsummert forskningskunnskap og fagfellevurderte enkeltstudier som undersøker hva som er beste desinfeksjonsmiddel ... -
Transcranial Direct Current Stimulation as a memory enhancer in healthy participants and patients with Alzheimer`s disease
(Doctoral thesis; Doktorgradsavhandling, 2020-12-18)<p>The aim of this thesis was to investigate the effects of transcranial direct current stimulation (tDCS) as a memory enhancer in Alzheimer’s disease patients and healthy individuals. In addition, we wanted to study how verbal memory functions are related to hippocampus subfield volumes. <p>This thesis consists of three reports, in which two of the reports (I and II) aimed to study the effects of ... -
Suicide among Sámi – Cultural meanings of suicide and interventions for suicide prevention in Nordic parts of Sápmi
(Doctoral thesis; Doktorgradsavhandling, 2020-12-17)<p><i>Background:</i> In suicidological research, it is well known that suicide rates differ, sometimes to a great extent, between countries, sexes, religious and ethnic populations. It has been suggested that in-depth exploration of social, cultural, contextual and historical perspectives on suicide is needed to explain this, and increase efficacy of prevention efforts. Sámi are the Indigenous ... -
Perinatal mortality and its association with antenatal care utilization in the Republic of Georgia
(Doctoral thesis; Doktorgradsavhandling, 2020-12-11)<p><i>Background:</i> Despite recent achievements, perinatal mortality (PM) rates remain high worldwide, especially in low-income countries (>30 per 1000 births). PM is defined as the death of a fetus/livebirth between 22 completed weeks of gestation and the first 7 days of life. Simple, non-invasive interventions could reduce PM rates, since most deaths are caused by preventable conditions. Adequate ... -
Ikke-invasiv prenatal testing (NIPT) for kjønnsbestemmelse av foster. Metodevurdering
(Research report; Forskningsrapport, 2016-12)X‐bundne recessive sykdommer er alvorlige arvelige sykdommer som hovedsakelig rammer gutter. Når en kvinne som er bærer av en X‐bundet recessiv sykdom føder barn, kan hun få en frisk jente, en frisk jente som er bærer som sin mor, en frisk gutt, eller en gutt som har den X‐bundne recessive sykdommen. Dagens praksis i Norge er at alle gravide kvinner med økt risiko for å få et barn med en ... -
Arctic food biographies. An ethnographic study of food and health in everyday life of elderly Arctic women
(Doctoral thesis; Doktorgradsavhandling, 2020-12-04)<p>The aim of the ethnographic study described was to listen sensitively and give voice to elderly Arctic women’s personal food biographies and everyday experiences of living in small coastal towns and inland areas of Norway’s Circumpolar North, North West Russia and Greenland. These specified geographical contexts were selected because they have been the focus of the Arctic and Global Health research ... -
Kunnskapsoppsummering og klassifisering av tiltaket Psykologisk førstehjelp (2.utg.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-09)<i>Bakgrunn</i> - Denne artikkelen er en kunnskapsoppsummering av effektene for tiltaket Psykologisk førstehjelp. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Neumer & Eng, 2013), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier (Martinussen m. fl., 2019). Psykologisk førstehjelp (PF) er i hovedsak et selvhjelpsmateriell som retter ... -
Prevalence of symptoms, ever having received a diagnosis and treatment of depression and anxiety, and associations with health service use amongst the general population in two Russian cities
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-12)<i>Background</i> - Little is known about the burden of common mental disorders in Russia despite high levels of suicide and alcohol-related mortality. Here we investigated levels of symptoms, self-reports of ever having received a diagnosis and treatment of anxiety and depression in two Russian cities.<p> <p><i>Methods</i> - The study population was men and women aged 35–69 years old participating ... -
Ready for shared decision making: Pretesting a training module for health professionals on sharing decisions with their patients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-01)<i>Introduction</i> - While shared decision‐making (SDM) training programmes for health professionals have been developed in several countries, few have been evaluated. In Norway, a comprehensive curriculum, “klar for samvalg” (ready for SDM), for interprofessional health‐care teams was created using generic didactic methods and guidance to tailor training to various contexts. The programmes adapted ... -
Differences in sarcopenia prevalence between upper-body and lower-body based EWGSOP2 muscle strength criteria: the Tromsø study 2015–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-10)<p><i>Background - </i>The European Working Group on Sarcopenia in Older People (EWGSOP2) recommends grip strength and chair stand tests to be used as primary defining measures. It is unclear how either test affects prevalence estimates. <p><i>Methods - </i>This cross-sectional study involved 3498 community-dwelling participants (40–84 years) from the 7th Tromsø Study survey (2015–2016). We used ... -
Comparative effectiveness of microdecompression alone vs decompression plus instrumented fusion in lumbar degenerative spondylolisthesis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)<i>Importance</i> - Conflicting evidence and large practice variation are present in the surgical treatment of degenerative spondylolisthesis. More than 90% of surgical procedures in the United States include instrumented fusion compared with 50% or less in other countries.<p> <p><i>Objective</i> - To evaluate whether the effectiveness of microdecompression alone is noninferior to decompression ... -
How occupational health is assessed in mine workers in Murmansk Oblast
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-10)<i>Objectives</i>: We aimed to describe how work exposure and occupational health is assessed for mine workers in Murmansk Oblast, Russia. <p> <p><i>Study design</i>: A descriptive study based on current practice, laws and available literature. <p> <p><i>Methods</i>: The information and data were obtained from scientific publications, reports, regional and federal statistics, legal documents, ... -
The prevalence of hereditary neuromuscular disorders in Northern Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-13)<i>Aim</i> - To investigate the point prevalence of hereditary neuromuscular disorders on January 1, 2020 in Northern Norway.<p> <p><i>Methods</i> - From January 1, 1999, until January 1, 2020, we screened medical and genetic hospital records in Northern Norway for hereditary neuromuscular disorders.<p> <p><i>Results</i> - We identified 542 patients with a hereditary neuromuscular disorder ... -
Får jeg være med? En studie om muligheter og barrierer ledsagere til personer med utviklingshemming kan møte i sitt arbeid med å fremme kulturdeltakelse
(Master thesis; Mastergradsoppgave, 2020-06-25)Mange mennesker med utviklingshemming trenger støtte og tilrettelegging for å kunne delta i fritidsaktiviteter. De har krav på å kunne delta på lik linje som alle andre. Dette er nedfelt i politiske og offentlige dokumenter som NOU, konvensjoner, lover og føringer. Det viser seg derimot at selv om intensjonene i dokumentene er gode, føringene er klare, oppleves virkeligheten annerledes. I denne ...
