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norskDet helsevitenskapelige fakultet: Nye registreringer
Viser treff 1541-1560 av 10439
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Against All Odds? Sami Women’s Lower NEET Experience in An Arctic Context: Education and Work Participation among Multicultural Young People in Northern-Norway, the Norwegian Arctic Adolescent Health Study (NAAHS)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-25)The present paper explores Sami women’s lower NEET (Not engaged in Education, Employment or Training) experience in an ethnoreligious multicontext perspective. Data are derived from a cross-sectional cohort and registry follow-up study in Northern Norway, 2003–2012, and data from Statistics Norway are included for an up-to date data analysis (2021). This is a cross-sectional cohort and registry data ... -
A Longitudinal Study of Semantic Networks in Schizophrenia and other Psychotic Disorders Using the Word Association Task
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-24)The underpinnings of language deviations in psychotic symptoms (eg, formal thought disorder, delusions) remain unclear. We examined whether the semantic networks underlying word associations are useful predictors of clinical outcomes in psychosis. Fifty-one patients with schizophrenia and other psychotic disorders and 51 matched healthy controls generated words in a Cantonese continued word ... -
Interventions for osteoarthritis pain: A systematic review with network meta-analysis of existing Cochrane reviews
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)Objective: To conduct a network meta-analysis comparing all treatments for osteoarthritis (OA) pain in the Cochrane Library.<p> <p>Design: The Cochrane Library and Epistemonikos were searched for randomized controlled trials (RCTs) about treatments for hip and knee OA. We constructed 17 broad categories, comprising drug treatments, exercise, surgery, herbs, orthotics, passive treatments, ... -
Laser In Situ Keratomileusis (LASIK) Combined with Prophylactic Corneal Cross-Linking for Correction of Myopia: Regional Analysis of Corneal Morphology
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-09)Introduction: This study evaluated the outcomes of laser in situ keratomileusis (LASIK) combined with prophylactic corneal collagen cross-linking (CXL) in correcting myopia in cases with increased estimated risk of postoperative corneal ectasia, detected by regional analysis of corneal morphology.<p> <p>Methods: The retrospective study included 180 eyes of 99 patients. Group 1 (94 eyes of ... -
Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-24)Prostate cancer diagnosis and early stratification is an important aspect to avoid undertreatment of high-risk prostate cancer patients. Major Vault Protein (MVP) has been proposed as a prognostic biomarker in prostate cancer. PTEN and the immune checkpoint protein B7-H3 interact with MVP and are important in prostate cancer progression and therapy response. We evaluated the expression of MVP by ... -
Weight loss behaviour in obese patients
(Master thesis; Mastergradsoppgave, 2020-02-21)Background: Obesity is increasing worldwide, and especially amongst the younger population. Many obese people are trying to lose weight without long-term success. There are certain things that they struggle with, and it can vary from patient to patient, but knowing this they can better be helped by professionals. There are many questionnaires for this purpose, most of them with many questions. Aim ... -
Attitudes of Mental Health Service Users Toward Storage and Use of Electronic Health Records
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)Objective: Electronic health records (EHRs) are used for both clinical practice and research. Because mental health service users’ views are underrepresented in perspectives on EHR use, the authors examined service users’ awareness, attitudes, and opinions about EHR data storage and sharing.<p> <p>Methods: A mixed-methods, cross-sectional design was used to examine attitudes of 253 Norwegian ... -
Lifetime sunburn trajectories and associated risks of cutaneous melanoma and squamous cell carcinoma among a cohort of Norwegian women
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-05)Importance - To our knowledge, no study has prospectively investigated sunburn patterns over age periods from childhood to adulthood and their associations with skin cancer risk.<p> <p>Objective - To identify lifetime trajectories of sunburns and compare the association between these trajectories and subsequent risk of cutaneous melanoma and squamous cell carcinoma (cSCC).<p> <p>Design, ... -
Cooling to hypothermic circulatory arrest by immersion vs. cardiopulmonary bypass (CPB): Worse outcome after rewarming in immersion cooled pigs
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)Introduction: Cooling by cardiopulmonary bypass (CPB) to deep hypothermic cardiac arrest (HCA) for cardiac surgical interventions, followed by CPB-rewarming is performed on a routine basis with relatively low mortality. In contrast, victims of deep accidental hypothermia rewarmed with CPB generally have a much worse prognosis. Thus, we have developed an intact pig model to compare effects on ... -
Regional Variation in Utilisation of Healthcare Services - A study on hospital care in Norway
(Doctoral thesis; Doktorgradsavhandling, 2023-02-28)<p><i>Background:</i> In 1938, J. Alison Glover published a study on incidence of tonsillecto-mies in school children, demonstrating variation in treatment rates across school districts. Consequently, it rates raised questions as to what determines when to treat a patient. After Wennberg and Gittelsohns’ paper ‘Small Area Variations in Health Care Delivery’ was pub-lished in 1973, it became clear ... -
Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-20)Patients with acute venous thromboembolism (VTE) require anticoagulant therapy to prevent recurrent VTE and death, which exposes them to an inherent increased risk of bleeding. Identification of patients at high risk of bleeding, and mitigating this risk, is an essential component of the immediate and long-term therapeutic management of VTE. The bleeding risk can be estimated by either implicit ... -
Glioblastoma PET/MRI: kinetic investigation of [<sup>18</sup>F]rhPSMA-7.3, [<sup>18</sup>F]FET and [<sup>18</sup>F]fluciclovine in an orthotopic mouse model of cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-22)<b><p>Purpose</b> Glioblastoma multiforme (GBM) is the most common glioma and standard therapies can only slightly prolong the survival. Neo-vascularization is a potential target to image tumor microenvironment, as it defines its brain invasion. We investigate [<sup>18</sup>F]rhPSMA-7.3 with PET/MRI for quantitative imaging of neo-vascularization in GBM bearing mice and human tumor tissue and compare ... -
Can Difficult Lectures be Interesting AND Pleasant? Hedonic and Eudaimonic Feelings as a Function of Perceived Difficulty
(Master thesis; Mastergradsoppgave, 2022-12-01)What is it that makes challenge and complexity so appealing to humans? Research derived from positive psychology have tried to answer this question, and in the process found evidence suggesting that people experience different feelings as the perception of difficulty rises. In this study, using Gudrun Eckblad’s scheme theory as premise, we predicted that reported feelings of pleasure would be most ... -
Visual problems are associated with long-term fatigue after stroke
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-30)Objective: Post-stroke fatigue may be associated with functioning even in patients with mild stroke. In order to guide rehabilitation, the aim of this study was to investigate the independent contribution of 12 function-related domains to severe long-term fatigue.<p> <p>Design: Observational follow-up study. Subjects: A total of 144 stroke survivors (mean age 67.3, standard deviation (SD) 10.9 ... -
The effect of machine learning tools for evidence synthesis on resource use and time-to-completion: protocol for a retrospective pilot study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-17)Background Machine learning (ML) tools exist that can reduce or replace human activities in repetitive or complex tasks. Yet, ML is underutilized within evidence synthesis, despite the steadily growing rate of primary study publication and the need to periodically update reviews to reflect new evidence. Underutilization may be partially explained by a paucity of evidence on how ML tools can reduce ... -
Changing patterns in treatment, remission status, and categories in a long-term Nordic cohort study of juvenile idiopathic arthritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)Objective - To explore sustainability of achieved remission off medication and defined International League of Associations for Rheumatology (ILAR) categories in juvenile idiopathic arthritis (JIA) and describe the trajectory of disease course over time by comparing treatment, disease activity, and ILAR categories from baseline, 8 years, and 18 years after disease onset.<p> <p>Methods - A total ... -
Body mass index, waist circumference and pre-frailty/frailty: the Tromsø study 1994−2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-23)Objective This study investigated the association between obesity, assessed using body mass index (BMI) and waist circumference (WC), and pre-frailty/frailty among older adults over 21 years of follow-up. <p>Design Prospective cohort study. <p>Setting Population-based study among communitydwelling adults in Tromsø municipality, Norway. <p>Participants 2340women and 2169 men aged ≥45 years ... -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)Background Baricitinib has shown efcacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifcally on severe/critical COVID, including vaccinated participants.<p> <p>Methods Bari-SolidAct is a phase-3, multicentre, randomised, double-blind, placebo-controlled trial, enrolling participants from June 3, 2021 to March 7, 2022, stopped prematurely for external ... -
High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-21)Background: Experimental studies have shown that the complement activating enzyme MASP-2 (mannose-binding lectin associated serine protease 2) exhibits a thrombin-like activity and that inhibition of MASP-2 protects against thrombosis. In this study, we investigated whether plasma MASP-2 levels were associated with risk of future venous thromboembolism (VTE) and whether genetic variants linked to ... -
Feedback Effects on Mind Wandering: A Series of Online Experiments
(Mastergradsoppgave; Master thesis, 2022-05-01)Replicating in-lab experiments online can ensure scientific progress when physical contact is discouraged, like during the covid-19 pandemic. In this thesis, we replicated the results from Boayue et al. (2021) in-lab Mind Wandering (MW) experiment online. The task uses the Finger-Tapping Random Sequence Generation Task, a sustained attention task, equating MW with Task Unrelated Thoughts (TUTs). In ...
