Viser treff 2001-2020 av 10439

    • Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      <b><p>Background</b> About one in five strokes occur during sleep (wake-up stroke). People with wake-up strokes have previously been considered to be ineligiblefor thrombolytic treatment because the time of stroke onset is unknown. However, recent studies suggest benefit from recanalisationtherapies in selected patients. <b><p>Objectives</b> To assess the effects of intravenous thrombolysis ...
    • Reflexology for acute rhinosinusitis – Results from a blinded, early-phase comparative trial 

      Norheim, Arne Johan; Fønnebø, Vinjar; Lindeland, John Petter; Varpe, Terje; Bigset, Catarina; Stub, Trine; Kristoffersen, Agnete Egilsdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-06)
      Background - Reflexology is commonly used as an adjunct to conventional treatment by patients with respiratory tract infections. The effect of reflexology needs to be tested in a full-scale randomized controlled study. Small early-phase trials can give an indication on whether full-size clinical trials are warranted. The objective of this study is to determine whether the study design is feasible ...
    • Garbage codes in the Norwegian Cause of Death Registry 1996-2019 

      Ellingsen, Christian Lycke; Alfsen, Glenny Cecilie; Ebbing, Marta; Pedersen, Anne Gro; Sulo, Gerhard; Vollset, Stein Emil; Braut, Geir Sverre (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)
      Background: Reliable statistics on the underlying cause of death are essential for monitoring the health in a population. When there is insufcient information to identify the true underlying cause of death, the death will be classifed using less informative codes, garbage codes. If many deaths are assigned a garbage code, the information value of the cause-of-death statistics is reduced. The aim ...
    • Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up 

      Gjerstad, Ann Christin; Skrunes, Rannveig; Tøndel, Camilla; Åsberg, Anders; Leh, Sabine; Klingenberg, Claus Andreas; Døllner, Henrik; Hammarström, Clara Louise; Bjerre, Anna Kristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)
      Background There is scarce information on biopsy-verifed kidney disease in childhood and its progression to chronic kidney disease stage 5 (CKD 5). This study aims to review biopsy fndings in children, and to investigate risk of kidney replacement therapy (KRT).<p> <p>Methods We conducted a retrospective long-term follow-up study of children included in the Norwegian Kidney Biopsy Registry (NKBR) ...
    • Use of Complementary and Alternative Medicine in the context of cancer; prevalence, reasons for use, disclosure, information received, risks and benefits reported by people with cancer in Norway 

      Kristoffersen, Agnete Egilsdatter; Nilsen, Jorunn Valle; Nordberg, Johanna H.; Wider, Barbara; Mora, Dana Catalina; Nakandi, Kiwumulo; Bjelland, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-29)
      Background Research exploring the use of specific Complementary and Alternative Medicine (CAM) modalities by Norwegian cancer patients is sparse. The aims of this study were therefor to map the different CAM modalities cancer patients use and further investigate their rationale for use, communication about use, self-reported benefits and harms, and their sources of information about the different ...
    • Impact of total hip replacements on the incidence of hip fractures in Norway during 1999-2019. A NOREPOS study 

      Kjeldgaard, Helena Kames; Meyer, Haakon E.; O’Flaherty, Martin; Apalset, Ellen Margrete; Dahl, Cecilie; Emaus, Nina; Fenstad, Anne Marie; Furnes, Ove; Gjertsen, Jan-Erik; Hoff, Mari; Schei, Berit; Søgaard, Anne-Johanne; Tell, Grethe S.; Holvik, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-25)
      The knowledge about why hip fracture rates in Norway have declined is sparse. Concurrent with decreasing hip fracture rates, the rates of total hip replacements (THRs) have increased. We wanted to investigate if hip fracture rates continued to decline, and whether the increase in THRs had any influence on this decline, assuming that living with a hip prosthesis precludes fracture of the operated ...
    • Trauma team training in Norwegian hospitals: an observational study 

      Bredin, Ida Celine; Gaup, Hedi Marina Joks; Brattebø, Guttorm; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-05)
      Background: Traumatic injuries are a leading cause of deaths in Norway, especially among younger males. Traumarelated mortality can be reduced by structural measures, such as organization of a trauma system. Many hospitals in Norway treat few seriously injured patients, one of the reasons for development of the Norwegian trauma system. Since its implementation, there has been continuous improvement ...
    • Urinary orosomucoid is associated with diastolic dysfunction and carotid arteriopathy in the general population. Cross-sectional data from the Tromsø study 

      Andreassen, Runa Marie; Kronborg, Jens; Schirmer, Henrik; Mathiesen, Ellisiv B.; Melsom, Toralf; Eriksen, Bjørn Odvar; Jenssen, Trond Geir; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-02)
      Objectives. Urinary albumin excretion is a risk marker for cardiovascular disease (CVD). Studies suggest that urinary orosomucoid may be a more sensitive marker of general endothelial dysfunction than albuminuria. The aim of this population-based cross-sectional study was to examine the associations between urinary orosomucoid to creatinine ratio (UOCR), urinary albumin to creatinine ratio ...
    • Exploring patient safety in rural general practice - a mixed-methods approach 

      Harbitz, Martin Bruusgaard (Doctoral thesis; Doktorgradsavhandling, 2022-11-08)
      <p>Unsafe medical practices and incidents where safety hazards cause harm to patients occur daily in general practice. The costs to society, health care personnel and individual patients are substantial and deserve attention. “Hazards” can be regarded as local error-producing factors, latent failures, which create conditions for unsafe medical practice to take place. “Harm” occurs when these conditions ...
    • Fødselsstatistikken 2019 

      Macsali, Ferenc; Stangenes, Kristine Marie; Askeland, Olaug Margrete; Júlíusson, Pétur; Juliusson, Pétur Benedikt; Staff, Anne Cathrine (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Hoveddelen av dataene fra Medisinsk fødselsregister (MFR) for 2019 ble publisert i juni i år. Data om mors helse før og under svangerskapet samt data fra nyfødtavdelingene er publisert nå i desember og er tilgjengelig i vår statistikkbank. MFR har i år pga. den pågående pandemien også hatt en ekstrapublisering med et utvalg av variabler for 2020 data. Sjekk våre nettsider for mer informasjon om ...
    • Måleegenskaper ved den norske versjonen av Development and Well-being Assessment (DAWBA) 

      Brøndbo, Per Håkan; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-11-19)
      Beskrivelse. Development and Well-Being Assessment (DAWBA) ble utviklet på 1990-tallet i Storbritannia som et diagnostisk verktøy for å fange opp vanlige barne- og ungdomsdiagnoser (DSM-IV) (Goodman et al., 2000). Den norske oversettelsen ble gjort av Einar Heiervang, Kjerstin Søvik, Melanie Young, Anne Karin Ullebø og Ingrid Jangård Orre. Det finnes tre versjoner av DAWBA med spørsmål som rettes ...
    • Barnevernets undersøkelsesarbeid- oppsummering av hovedtrekkene i forskningslitteraturen. Delrapport 1 

      Vis, Svein Arild; Lauritzen, Camilla; Fossum, Sturla (Research report; Forskningsrapport, 2016-10-31)
      Denne rapporten er en oppsummering av hovedtrekkene i forskningslitteraturen om barnevernets undersøkelsesarbeid. Rapporten inneholder oversikt over (i) erfaringer med bruk av utredningsmaler internasjonalt, (ii) risikovurderinger, (iii) brukernes erfaringer med barnevernundersøkelser og (iv) forhold som har betydning for barnevernets beslutninger etter en undersøkelse.
    • Sex-specific factors associated with lifetime suicide attempt among patients with alcohol use disorders 

      Pandey, Susmita; Bolstad, Ingeborg; Lien, Lars; Walby, Fredrik A; Myhre, Martin Øverlien; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-18)
      Background<p> <p>Patients with alcohol use disorder (AUD) are at high risk for suicide attempts. Mental health problems along with AUD-related factors may contribute to this increased risk. Studies have shown sex differences in rates and correlates of suicide attempts. <p>Aims <p>The purpose of the study was to examine mental-health-related and AUD-related factors associated with suicide ...
    • p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria to Different Autophagy Pathways 

      Mostowy, Serge; Sancho-Shimizu, Vanessa; Hamon, Mélanie Anne; Simeone, Roxane; Brosch, Roland; Johansen, Terje; Cossart, Pascale (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-06-06)
      Autophagy is an important mechanism of innate immune defense. We have recently shown that autophagy components are recruited with septins, a new and increasingly characterized cytoskeleton component, to intracytosolic Shigella that have started to polymerize actin. On the other hand, intracytosolic Listeria avoids autophagy recognition by expressing ActA, a bacterial effector required for actin ...
    • The Regulation of Steroid Receptor Co-activator-3 Activity by p38MAPK-MK2 Signaling Pathway 

      Shrestha, Anup (Doctoral thesis; Doktorgradsavhandling, 2022-10-14)
      Steroid receptor co-activator-3 (SRC-3) is a co-activator that plays important roles in normal physiology and different diseases including cancer. Its activity is regulated by phosphorylation. Serine 857 (S857) is the most frequently reported phosphorylation site of SRC-3. In this work, we examined several kinases that could phosphorylate SRC-3 at S857 and explored the functional outcome incurred ...
    • Factors shaping initial decision-making to self-test amongst cohabiting couples in urban Blantyre, Malawi 

      Kumwenda, Moses; Munthali, Alister; Phiri, Mackwellings; Mwale, Daniel; Gutteberg, Tore Jarl; MacPherson, Eleanor; Theobald, Sally J.; Corbett, Liz; Desmond, Nicola (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-15)
      In sub-Saharan Africa, most new HIV infections occur in stable relationships, making couples testing an important intervention for HIV prevention. We explored factors shaping the decision-making of cohabiting couples who opted to self-test in Blantyre, Malawi. Thirty-four self-tested participants (17 couples) were interviewed. Motivators for HIV self-testing (HIVST) emerged at three main levels. ...
    • Seroprevalence of SARS-Cov-2 Antibodies in Adults, Arkhangelsk, Russia 

      Krieger, Ekaterina Anatoljevna; Kudryavtsev, Alexander V; Sharashova, Ekaterina; Postoev, Vitaly; Belova, Natalia; Shagrov, Leonid; Zvedina, Julia; Drapkina, Oxana; Kontsevaya, Anna; Shalnova, Svetlana; Brenn, Tormod; Shkolnikov, Vladimir M.; Eggo, Rosalind M.; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02)
      Population-based data on coronavirus disease in Russia and on the immunogenicity of the Sputnik V vaccine are sparse. In a survey of 1,080 residents of Arkhangelsk 40–75 years of age, 65% were seropositive for IgG. Fifteen percent of participants had been vaccinated; of those, 97% were seropositive.
    • Leder - Ramazzini 2/2022 

      Höper, Anje Christina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      I dette nummeret tar vi for oss prosjektarbeid i arbeids medisin som tema, med spesiell vekt på prosjekter I BHT. Men hva er egentlig prosjektarbeid?
    • Forskning i BHT 

      Skandfer, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Arbeidsmedisinsk forskning må være relevant og svare på aktuelle utfordringer i samfunnet. Slik kommer faget fremover. Gjennom forankring i praksis kan nye problemstillinger fanges opp, hypoteser genereres og bedre løsninger skapes. Det inngår i et større bilde der økt samhandling mellom akademia og praksis etterspørres av myndighetene og aktørene selv. Det gjelder forøvrig også mange andre ...
    • Nucleic acid peptide nanogels for the treatment of bacterial keratitis 

      Obuobi, Sybil Akua Okyerewa; Mayandi, Venkatesh; Nurul, Azlyn Mohd Nor; Lee, Benedict Jiasheng; Lakshminarayanan, Rajamani; Pui Lai, Rachel Ee (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-14)
      Cage-shaped nucleic acid nanocarriers are promising molecular scaffolds for the organization of polypeptides. However, there is an unmet need for facile loading strategies that truly emulate nature's host–guest systems to drive encapsulation of antimicrobial peptides (AMPs) without loss of biological activity. Herein, we develop DNA nanogels with rapid in situ loading of L12 peptide during the thermal ...