Viser treff 3061-3080 av 10466

    • Protein Appetite Drives Macronutrient-Related Differences in Ventral Tegmental Area Neural Activity 

      Chiacchierini, Giulia; Naneix, Fabien; Peters, Kate Z; Aspergis-Schoute, John; Snoeren, Eelke; McCutcheon, James Edgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Control of protein intake is essential for numerous biological processes as several amino acids cannot be synthesized de novo, however, its neurobiological substrates are still poorly understood. In the present study, we combined in vivo fiber photometry with nutrient-conditioned flavor in a rat model of protein appetite to record neuronal activity in the VTA, a central brain region for the control ...
    • External validation of a deep learning electrocardiogram algorithm to detect ventricular dysfunction 

      Attia, Itzhak Zachi; Tseng, Andrew S.; Benavente, Ernest Diez; Medina-Inojosa, Jose R.; Clark, Taane; Malyutina, Sofia; Kapa, Suraj; Schirmer, Henrik; Kudryavtsev, Alexander V; Noseworthy, Peter A.; Carter, Rickey E.; Ryabikov, Andrey; Perel, Pablo; Friedman, Paul A.; Leon, David A.; Lopez-Jimenez, Francisco (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-02)
      Objective - To validate a novel artificial-intelligence electrocardiogram algorithm (AI-ECG) to detect left ventricular systolic dysfunction (LVSD) in an external population.<p> <p>Background - LVSD, even when asymptomatic, confers increased morbidity and mortality. We recently derived AI-ECG to detect LVSD using ECGs based on a large sample of patients treated at the Mayo Clinic.<p> <p>Methods ...
    • Stratification of Culture-Proven Early-Onset Sepsis Cases by the Neonatal Early-Onset Sepsis Calculator: An Individual Patient Data Meta-Analysis 

      Achten, Niek B.; Plötz, Frans B.; Klingenberg, Claus; Stocker, Martin; Bokelaar, Robin; Bijlsma, Merijn; Giannoni, Eric; van Rossum, Annemarie M.C.; Benitz, William E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-03)
      Objectives - To provide a comprehensive assessment of case stratification by the Neonatal Early-Onset Sepsis (EOS) Calculator, a novel tool for reducing unnecessary antibiotic treatment.<p> <p>Study design - A systematic review with individual patient data meta-analysis was conducted, extending PROSPERO record CRD42018116188. Cochrane, PubMed/MEDLINE, EMBASE, Web of Science, Google Scholar, and ...
    • Effects of age and gender on the relationship between alcohol use disorder and somatic diseases: a national register study in Norway 

      Abebe, Dawit Shawel; Lien, Lars; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-10)
      Objective - This study aimed to examine how age and gender moderate the associations between alcohol use disorders (AUD) and several somatic diseases. <p> <p>Design and setting - We performed a retrospective, register-based cohort study with 6-year follow-up of patients with AUD and the general population. Data were acquired from the Norwegian Patient Registry. Cox regressions were used to estimate ...
    • A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018 

      Tryland, Morten; Sanchez Romano, Javier; Nymo, Ingebjørg Helena; Breines, Eva Marie; Murguzur, Francisco Javier Ancin; Kjenstad, Ole Christian; Li, Hong; Cunha, Cristina W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-12)
      Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e., Cervid herpesvirus 2; CvHV2) has been identified as the transmissible component of infectious keratoconjunctivitis (IKC). Limited knowledge exists ...
    • “Mapping suicide prevention initiatives targeting Indigenous Sámi in Nordic countries” 

      Stoor, Jon Petter A.; Eriksen, Heidi A.; Silviken, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-07)
      Background - Suicide is a major public health issue among Indigenous Sámi in Nordic countries, and efforts to prevent suicide in the Sámi context are increasing. However, there is no literature on suicide prevention initiatives among Sámi. The aim of the study was to map suicide prevention initiatives targeting Sámi in Norway, Sweden, and Finland during 2005–2019.<p> <p>Method - Initiatives were ...
    • Effectiveness of Natalizumab in Achieving No Evidence of Disease Activity (NEDA-3)—Data From a Local Norwegian Cohort 

      Jaklin, Andreas K.; Benjaminsen, Espen; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-20)
      Objective: We aimed to determine the effectiveness of natalizumab (NTZ) by assessing overall No Evidence of Disease Activity 3 (NEDA-3) in a local Norwegian cohort. <p> <p>Background: NTZ is an immunomodulating drug used in the treatment of multiple sclerosis (MS). It has typically been used as a second-line treatment, but certain patients with high disease activity have started directly with ...
    • Assessing a Sensory-Motor-Cognition Triad in Amnestic Mild Cognitive Impairment With Dichotic Listening While Walking: A Dual-Task Paradigm 

      Gorecka, Marta Maria; Vasylenko, Olena; Waterloo, Knut; Rodriguez-Aranda, Claudia (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-12)
      A contemporary topic in aging research relates to the significance of cognitive changes proper to mild cognitive impairment (MCI) to higher risk of falls and gait deteriorations. The present study addresses this question in the amnestic type of MCI (aMCI) by examining a triad of interrelated comorbidities occurring in the MCI condition: attentional impairments, hearing loss and gait disturbances. ...
    • Maintaining intravenous volume mitigates hypothermia-induced myocardial dysfunction and accumulation of intracellular Ca2+ 

      Nilsen, Jan Harald; Schanche, Torstein; Kondratiev, Timofei V.; Hevrøy, Olav; Tveita, Torkjel; Sieck, Gary C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      Previous research exploring pathophysiological mechanisms underlying circulatory collapse after rewarming victims of severe accidental hypothermia has documented post-hypothermic cardiac dysfunction and hypothermia-induced elevation of intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]<sub>i</sub>) in myocardial cells. The aim of the present study was to examine if maintaining euvolaemia ...
    • Cut-off values of serum potassium and core temperature at hospital admission for extracorporeal rewarming of avalanche victims in cardiac arrest: A retrospective multi-centre study 

      Brugger, Hermann; Bouzat, Pierre; Pasquier, Mathieu; Mair, Peter; Fieler, Julia; Darocha, Tomasz; Blancher, Marc; de Riedmatten, Matthieu; Falk, Markus; Paal, Peter; Strapazzon, Giarcome; Zafren, Ken; Maeder, Monika Brodmann (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06)
      Aim: Evidence of existing guidelines for the on-site triage of avalanche victims is limited and adherence suboptimal. This study attempted to find reliable cut-off values for the identification of hypothermic avalanche victims with reversible out-of-hospital cardiac arrest (OHCA) at hospital admission. This may enable hospitals to allocate extracorporeal life support (ECLS) resources more appropriately ...
    • “Walking Together Towards Freedom.” Patients’ Lived Experiences of Participation in Outpatient Forensic Care 

      Anni, Waxell; Wiklund Gustin, Lena (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-11)
      There is a general agreement regarding the significance of patient participation in care. In forensic psychiatric care, however, this appears to be troublesome because of the paradoxical nature of having responsibility; to give person-centered, recovery-oriented psychiatric care and to protect society from potentially dangerous individuals. The aim of this study was to describe patients’ lived ...
    • Undiagnosed diabetes based on HbA 1c by socioeconomic status and healthcare consumption in the Tromsø Study 1994-2016 

      Lopez-Doriga Ruiz, Paz; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Njølstad, Inger; Grimnes, Guri; Stene, Lars Christian Mørch; Gulseth, Hanne Løvdal (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-15)
      Introduction - We aimed to investigate whether the proportion of undiagnosed diabetes varies by socioeconomic status and healthcare consumption, in a Norwegian population screened with glycated hemoglobin (HbA1c).<p> <p>Research - design and methods In this cohort study, we studied age-standardized diabetes prevalence using data from men and women aged 40–89 years participating in four surveys ...
    • Physiopunk Vol 1 

      Maric (PhD), Filip; Nikolaisen, Liv Johanne; Bårdsen, Åse (Journal article; Tidsskriftartikkel, 2021)
      Physiopunk emerged out of an introductory public health module for first-year students in the Bachelor program in physiotherapy at UiT The Arctic University of Norway. Throughout the module, students gradually expanded their view of physiotherapy, from its past and present individual and physical health focus toward the integration of social and ecological issues as fundamental determinants of ...
    • Physiopunk Vol. 1 Speculative fiction for future physiotherapies 

      Maric (PhD), Filip; Nikolaisen, Liv Johanne; Bårdsen, Åse (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      In light of today’s deeply connected social and environmental crises, environmental and sustainability education is increasingly being integrated into public health and healthcare professional education around the world (Barna, Maric, Simons, Kumar & Blankestijn, 2020). The Norwegian ‘regulations on national guidelines for physiotherapist education’ clearly support the integration of these topics ...
    • Physiopunk Vol 1 Spekulativ fiksjon for fremtidige fysioterapier 

      Maric (PhD), Filip; Nikolaisen, Liv Johanne; Bårdsen, Åse (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      Dagens sosiale og miljømessige kriser er dypt forbundet med hverandre. Miljø- og bærekraftsutdanning blir derfor stadig mer integrert i internasjonale folkehelse- og helsepersonellutdanninger (Barna, Maric, Simons, Kumar & Blankestijn, 2020). Den norske «Forskrift om nasjonal retningslinje for fysioterapeututdanning» støtter integrering av disse temaene og sier at fysioterapeuter «skal […] bidra på ...
    • Influence of Internalised Homonegativity on Sexual Risk Behaviour of Men Who Have Sex with Men in Spain 

      Sönmez, İbrahim; Folch, Cinta; Lorente, Nicolas; Berg, Rigmor; Thurlby, Natalie; Schmidt, Axel J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-27)
      In a sample of men who have sex with men (MSM) (N = 3436) in Spain who bear intrinsic HIV risk, we investigated how internalised homonegativity (IH) is associated with the number of non-steady male partners with condomless intercourse (as a proxy of sexual risk behaviour). Using structural equation modelling (SEM), we examined the relationship between IH and sexual risk behaviour, and mediating ...
    • Restorative treatment decisions for carious lesions: Do Russian dentists and dental students apply minimal intervention dentistry? 

      Drachev, Sergei Nikolaevich; Galieva, Alexandra S.; Yushmanova, TN; Polivanaya, Elena A.; Stangvaltaite-Mouhat, Lina; Al-Mahdi, Rania; Leinonen, Jukka; Stein, Linda Maria; Davidova, Nadezhda G.; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-15)
      Background - The concept of minimal intervention dentistry (MID) includes both delayed restorative treatment and conservative caries removal, and is now recognised as an evidence-based approach for dental caries management. In order to determine if dental professionals in Russia are incorporating this concept into their clinical practice, we investigated the restorative treatment decisions of Russian ...
    • Changed definition of disease and broader screening criteria had little impact on prevalence of gestational diabetes mellitus 

      Grønvall, Lina; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-26)
      Introduction - There are major controversies in screening for gestational diabetes mellitus (GDM). The present study evaluates the impact of the 2017 revised guidelines for GDM screening and a changed definition of GDM in Norway.<p> <p>Material and methods - We used a case-series design and included women with no pre-pregnancy diabetes mellitus, who gave birth after gestational week 29 to a ...
    • Nanocarriers for tailored skin delivery: More than just the carriers? 

      Ternullo, Selenia (Doctoral thesis; Doktorgradsavhandling, 2018-11-23)
      Skin diseases are among the top 5 most leading diseases causing non-fatal health burden worldwide and strategies to assure more effective treatments are urgently needed. Dermal therapy is very attractive due to the direct administration of the drug at the diseased skin site thus minimizing systemic side effects associated with the oral and parenteral routes. However, the great variety within the ...
    • The Effects of Virtual Reality on Procedural Pain and Anxiety in Pediatrics 

      Nordgård, Rikke (Master thesis; Mastergradsoppgave, 2020-12-15)
      Distraction and procedural preparation techniques are frequently used to manage pain and anxiety in children undergoing medical procedures. An increasing number of studies have indicated that Virtual Reality (VR) can be used to deliver these interventions, but treatment effects vary greatly. The present study is a systematic review and meta-analysis of studies that have used VR to reduce procedural ...