Viser treff 3381-3400 av 10469

    • Association of High-Density Lipoprotein Cholesterol With GFR Decline in a General Nondiabetic Population 

      Melsom, Toralf; Norvik, Jon Viljar; Enoksen, Inger Therese; Stefansson, Vidar Tor Nyborg; Rismo, Renathe; Jenssen, Trond; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
      <i>Introduction</i> - Although lower high-density lipoprotein cholesterol (HDL-C) levels are considered a risk factor for cardiovascular disease (CVD), experimental evidence suggest that aging, inflammation, and oxidative stress may remodel HDL-C, leading to dysfunctional HDL-C. Population studies on HDL-C and loss of the glomerular filtration rate (GFR) reported inconsistent results, but they used ...
    • Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort 

      Wirsing, Anna Maria; Bjerkli, Inger-Heidi; Steigen, Sonja Eriksson; Rikardsen, Oddveig G; Norvoll Magnussen, Synnøve; Hegge, Beate; Seppola, Marit; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)
      The Pathology Atlas is an open-access database that reports the prognostic value of protein-coding transcripts in 17 cancers, including head and neck cancer. However, cancers of the various head and neck anatomical sites are specific biological entities. Thus, the aim of the present study was to validate promising prognostic markers for head and neck cancer reported in the Pathology Atlas in oral ...
    • Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi 

      Phiri, Abel F.N.D.; Abia, Akebe Luther King; Amoako, Daniel Gyamfi; Mkakosya, Rajab; Sundsfjord, Arnfinn; Essack, Sabiha; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-28)
      Although numerous studies have investigated diarrhoea aetiology in many sub-Saharan African countries, recent data on <i>Shigella</i> species’ involvement in community-acquired acute diarrhoea (CA-AD) in Malawi are scarce. This study investigated the incidence, antibiotic susceptibility profile, genotypic characteristics, and clonal relationships of <i>Shigella flexneri</i> among 243 patients ...
    • Frafall i organisert fotball gjennom en sesong preget av COVID-19 i samfunnet – Et trenerperspektiv 

      Blomstrand, Tommy Hauge (Master thesis; Mastergradsoppgave, 2021-05-26)
      Sammendrag Introduksjon: I begynnelsen av 2020 ble samfunnet i Norge rammet av COVID-19. Dette medførte begrensninger for idretten i landet, som samfunnet generelt. Dette har medført begrenset mulighet for organisert fotball. Norges fotballforbund har rapportert om frafall på 8% i barne- og ungdomsfotballen og det fryktes større frafall i seniorfotballen. Videre tar den teoretiske rammen i denne ...
    • Responses after spinal interventions in a clinical pain practice - A pragmatic observational study 

      Måwe, Leif; Thorén, Lena Måwe; Kvarstein, Gunnvald (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-24)
      Introduction - There is limited evidence for effect of interventional treatment, and pragmatic studies are needed to assess these interventions within a clinical setting. The aim of this study was to describe patients referred to an interventional pain clinic and investigate responses after spinal intervention in general and for radiofrequency ablation (RFA) and transforaminal epidural corticosteroid ...
    • Thromboembolic Events During Treatment with Cisplatin-based Chemotherapy in Metastatic Testicular Germ-cell Cancer 2000–2014: A Population-based Cohort Study 

      Haugnes, Hege S.; Negaard, Helene F.; Negaard, Helene Francisca Stigter; Jensvoll, Hilde; Wilsgaard, Tom; Tandstad, Torgrim; Solberg, Arne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-15)
      <i>Background</i> - Cisplatin-based chemotherapy (CBCT) in testicular cancer (TC) is associated with elevated venous thromboembolism (VTE) risk, but trials evaluating the safety and efficacy of thromboprophylaxis are lacking.<br><br> <i>Objective</i> - To evaluate the arterial thromboembolism (ATE) and VTE incidence and risk factors during first-line CBCT for metastatic TC, and the effect of ...
    • Intake of Vegetables, Fruits and Berries and Compliance to “Five-a-Day” in a General Norwegian Population—The Tromsø Study 2015–2016 

      Nilsen, Linn; Hopstock, Laila Arnesdatter; Grimsgaard, Sameline; Carlsen, Monica Hauger; Lundblad, Marie Wasmuth (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-18)
      Vegetables, fruits and berries are associated with reduced disease risk, and recommended intake is “five-a-day”. We studied the intake of vegetables, fruits and berries and compliance with “five-a-day” in 11,425 adults (40–96 years) who completed a food frequency questionnaire in the seventh wave of the Tromsø Study (2015–2016). Intake and proportion above/below recommended intake (250 g/day of ...
    • Chronic obstructive pulmonary disease does not impair responses to resistance training 

      Mølmen, Knut Sindre; Hammarström, Jens Konrad Daniel; Falch, Gunnar Slettaløkken; Grundtvig, Morten; Koll, Lise; Hanestadhaugen, Marita; Khan, Yusuf; Ahmad, Rafi; Malerbakken, Bente; Rødølen, Tore Jørgen; Lien, Roger; Rønnestad, Bent; Raastad, Truls; Ellefsen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-06)
      <i>Background</i> - Subjects with chronic obstructive pulmonary disease (COPD) are prone to accelerated decay of muscle strength and mass with advancing age. This is believed to be driven by disease-inherent systemic pathophysiologies, which are also assumed to drive muscle cells into a state of anabolic resistance, leading to impaired abilities to adapt to resistance exercise training. Currently, ...
    • The global dissemination of hospital clones of Enterococcus faecium 

      van Hal, Sebastiaan J.; Willems, Rob J.L.; Gouliouris, Theodore; Ballard, Susan A.; Coque, Teresa M.; Hammerum, Anette M.; Hegstad, Kristin; Westh, Henrik; Howden, Benjamin P.; Malhotra-Kumar, Surbhi; Werner, Guido; Yanagihara, Katsunori; Earl, Ashlee M.; Raven, Katherine E.; Corander, Jukka; Bowden, Rory (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      <i>Background</i> - The hospital-adapted A1 group of <i>Enterococcus faecium</i> remains an organism of significant concern in the context of drug-resistant hospital-associated infections. How this pathogen evolves and disseminates remains poorly understood.<br><br> <i>Methods</i> - A large, globally representative collection of short-read genomic data from the hospital-associated A1 group of ...
    • Validating Biobehavioral Technologies for Use in Clinical Psychiatry 

      Cohen, Alex S.; Cox, Christopher R.; Tucker, Raymond P.; Mitchell, Kyle R.; Schwartz, Elana K.; Le, Thanh P.; Foltz, Peter W.; Holmlund, Terje Bektesevic; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-11)
      The last decade has witnessed the development of sophisticated biobehavioral and genetic, ambulatory, and other measures that promise unprecedented insight into psychiatric disorders. As yet, clinical sciences have struggled with implementing these objective measures and they have yet to move beyond “proof of concept.” In part, this struggle reflects a traditional, and conceptually flawed, application ...
    • Early-Onset Sepsis in Neonates - A Population-Based Study in South-West Norway From 1996 to 2018 

      Vatne, Anlaug; Klingenberg, Claus; Rettedal, Siren; Øymar, Knut Asbjørn Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i>: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy strategies.<br><br> <i>Objectives</i>: To describe the incidence of culture-confirmed EOS, causative pathogens, antibiotic susceptibility patterns and antibiotic therapy ...
    • What factors explain the much higher diabetes prevalence in Russia compared with Norway? Major sex differences in the contribution of adiposity 

      Iakunchykova, Olena; Averina, Maria; Wilsgaard, Tom; Malyutina, Sofia; Kudryavtsev, Alexander V; Cook, Sarah; Wild, Sarah; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-04)
      <i>Introduction</i> - Compared with many other countries Russia has a high prevalence of diabetes in men and women. However, contrary to what is found in most other populations, the risk is greater among women than men. The reasons for this are unclear.<br><br> <i>Research design and methods</i> - Prevalence and risk factors for diabetes at ages 40–69 years were compared in two population-based ...
    • Global blood gene expression profiles following a breast cancer diagnosis - Clinical follow-up in the NOWAC post-genome cohort 

      Olsen, Karina Standahl; Holden, Marit; Thalabard, Jean-Christophe; Busund, Lill-Tove Rasmussen; Lund, Eiliv; Holden, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)
      <i>Objective</i> - This explorative study aimed to assess if there are any time-dependent blood gene expression changes during the first one to eight years after breast cancer diagnosis, which can be linked to the clinical outcome of the disease.<br><br> <i>Material and methods</i> - A random distribution of follow-up time from breast cancer diagnosis till blood sampling was obtained by a nested, ...
    • Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity 

      Raffelsberger, Niclas Peter; Hetland, Marit Andrea Klokkhammer; Svendsen, Kristian; Småbrekke, Lars; Löhr, Iren Høyland; Andreassen, Lotte; Brisse, Sylvain; Holt, Kathryn E.; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Gravningen, Kirsten Midttun (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-28)
      Antibiotic resistant <i>Klebsiella pneumoniae</i> is a leading public health threat and gastrointestinal carriage is an established risk factor for subsequent infections during hospitalization. Our study contributes new knowledge of risk factors for gastrointestinal carriage and the genomic population structure of <i>K. pneumoniae</i> colonizing humans in a representative sample of a general population ...
    • Dental anxiety in adolescents and adults. Epidemiological studies based on the Tromsø Study 7 and Fit Futures 1 & 2 

      Nermo, Hege (Doctoral thesis; Doktorgradsavhandling, 2021-10-01)
      <p><i>Background:</i> High dental anxiety can hinder individuals from seeking necessary dental treatment and thereby an obstacle in ensuring equal access to health care in the population. The overall aim of this thesis was to advance the understanding of dental anxiety in adolescents and adults, with a focus on the relevance of mental health symptoms, oral health and potentially traumatic events. ...
    • Gode barnevernsinstitusjoner: en systematisk kartleggingsoversikt 

      Johansen, Trine Bjerke; Jardim, Patricia Sofia Jacobsen; Blaasvær, Nora; Ames, Heather Melanie R; Munthe-Kaas, Heather Eileen Menzies; Tingulstad, Alexander; Berg, Rigmor (Research report; Forskningsrapport, 2020-06-10)
      Vi undersøkte hva forskning fra 2010-2019 sier om tiltak, metoder og strategier som skal legge til rette for god omsorg for barn og unge i barnevernsinstitusjoner.
    • Emotional Infant Face Processing in Women With Major Depression and Expecting Parents With Depressive Symptoms 

      Bohne, Agnes; Nordahl, Dag; Lindahl, Åsne; Ulvenes, Pål Gunnar; Wang, Catharina Elisabeth Arfwedson; Pfuhl, Gerit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-02)
      Processing of emotional facial expressions is of great importance in interpersonal relationships. Aberrant engagement with facial expressions, particularly an engagement with sad faces, loss of engagement with happy faces, and enhanced memory of sadness has been found in depression. Since most studies used adult faces, we here examined if such biases also occur in processing of infant faces in those ...
    • Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty 

      Ibrahim, Mustafa; Hedlundh, Urban; Sernert, Ninni; Meknas, Khaled; Haag, Lars; Movin, Tomas; Papadogiannakis, Nikos; Kartus, Jüri-Tomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-26)
      <i>Background</i> - Despite gluteus medius (GMED) tendinosis being relatively common, its presence in association with hip osteoarthritis (OA) or total hip arthroplasty (THA) is not well studied. It was hypothesized that more tendon degeneration would be found in patients with OA of the hip and in those that had undergone THA than that in a control group.<br><br> <i>Methods</i> - One hundred ...
    • Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial 

      Kuwelker, Kanika; Langeland, Nina; Löhr, Iren Høyland; Gidion, Joshua; Manyahi, Joel; Moyo, Sabrina John; Blomberg, Bjørn; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)
      <i>Background</i> - Extended-spectrum beta-lactamase-producing <i>Enterobacteriaceae</i> (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new treatment. Studies have shown high mortality in Tanzanian children with ESBL-E infections. Gut colonization of ESBL-E, which is a potential risk factor of ESBL-E ...
    • Behandlingsvalg hos lungekreftpasienter med NSCLC i tidlig stadium med fokus på komorbiditet og funksjonsstatus - En kvalitetsikringsstudie ved Universitetssykehuset Nord-Norge 

      Dalhaug, Marte; Leinan, Mariell (Master thesis; Mastergradsoppgave, 2020-09-01)
      <p>Bakgrunn: Lungekreft er den kreftsykdommen som tar flest liv, likevel kan pasienter med tidlig stadium ikke-småcellet lungekreft (NSCLC) ofte tilbys kurativ behandling og overlevelsen er betydelig bedret fra tidligere. Formålet med denne studien var å undersøke om pasienter har fått behandling i tråd med retningslinjene i Handlingsprogrammet for lungekreft, med særlig vekt på andel kurativ ...