Even though planning is generally helpful in goal pursuit, people do not always choose to plan. The inclination to plan might depend on whether we focus on what we seek to approach or what we seek to avoid. In two pre-registered experiments, we tested the relative effect of approach versus avoidance motivation on willingness to plan (total <i>N</i>=1349). With outcome framing as the experimental ...

The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five N-terminal epidermal growth factor-like domains, a linker region harbouring two integrin-binding motifs (RGD and LFEIFEIER), and a C-terminal MAM domain. In this review, we look into ...

Objective - Standardised cancer patient pathways (CPP) are implemented within cancer care with an aim to ensure standardised waiting times for diagnosis and treatment. This article investigates how patients in Norway experience waiting times within a CPP.<p> <p>Methods - Qualitative semi-structured interviews with 19 patients who had been through CPP for breast cancer, prostate cancer or malignant ...

Disruptions in attention, salience and increased distractibility are implicated in multiple psychiatric conditions. The ventral tegmental area (VTA) is a potential site for converging information about external stimuli and internal states to be integrated and guide adaptive behaviours. Given the dual role of dopamine signals in both driving ongoing behaviours (e.g., feeding) and monitoring salient ...

Beskrivelse. Kartlegging av traumeerfaringer og symptomer (KATES Barn) er et screeninginstrument for barn i alderen 7–17 år som gir foreløpig informasjon om mulig posttraumatisk stress. KATES Barn kommer i to deler; del 1 fanger opp traumatiske hendelser, og del 2 måler symptomer på posttraumatisk stress. Del 2 er delt opp i fire symptomkategorier tilpasset de diagnostiske endringene av traumediagnosen ...

<i>Background</i>: The Tn<i>916</i>-Tn<i>1545</i> family of Integrative Conjugative Elements (ICE) are mobile genetic elements (MGEs) that play a role in the spread of antibiotic resistance genes. The Tn<i>916</i> harbors the tetracycline resistance gene <i>tet</i>(M) and it has been reported in various bacterial species. The increase in the levels of tetracycline resistance among oral streptococci ...

Bakgrunn: Myndighetene har forventninger om at bidrag fra pårørende og frivillige i omsorg for hjemmeboende eldre skal opprettholdes på dagens nivå eller økes i fremtiden. I artikkelen undersøker vi potensialet for uformell omsorg med utgangspunkt i den demografiske utviklingen frem mot 2040. Metode: Med utgangspunkt i folketall fra 2018 og Statistisk sentralbyrås befolkningsframskrivinger 2018–2040 ...

The persistence of plasmids in bacterial populations represents a puzzling evolutionary problem with serious clinical implications due to their role in the ongoing antibiotic resistance crisis. Recently, major advancements have been made toward resolving this “plasmid paradox” but mainly in a nonclinical context. Here, we propose an additional explanation for the maintenance of multidrug‐resistance ...

Background: To study fatigue in young adults with juvenile idiopathic arthritis (JIA) 18 years after disease onset, and to compare with controls. Methods: Consecutive children with onset of JIA between 1997 and 2000, from geographically defined areas of Norway, Sweden, Denmark and Finland were followed for 18 years in a close to population-based prospective cohort study. Clinical features, ...