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Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-01)Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, characterized by inadequate antibody responses and recurrent bacterial infections. Paradoxically, a majority of CVID patients have non-infectious inflammatory and autoimmune complications, associated with systemic immune activation. Our aim was to explore if HDL, known to have anti-inflammatory properties, ... -
Adult mental health outpatients who have minor children: Prevalence of parents, referrals of their children, and patient characteristics
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-02)<i>Background</i>: A strong connection exists between parental mental illness and lifetime mental health risk for their children. Thus, it is important to determine, when parents attend for treatment for their illness, the prevalence and characteristics of parents with a mental illness and identify referral actions for their children. Previous studies indicate that 12–45% of adult mental health ... -
Estimated 8-year cumulative incidence of diabetes mellitus among Sami and non-Sami inhabitants of Northern Norway - The SAMINOR Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-24)<i>Background</i>: The aim of the study was to estimate and compare the 8-year cumulative incidence of diabetes mellitus (DM) among Sami and non-Sami inhabitants of rural districts in Northern Norway.<p> <p><i>Methods</i>: Longitudinal study based on linkage of two cross-sectional surveys, the SAMINOR 1 Survey (2003–2004) and the SAMINOR 2 Clinical Survey (2012–2014). Ten municipalities in rural ... -
Musculoskeletal symptoms among workers in the commercial fishing fleet of Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)<i>Background</i>: Fishers exposed to unfavourable environmental conditions may suffer negative health ef- fects. This study aimed to identify musculoskeletal symptoms in professional fishers in Norway using data from several sources; register data, telephone survey and questionnaire.<p> <p><i>Materials and methods</i>: Professional fishers (n = 25,971) registered in the period 2008-2013 were ... -
Effects of Linear Versus Changes of Direction Repeated Sprints on Intermittent High Intensity Running Performance in High-level Junior Football Players over an Entire Season: A Randomized Trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-06)<i>Abstract</i>: Background: Changes of direction (COD) repeated sprints (RSs) might have greater relevance to football than linear RSs. We aimed to compare the effects of linear and COD RSs on intermittent high intensity running (HIR) over an entire season. <p> <p><i>Methods</i>: In total, 19 high-level male football players (16–19 years) randomly performed linear RSs or COD RSs twice a week ... -
Creatine kinase is associated with reduced inflammation in a general population: The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-29)<p><i>Background</i>: Creatine kinase (CK) has been associated with reduced inflammation in obesity while inflammation is associated with obesity-related cardiovascular diseases. We investigated the relationship between CK and high sensitive C-reactive protein (hs-CRP) in a general population.</p> <p><i>Methods</i>: CK and hs-CRP were measured in the population-based Tromsø study that included ... -
Knowledge, attitude and practice on diet and physical activity among mothers with young children in the Jhaukhel-Duwakot Health Demographic Surveillance Site, Nepal
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-09)The prevalence of cardiovascular diseases is increasing in low and middle-income countries; Nepal’s population shows a high prevalence of behavioral risk factors. Our cross-sectional study in the Jhaukhel-Duwakot Health Demographic Surveillance Site (JD-HDSS), located near the capital Kathmandu, explored knowledge, attitude, and practice (KAP) of mothers with young children regarding diet and physical ... -
From wholes to fragments to wholes—what gets lost in translation?
(Journal article; Tidsskriftartikkel, 2018-05-31)The highly demanding and, in a certain sense, unique, working conditions of general practitioners (GPs) are characterized by two phenomena: First, they involve an increasing familiarity with individual patients over time, which promotes a deepening of insight. Second, they enable the GP to encounter all kinds of health problems, which in turn facilitates pattern recognition, at both individual and ... -
Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-28)<p><i>Objective</i>: To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes.</p> <p><i>Methods</i>: Consecutive cases of JIA with disease onset 1997‐2000 from defined geographical areas of Norway, Sweden, Finland and Denmark were prospectively enrolled in this population‐based cohort study. Self‐reported, disease‐related ... -
Lower attendance rates in BreastScreen Norway among immigrants across all levels of socio-demographic factors: a population-based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-03)<i>Background:</i> Several studies have shown that immigrants attend mammographic screening less frequently than non-immigrants. Studies have also shown that attendance is influenced by socio-demographic factors. We aimed to describe the relationship between socio-demographic factors and first attendance among immigrant and non-immigrant women invited to BreastScreen Norway.<p> <p><i>Methods:</i> ... -
Safe Surgery Checklist, Patient Safety, teamwork, and Responsibility - Coequal Demands? A Focus Group Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-28)The use of World Health Organization’s (WHO’s) Safe Surgery checklist is an established practice worldwide and contributes toward ensuring patient safety and collaborative teamwork. The aim of this study was to elucidate operating room nurses’ and operating room nursing students’ experiences and opinions about execution of and compliance with checklists. We chose a qualitative design with semistructured ... -
Promoting Professional Development in Medical education: perspectives from the Norwegian Medical School in Tromsoe
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-16)In international research on medical education the concepts of professionalism and professional development have been increasingly focused. The article problematizes and discusses these concepts in relation to the Aristotelian concepts of episteme, techne and phronesis. Phronesis as a form of knowledge is of fundamental importance regarding professionalism and professional development, and can be ... -
Effect of a Fracture Liaison Service on the Rate of Subsequent Fracture Among Patients With a Fragility Fracture in the Norwegian Capture the Fracture Initiative (NoFRACT)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-07)<p><i>Importance</i>: Fragility fracture is a major health issue because of the accompanying morbidity, mortality, and financial cost. Despite the high cost to society and personal cost to affected individuals, secondary fracture prevention is suboptimal in Norway, mainly because most patients with osteoporotic fractures do not receive treatment with antiosteoporotic drugs after fracture ... -
“What matters to you?” A longitudinal qualitative study of Norwegian patients’ perspectives on their pathways with colorectal cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-12)<p><i>Purpose</i>: Person-centred care (PCC) is a well-acknowledged goal throughout the western world both within the health care services sector and for the patients themselves. To be able to create a future health care system that includes improved PCC, we need more in-depth knowledge of what matters to patients, how “what matters” might change over time, and tentative descriptions of commonalities ... -
Omsorg for den samfunnsnyttige kroppen
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)Den franske filosofen Michel Foucault argumenterte for at ein har styrt moderne samfunn ved hjelp av samankoplingar mellom kroppslege praksisar og vitskap. Denne styringsforma kalla han disiplinering. I denne artikkelen argumenterer me for at den politiske argumentasjonen i siste halvdel av 1800-talet og starten av 1900-talet, om å legge om frå folkeleg til borgarleg reinsemd, kan ha vore ein lekk ... -
Pasientrapportert tilfredshet og livskvalitet etter ulike kirurgiske inngrep ved brystkreft
(Research report; Forskningsrapport, 2018-09-20)Bakgrunn: Primær behandling ved brystkreft er kirurgi. Kirurgiske alternativer ved brystkreft er mastektomi, lumpektomi, mastektomi med primær brystrekonstruksjon (MPR) eller mastektomi med sekundær rekonstruksjon (MSR). For de fleste brystkreftpasienter vil det være flere aktuelle kirurgiske metoder. Kunnskap om postoperativ livskvalitet, tilfredshet og komplikasjoner vil da kunne være veiledende ... -
Total and cause-specific standardized mortality ratios in patients with schizophrenia and/or substance use disorder
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-23)Individuals with schizophrenia or substance use disorder have a substantially increased mortality compared to the general population. Despite a high and probably increasing prevalence of comorbid substance use disorder in people with schizophrenia, the mortality in the comorbid group has been less studied and with contrasting results. We performed a nationwide open cohort study from 2009 to 2015, ... -
Springboard to an academic career—A national medical student research program
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-30)Over the last decades there has been a decline in the recruitment of medical students into academia in all medical fields. Concurrently, medical research has increasingly included other disciplines in multidisciplinary convergence, introducing an unmet recruitment gap and requirement for medical researchers. To counteract the trend and recruit students to academic medicine, a national intercalated ... -
Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-14)Background: The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with progression to end-stage renal disease (ESRD) in patients for whom prognosis could not be predicted based on clinical variables. <br> <br> Methods: Based on data from the Norwegian ... -
Dental caries and preterm birth: a systematic review and meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)Objectives:<br> The primary objective of this systematic review was to evaluate the association between dental caries and preterm birth (PTB). The secondary objective was ascertaining the difference between women with dental caries who experienced PTB and those who did not with regard to decayed, missing and filled teeth (DMFT), and decayed, missing and filled surfaces (DMFS) indices. <br>M ...
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