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dc.contributor.authorLoria, Marianna Ruiz
dc.contributor.authorGroessing, Alexander
dc.contributor.authorGuran, Alexandrina
dc.contributor.authorKoçan, Asena U.
dc.contributor.authorMikus, Nace
dc.contributor.authorNater, Urs M.
dc.contributor.authorKouwer, Karlijn
dc.contributor.authorPosserud, Maj-Britt Rocio
dc.contributor.authorSalomon-Gimmon, Maayan
dc.contributor.authorTodorova, Boryana
dc.contributor.authorWagner, Isabella C.
dc.contributor.authorGold, Christian
dc.contributor.authorSilani, Giorgia
dc.contributor.authorSpecht, Karsten
dc.date.accessioned2023-11-06T12:08:59Z
dc.date.available2023-11-06T12:08:59Z
dc.date.issued2023-10-02
dc.description.abstractThe notion of a connection between autism and music is as old as the first reported cases of autism, and music has been used as a therapeutic tool for many decades. Music therapy holds promise as an intervention for individuals with autism, harnessing their strengths in music processing to enhance communication and expression. While previous randomized controlled trials have demonstrated positive outcomes in terms of global improvement and quality of life, their reliance on psychological outcomes restricts our understanding of underlying mechanisms. This paper introduces the protocol for the Music for Autism study, a randomized crossover trial designed to investigate the effects of a 12-week music therapy intervention on a range of psychometric, neuroimaging, and biological outcomes in school-aged children with autism. The protocol builds upon previous research and aims to both replicate and expand upon findings that demonstrated improvements in social communication and functional brain connectivity following a music intervention. The primary objective of this trial is to determine whether music therapy leads to improvements in social communication and functional brain connectivity as compared to play-based therapy. In addition, secondary aims include exploring various relevant psychometric, neuroimaging, and biological outcomes. To achieve these objectives, we will enroll 80 participants aged 6–12 years in this international, assessor-blinded, crossover randomized controlled trial. Each participant will be randomly assigned to receive either music therapy or play-based therapy for a period of 12 weeks, followed by a 12-week washout period, after which they will receive the alternate intervention. Assessments will be conducted four times, before and after each intervention period. The protocol of the Music for Autism trial provides a comprehensive framework for studying the effects of music therapy on a range of multidimensional outcomes in children with autism. The findings from this trial have the potential to contribute to the development of evidence-based interventions that leverage strengths in music processing to address the complex challenges faced by individuals with autism.en_US
dc.identifier.citationLoria, Groessing, Guran, Koçan, Mikus, Nater, Kouwer, Posserud, Salomon-Gimmon, Todorova, Wagner, Gold, Silani, Specht. Music for autism: a protocol for an international randomized crossover trial on music therapy for children with autism. Frontiers in Psychiatry. 2023;14en_US
dc.identifier.cristinIDFRIDAID 2191435
dc.identifier.doi10.3389/fpsyt.2023.1256771
dc.identifier.issn1664-0640
dc.identifier.urihttps://hdl.handle.net/10037/31679
dc.language.isoengen_US
dc.publisherFrontiers Mediaen_US
dc.relation.journalFrontiers in Psychiatry
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleMusic for autism: a protocol for an international randomized crossover trial on music therapy for children with autismen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)