Vis enkel innførsel

dc.contributor.authorJohnsen, Liv-Hege
dc.contributor.authorHerder, Marit
dc.contributor.authorVangberg, Torgil Riise
dc.contributor.authorIsaksen, Jørgen Gjernes
dc.contributor.authorMathiesen, Ellisiv B.
dc.date.accessioned2023-12-12T08:43:47Z
dc.date.available2023-12-12T08:43:47Z
dc.date.issued2023-10-20
dc.description.abstractBackground: Data on prevalence of intracranial artery stenosis (ICAS) in Western populations is sparse. The aim of the study was to assess the prevalence and risk factors for ICAS in a mainly Caucasian general population. Methods: We assessed the prevalence of ICAS in 1847 men and women aged 40 to 84 years who participated in a cross-sectional population-based study, using 3-dimensional time-of-flight 3 Tesla magnetic resonance angiography. ICAS was defined as a focal luminal flow diameter reduction of ≥50 %. The association between cardiovascular risk factor levels and ICAS was assessed by multivariable regression analysis. Results: The overall prevalence of ICAS was 6.0 % (95 % confidence interval (CI) 5.0–7.2), 4.3 % (95 % CI 3.1–5.7) in women and 8.0 % (95 % CI 6.3–10.0) in men. The prevalence increased by age from 0.8 % in 40-54 years age group to 15.2 % in the 75-84 years age group. The majority of stenoses was located to the internal carotid artery (52.2 %), followed by the posterior circulation (33.1 %), the middle cerebral artery (10.8 %) and the anterior cerebral artery (3.8 %). The risk of ICAS was independently associated with higher age, male sex, hypertension, hyperlipidemia, diabetes mellitus, current smoking and higher BMI. Conclusions: The prevalence of ICAS in a general population of Caucasians was relatively high and similar to the prevalence of extracranial internal carotid artery stenosis in previous population-based studies.en_US
dc.identifier.citationJohnsen, Herder, Vangberg, Isaksen, Mathiesen. Prevalence of intracranial artery stenosis in a general population using 3D-time of flight magnetic resonance angiography. Journal of Stroke & Cerebrovascular Diseases. 2023;32(12)en_US
dc.identifier.cristinIDFRIDAID 2195959
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2023.107399
dc.identifier.issn1052-3057
dc.identifier.issn1532-8511
dc.identifier.urihttps://hdl.handle.net/10037/32020
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.ispartofJohnsen, L.H. (2024). Intracranial artery disease in the general population. (Doctoral thesis). <a href=https://hdl.handle.net/10037/33718>https://hdl.handle.net/10037/33718</a>
dc.relation.journalJournal of Stroke & Cerebrovascular Diseases
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titlePrevalence of intracranial artery stenosis in a general population using 3D-time of flight magnetic resonance angiographyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)