dc.contributor.author | Sagelv, Edvard Hamnvik | |
dc.contributor.author | Emaus, Nina Alice | |
dc.contributor.author | Evensen, Elin Kristin | |
dc.contributor.author | Christoffersen, Tore | |
dc.contributor.author | Dennison, Elaine | |
dc.contributor.author | Furberg, Anne-Sofie | |
dc.contributor.author | Grimnes, Guri | |
dc.contributor.author | Johansson, Jonas Lars | |
dc.contributor.author | Nielsen, Christopher Sivert | |
dc.contributor.author | Nilsen, Ole Andreas | |
dc.contributor.author | Winther, Anne | |
dc.date.accessioned | 2024-11-04T09:23:58Z | |
dc.date.available | 2024-11-04T09:23:58Z | |
dc.date.issued | 2024-07-03 | |
dc.description.abstract | Summary In a Norwegian youth cohort followed from adolescence to young adulthood, bone mineral density (BMD) levels
declined at the femoral neck and total hip from 16 to 27 years but continued to increase at the total body indicating a sitespecifc attainment of peak bone mass.<p>
<p>Purpose To examine longitudinal trends in bone mineral density (BMD) levels in Norwegian adolescents into young
adulthood.
<p>Method In a prospective cohort design, we followed 980 adolescents (473 (48%) females) aged 16–19 years into adulthood
(age of 26–29) on three occasions: 2010–2011 (Fit Futures 1 (FF1)), 2012–2013 (FF2), and 2021–2022 (FF3), measuring
BMD (g/cm<sup>2</sup>
) at the femoral neck, total hip, and total body with dual x-ray absorptiometry (DXA). We used linear mixed
models to examine longitudinal BMD changes from FF1 to FF3.
<p>Results From the median age of 16 years (FF1), femoral neck BMD (mean g/cm<sup>2</sup>
(95% CI)) slightly increased in females
from 1.070 (1.059–1.082) to 1.076 (1.065–1.088, p=0.015) at the median age of 18 years (FF2) but declined to 1.041
(1.029–1.053, p<0.001) at the median age of 27 years (FF3). Similar patterns were observed in males: 16 years, 1.104
(1.091–1.116); 27 years, 1.063 (1.050–1.077, p<0.001); and for the total hip in both sexes (both p<0.001). Total body BMD
increased from age 16 to 27 years in both sexes (females: 16 years, 1.141 (1.133–1.148); 27 years, 1.204 (1.196–1.212),
p<0.001; males: 16 years, 1.179 (1.170–1.188); 27 years, 1.310 (1.296–1.315), p<0.001).
<p>Conclusion BMD levels increased from 16 to 18 years at the femoral and total hip sites in young Norwegian females and
males, and a small decline was observed at the femoral sites when the participants were followed up to 27 years. Total body
BMD continued to increase from adolescence to young adulthood. | en_US |
dc.identifier.citation | Sagelv, Emaus, Evensen, Christoffersen, Dennison, Furberg, Grimnes, Johansson, Nielsen, Nilsen, Winther. Acquisition of peak bone mass in a Norwegian youth cohort : longitudinal findings from the Fit Futures study 2010–2022. Archives of Osteoporosis. 2024;19 | en_US |
dc.identifier.cristinID | FRIDAID 2289600 | |
dc.identifier.doi | 10.1007/s11657-024-01414-2 | |
dc.identifier.issn | 1862-3522 | |
dc.identifier.issn | 1862-3514 | |
dc.identifier.uri | https://hdl.handle.net/10037/35420 | |
dc.language.iso | eng | en_US |
dc.publisher | Springer Nature | en_US |
dc.relation.journal | Archives of Osteoporosis | |
dc.relation.uri | https://doi.org/10.1007/s11657-024-01414-2 | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2024 The Author(s) | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | en_US |
dc.rights | Attribution 4.0 International (CC BY 4.0) | en_US |
dc.title | Acquisition of peak bone mass in a Norwegian youth cohort : longitudinal findings from the Fit Futures study 2010–2022 | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |