With the current possible presence of thousands of PFAS compounds in industrial emissions, there is an increasing need to assess the impacts of PFAS regulation of conventional PFAS on one hand and the exposure to emerging and yet unknown PFAS on the other. Today’s analytical methodologies using targeted approaches are not sufficient to determine the complete suite of PFAS present. To evaluate the ...

<p><i>Background -</i> Adolescents may seek help for many reasons beyond health needs, such as personal stress due to violence exposure. <p><i>Objective -</i>To investigate factors associated with receiving professional assistance and informal help due to violence exposure in the community and at school. <p><i>Participants and setting -</i> This study was conducted in Itaboraí, a low-income ...

Background - The spread of the coronavirus in spring 2020 led to a lockdown of physical activity (PA) offers. The aim of this study was to investigate how PA, as well as general and mental health, in community-dwelling older adults were affected by the COVID-19 restrictions in Norway.<p> <p>Methods - Invitation to participate in the study was sent via Facebook and the Norwegian Pensioners’ ...

Background - Improvement in survival from pancreatic ductal adenocarcinoma (PDAC) has been reported in trial settings but is less explored in unselected cohorts. The aim of this study was to assess trends in provision of treatments and survival in Norway over a 15-year period following the implementation of hepato-pancreato-biliary (HPB) multidisciplinary teams, centralization of surgery, and ...

Children and adolescents have been severely affected by the COVID-19 pandemic. The aim of this study was to explore the prevalence of traditional and digital bullying and mental health problems a year into the pandemic. Further, how anxiety level, loneliness, and self-perceived school functioning have influenced the quality of life. A comprehensive questionnaire was administered (N = 1239) in the ...

Children and adolescents have been severely affected by the COVID-19 pandemic. The aim of this study was to explore the prevalence of traditional and digital bullying and mental health problems a year into the pandemic. Further, how anxiety level, loneliness, and self-perceived school functioning have influenced the quality of life. A comprehensive questionnaire was administered (N = 1239) in the ...

Background - I was a 42-year-old neurosurgeon with experience as department head when I took chair as chief executive officer (CEO) at the University Hospital of North Norway to lead a comprehensive organisational and financial restructuring. This article aims to develop lessons learnt during my 10-year tenure.<p> <p>Methods - I restructured the organisation and hired a new executive team. We ...

Biologisk kjønn har betydning for kliniske utfall, og kunnskap om kjønnsforskjeller i behandlingsutfall kan bidra til sikrere og mer tilpasset behandling for pasienter. Hensikten med denne kartleggingsoversikten var å undersøke bruken av kjønnsstratifiserte analyser i studier på effekt av behandling i en norsk sammenheng.<p> <p>Vi utførte en kartleggingsoversikt. Det er en type kunnskapsoppsummering ...

En nylig utført systematisk oversikt viste at det ikke finnes forskning som har undersøkt effekten av nasjonale og regionale, generelle melde- og varselordninger på alvorlige hendelser i helse- og omsorgstjenesten. Derfor var det hensiktsmessig å undersøke forskning som har sett på tilgrensende problemstillinger.<p> <p>Formålet med dette arbeidet var å kartlegge studier om mulige sammenhenger ...

Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ...