Low serum Apolipoprotein A1 (ApoA1) and high Apolipoprotein B (ApoB) are risk factors for the development of cardiovascular disease. Studies have found tracking of lipid and lipoprotein levels form childhood and youth, into adult life. In order to identify an unfavorable lipid profile in young ages, knowledge about the distribution of these biomarkers in the general population is a prerequisite. ...

Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood at LC diagnosis and evaluated, in pre-diagnostic blood specimens, how long before diagnosis expression changes of such candidate miRNAs could be detected. We identified upregulated ...

The use of dietary supplements (DS) is widespread and tends to increase with age and female gender. DS use can in some situations represent a safety risk for patients. For instance, concomitant use of medication and dietary supplements, particularly herbal remedies, may cause clinically significant pharmacological interactions. The study underlying this chapter aimed to investigate the prevalence ...

The present study examines the acoustic properties of infant-directed speech (IDS) as compared to adult-directed speech (ADS) in Norwegian parents of 18-month-old toddlers, and whether these properties relate to toddlers’ expressive vocabulary size. Twenty-one parent-toddler dyads from Tromsø, Northern Norway participated in the study. Parents (16 mothers, 5 fathers), speaking a Northern Norwegian ...

Early maladaptive schemas (EMSs) are broad and pervasive themes regarding oneself and one’s relationships with others originating from adverse childhood experiences. Although the concept of EMSs was initially developed for the treatment of personality disorders, the associations of EMSs with a variety of other mental disorders have been investigated. The goal of the present study was to summarize ...

<p><b> Study Design. </b> Exploratory subgroup analyses of a randomised trial (Antibiotics In Modic changes (AIM) study). <p><b> Objective. </b> To assess the effect of amoxicillin versus placebo in reducing Modic change (MC) oedema in patients with chronic low back pain (LBP). <p><b> Summary of Background Data. </b> The AIM study showed a small, clinically insignificant effect of ...

Animals that are moderately protein restricted respond to this dietary stress by increasing consumption of protein-containing foods. This is true in many species, including rodents. Rodent models of protein restriction have typically relied on only male subjects, and there are plausible reasons why female rodents may respond differently to dietary protein restriction. To address this gap in ...

Background The increasing number of patients surviving cancer leads to more people experiencing late and long term-effects from the disease and its treatment. Fatigue, sleep disorders, early menopause, pain, and nerve damage are commonly reported. Methods helping people to recover after cancer treatment are therefore essential. The aims of this study were threefold; (1) to determine the level of ...

Prevalence and medication rates of ADHD vary geographically, both between and within countries. No absolute cutof exists between ADHD and normal behavior, making clinician attitudes (leading to local practice cultures) a potential explanation for the observed variation in diagnosis and medication rates. The objective of this study was to describe variation in attitudes toward diagnosis and medication ...

It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of ...