Viser treff 1821-1840 av 10407

    • Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21 

      Anda, Erik Eik; Braaten, Tonje Bjørndal; Borch, Kristin Benjaminsen; Nøst, Therese Haugdahl; Chen, Sairah Lai Fa; Lukic, Marko; Lund, Eiliv; Forland, Frode; Leon, David Andrew; Askeland Winje, Brita; Kran, Anne-Marte Bakken; Kalager, Mette; Lund-Johansen, Fridtjof; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)
      Background: Since March 2020, 440 million people worldwide have been diagnosed with COVID-19, but the true number of infections with SARS-CoV-2 is higher. SARS-CoV-2 antibody seroprevalence can add crucial epidemiological information about population infection dynamics. Aim: To provide a large population-based SARS-CoV-2 seroprevalence survey from Norway; we estimated SARS-CoV-2 seroprevalence before ...
    • The Norwegian PraksisNett: a nationwide practice-based research network with a novel IT infrastructure 

      Kristoffersen, Espen Saxhaug; Bjorvatn, Bjørn; Halvorsen, Peder Andreas; Nilsen, Stein; Fossum, Guro Haugen; Fors, Egil Andreas; Jørgensen, Pål; Øxnevad-Gundersen, Berit; Gjelstad, Svein; Bellika, Johan Gustav; Straand, Jørund; Rørtveit, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-13)
      Clinical research in primary care is relatively scarce. Practice-based research networks (PBRNs) are research infrastructures to overcome hurdles associated with conducting studies in primary care. In Norway, almost all 5.4 million inhabitants have access to a general practitioner (GP) through a patient-list system. This gives opportunity for a PBRN with reliable information about the general ...
    • Introducing Lightweight IT – A Way to Build Flexibility for Healthcare Organizations? 

      Severinsen, Gro-Hilde; Silsand, Line; Malm-Nicolaisen, Kristian; Pedersen, Rune; Ellingsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      The paper addresses socio technical relations of implementing a lightweight IT app in Norway. The focus is on how such technology will influence the possibilities for an organization connected to a large-scale heavyweight IT infrastructure to provide more rapid changes in line with healthcare worker’s needs. The research question is therefore: How can lightweight IT support rapid organizational ...
    • Scaling AI Projects for Radiology– Causes and Consequences 

      Ellingsen, Gunnar; Silsand, Line; Severinsen, Gro-Hilde; Linstad, Line Helen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Artificial intelligence (AI) for radiology has the potential to handle an ever-increasing volume of imaging examinations. However, the implementation of AI for clinical practice has not lived up to expectations. We suggest that a key problem with AI projects in radiology is that high expectations associated with new and unproven AI technology tend to scale the projects in ways that challenge their ...
    • Pain, discomfort, and functional impairment after extraction of primary teeth in children with palatally displaced canines–a randomized control trial comparing extraction of the primary canine versus extraction of the primary canine and the primary first molar 

      Hadler-Olsen, Sigurd; Steinnes, Jeanett; Nermo, Hege; Sjögren, Anders; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
      Objective - To assess pain, discomfort, and functional impairment in children experiencing extraction of primary canine or primary canine and primary first molar as an interceptive treatment for palatally displaced permanent canines.<p> <p>Material and methods - Twenty-eight children, aged 9.5–14 years with displaced permanent maxillary canines were randomly assigned for extraction of the primary ...
    • Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis 

      Hudson, Jemma; Cruickshank, Moira; Quinton, Richard; Aucott, Lorna; Aceves-Martins, Magaly; Gillies, Katie; Bhasin, Shalender; Snyder, Peter J; Ellenberg, Susan S; Grossmann, Mathis; Travison, Thomas G; Gianatti, Emily J; van der Schouw, Yvonne T; Emmelot-Vonk, Marielle H; Giltay, Erik J; Hackett, Geoff; Ramachandran, Sudarshan; Svartberg, Johan; Hildreth, Kerry L; Groti Antonic, Kristina; Brock, Gerald B; Tenover, J Lisa; Tan, Hui Meng; Kong, Christopher Ho Chee; Tan, Wei Shen; Marks, Leonard S; Ross, Richard J; Schwartz, Robert S; Manson, Paul; Roberts, Stephen; Andersen, Marianne; Magnussen, Line Velling; Hernández, Rodolfo; Oliver, Nick; Wu, Frederick; Dhillo, Waljit S; Bhattacharya, Siladitya; Brazzelli, Miriam; Jayasena, Channa N (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
      Background Testosterone is the standard treatment for male hypogonadism, but there is uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide the most extensive individual participant dataset (IPD) of testosterone trials available, to analyse subtypes of all cardiovascular events observed during treatment, and to investigate the effect of incorporating data ...
    • Sexual Harassment and Abuse among Young Elite Athletes, Recreational Athletes, and Reference Students: A Prospective Study 

      Sølvberg, Nina; Torstveit, Monica Klungland; Rosenvinge, Jan H; Pettersen, Gunn; Sundgot-Borgen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11)
      Purpose: To examine the 12-months prevalence and 12-months prospective change in reported sexual harassment and abuse (SHA)-victimization among young elite athletes, recreational athletes, and reference students in three different social settings and identify the perpetrators. Methods: In total, 919 adolescents responded to an online questionnaire in 12th grade (T1) and 13th grade (T2). The ...
    • Alterations in genetically modified crops assessed by omics studies: Systematic review and meta-analysis 

      Benevenuto, Rafael Fonseca; Venter, Hermoine Jean; Zanatta, Caroline Bedin; Nodari, Rubens Onofre; Agapito-Tenfen, Sarah Zanon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-04)
      Background International agreements and domestic legislation regulate genetically modified (GM) crops for environmental release, recognizing that genetic engineering could result in unintended genotypic and phenotypic effects. In that context, omics technologies, which allow comprehensive characterization of the molecular profile of GM crops at all levels, may be used to assess alterations or effects ...
    • Approaches to studying: changes during a three-year undergraduate study program 

      Mørk, Gry; Gramstad, Astrid; Åsli, Lene Angel; Stigen, Linda; Johnson, Susanne Grødem; Magne, Trine A; Carstensen, Tove; Småstuen, Milada Cvancarova; Bonsaksen, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-21)
      Whether higher education students’ approaches to studying are amenable to change, is disputed. In this study, Norwegian occupational therapy students’ (n = 263) approaches to studying were assessed annually across the three-year course, with the aim of exploring changes during the undergraduate study program. Sociodemographic information and the Approaches and Study Skills Inventory for Students ...
    • Geographical variation in orthopedic procedures in Norway: Cross-sectional population-based study 

      Holsen, Maria; Hovind, Veronica; Bedane, Haji Kedir; Osvoll, Knut Ivar; Gjertsen, Jan-Erik; Furnes, Ove Nord; Walsh, Mary E.; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)
      Background: Standardized surgery rates for common orthopedic procedures vary across geographical areas in Norway. We explored whether area-level factors related to demand and supply in publicly funded healthcare are associated with geographical variation in surgery rates for six common orthopedic procedures.<p> <p>Methods: The present study is a cross-sectional population-based study of hospital ...
    • The risk factors for radial artery and saphenous vein graft occlusion are different 

      Bahar, Ramez; Hermansen, Stig Eggen; Dahl-Eriksen, Øystein; Busund, Rolf; Dahl, Per Erling; Iqbal, Amjid; Mannsverk, Jan Torbjørn; Myrmel, Truls; Steigen, Terje; Trovik, Thor; Sørlie, Dag Glen; Bartnes, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-02)
      Objectives. To determine risk factors for radial artery and saphenous vein graft occlusion during long-term follow-up after coronary artery bypass grafting (CABG). Methods: From a cohort of 119 patients who had received a radial artery graft, 76 – of whom 55 also had at least one saphenous vein graft – underwent a preplanned direct angiography and anthropometric, biochemical, and endothelial ...
    • History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors 

      Bramness, Jørgen Gustav; Pandey, Susmita; Moe, Jenny Skumsnes; Toft, Helge Prytz; Lien, Lars; Bolstad, Ingeborg (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-13)
      Introduction: Delirium tremens (DT) occurs after stopping prolonged, high alcohol intake and may be life-threatening if untreated. We need to know about clinical correlates of DT in order to provide the best clinical care.<p> <p>Methods: At admission to inpatient treatment a cohort of 114 alcohol use disorder (AUD) patients were interviewed and examined concerning psychiatric diagnosis and symptoms, ...
    • Alcohol and aging: A longitudinal study of alcohol habits and health effects due to alcohol consumption in old adulthood 

      Stelander, Line Tegner (Doctoral thesis; Doktorgradsavhandling, 2022-12-15)
      Alcohol use is a leading risk factor for injuries, mortality and the burden of disease. Alcohol consumption among older adults varies considerably, depending on factors such as age, social class, education, ethnicity, time period and geographical setting. Furthermore, the health effects associated with alcohol consumption in old age are an under researched area. The overall aim of this thesis was ...
    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial 

      Johansen, Jeanette Schultz; Halvorsen, Kjell H.; Svendsen, Kristian; Havnes, Kjerstin; Robinson, Eirin Guldsten; Ljones Wetting, Hilde; Haustreis, Stine; Småbrekke, Lars; Kamycheva, Elena; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      Background - Suboptimal medication use contributes to a substantial proportion of hospitalizations and emergency department visits in older adults. We designed a clinical pharmacist intervention to optimize medication therapy in older hospitalized patients. Based on the integrated medicine management (IMM) model, the 5-step IMMENSE intervention comprise medication reconciliation, medication review, ...
    • Chitinolytic enzymes contribute to the pathogenicity of Aliivibrio salmonicida LFI1238 in the invasive phase of cold-water vibriosis 

      Skåne, Anna; Edvardsen, Per Kristian Thorén; Cordara, Gabriele; Loose, Jennifer Sarah Maria; Leitl, Kira Daryl; Krengel, Ute; Sørum, Henning; Askarian, Fatemeh; Vaaje-Kolstad, Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-08)
      Background - Aliivibrio salmonicida is the causative agent of cold-water vibriosis in salmonids (Oncorhynchus mykiss and Salmo salar L.) and gadidae (Gadus morhua L.). Virulence-associated factors that are essential for the full spectrum of A. salmonicida pathogenicity are largely unknown. Chitin-active lytic polysaccharide monooxygenases (LPMOs) have been indicated to play roles in both chitin ...
    • Normalization of gene expression data revisited: the three viewpoints of the transcriptome in human skeletal muscle undergoing load-induced hypertrophy and why they matter 

      Khan, Yusuf; Hammarström, Daniel; Ellefsen, Stian; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-18)
      Background - The biological relevance and accuracy of gene expression data depend on the adequacy of data normalization. This is both due to its role in resolving and accounting for technical variation and errors, and its defining role in shaping the viewpoint of biological interpretations. Still, the choice of the normalization method is often not explicitly motivated although this choice may be ...
    • Enactive explorations of children's sensory-motor play and therapeutic handling in physical therapy 

      Håkstad, Ragnhild B.; Øberg, Gunn Kristin; Girolami, Gay L.; Dusing, Stacey C (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-11)
      Introduction: In pediatric physical therapy, there is an ongoing debate about the use of therapeutic handling and its potential effects on motor learning. In this study, we build on enactive theoretical perspectives to explore the role of therapeutic handling in connection to children's sensory-motor play, engagement, and performance during a single physical therapy session.<p> <p>Material and ...
    • Cold exposure and musculoskeletal conditions; A scoping review 

      Farbu, Erlend Hoftun; Höper, Anje Christina; Reierth, Eirik; Nilsson, Tohr; Skandfer, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Background: Musculoskeletal conditions are major contributors to years lived with disability. Cold exposure can be a risk factor, but any conclusion is obscure.<p> <p>Aim: The aim of the present scoping review was to identify the existing evidence of an association between cold exposure and musculoskeletal conditions. The aim also included to consider pain in different regions and their assessment, ...
    • Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial 

      Nilsson, Magnus; Olafsdottir, Halla; Alexandersson von Döbeln, Gabriella; Villegas, Fernanda; Gagliardi, Giovanna; Hellström, Mats; Wang, Qiao-Li; Johansson, Hemming; Gebski, Val; Hedberg, Jakob; Klevebro, Fredrik; Markar, Sheraz; Smyth, Elizabeth; Lagergren, Pernilla; Al-Haidari, Ghazwan Ahmed Dhia Eldin; Rekstad, Lars Cato; Aahlin, Eirik Kjus; Wallner, Bengt; Edholm, David; Johansson, Jan; Szabo, Eva; Reynolds, John V.; Pramesh, C.S.; Mummudi, Naveen; Joshi, Amit; Ferri, Lorenzo; Wong, Rebecca KS; O’Callaghan, Chris; Lukovic, Jelena; Chan, Kelvin KW; Leong, Trevor; Barbour, Andrew; Smithers, Mark; Li, Yin; Kang, Xiaozheng; Kong, Feng-Ming; Chao, Yin-Kai; Crosby, Tom; Bruns, Christiane; van Laarhoven, Hanneke; van Berge Henegouwen, Mark; van Hillegersberg, Richard; Rosati, Riccardo; Piessen, Guillaume; de Manzoni, Giovanni; Lordick, Florian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      <b><p>Background:</b> The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment leads to around 60% overall 5-year survival, yet with impaired postsurgical quality of life. Observational studies indicate that curatively intended chemoradiotherapy, ...
    • Ecological Bodies and Relational Anatomies: Toward a Transversal Foundation for Planetary Health Education 

      Richter, Robert; Maric (PhD), Filip (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
      As planetary health education enters medical and health professional training, transversal implementation across curricula is critical in developing its full potential and enabling future health professionals to meet the social, environmental, and health challenges of current and future generations in an integrated manner. To advance the transversal implementation of planetary health education, our ...