Patient and public involvement (PPI) in research has the potential to improve research validity and relevance. Objectives: To explore how PPI has been carried out and how its impacts have been reported in occupational therapy (OT) health research. Methodology: Scoping review based on a search in four databases for OT research with descriptions of PPI, published between 2010 and 2020. Results: Across ...

Circumpolar Indigenous populations continue to experience dramatic health inequities when compared to their national counterparts. The objectives of this study are first, to explore the space given in the existing literature to the concepts of cultural safety and cultural competence, as it relates to Indigenous peoples in Circumpolar contexts; and second, to document where innovations have emerged. ...

The present thesis is a study of how doctors learn to make clinical decisions; decisions about diagnosis and therapy of the individual patient in the context of the clinic. It is based on ethnographic fieldwork and anthropological analysis carried out in 2006-2009. The key informants are nine doctors who go through internship and the empirical field is the wards and clinics of regional hospitals, ...

Persistent toxic substances like organochlorines (OCs) and certain toxic metals have been or are extensively used, and can be globally distributed by long-range transport. The fetus and growing child are exposed via the placenta and breast milk and are vulnerable to their negative health effects. Concentrations measured in maternal blood or breast milk are thus potential indicators of risk for ...

This thesis highlights several clinically important questions related to bone loss the first year following stroke and with regard to bone mass at stroke onset:<br> Lack of mobility and weight bearing early after stroke is an important factor for the greater bone loss in the proximal femur on the paretic side. Relearning to walk within the first two month after stroke, even with support of another ...

When this thesis was planned in 2000-2001 it was well known that bone loss accelerates after menopause, and is prevented by using hormone replacement therapy (HRT). Case reports of young men with estrogen receptor dysfunction or aromatase deficiency showed that estrogen was important for normal growth and maturation of the male skeleton. However, there were few prospective studies examining the ...

Both substance use and substance use disorders (SUDs) are common problems suffered by patients seeking primary care. Since its second volume in 1985,1 Family Practice has continually highlighted research related to detecting and treating legal, illegal, and prescription substance use, abuse, and dependence. Twenty-five years later, many of the same research questions and clinical challenges still ...

Background: The need for a stability evaluation of [ ¹⁸F]FDG is evident. The main purpose of this study was to make recommendations for determining the shelf life based on the available stability literature and our own two-centre stability studies.<p> <p>Results: We performed a non-systematic literature study to fnd the most relevant stability data for [ ¹⁸F]FDG. The amount ...

Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat invading microorganisms. Understanding the expression of long non-coding RNAs containing Alu elements in inflammation is important for reconstructing ...

Objectives: Impedance cardiography (ICG) is a non-invasive method for continuous cardiac output measurement and has the potential to improve monitoring and treatment of sick neonates. PhysioFlow® is a signal-morphology ICG-system showing promising results in adults with low and high cardiac output, but no data from neonates or neonatal models exist. The aim of this study was to investigate PhysioFlow® ...