Det helsevitenskapelige fakultet: Nye registreringer

Viser treff 2781-2800 av 10433

    • To tolerate weather and to tolerate pain: two sides of the same coin? The Tromsø Study 7 

      Farbu, Erlend Hoftun; Rypdal, Martin; Skandfer, Morten; Steingrimsdottir, Olöf Anna; Brenn, Tormod; Stubhaug, Audun; Nielsen, Christopher Sivert; Höper, Anje Christina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-09)
      It is a common belief that weather affects pain. Therefore, we hypothesized that weather can affect pain tolerance. This study used data from over 18,000 subjects aged 40 years or older from the general population, who participated in the Tromsø Study 7. They underwent a one-time assessment of cuff algometry pressure pain tolerance (PPT) and cold pain tolerance (CPT), tested with a cold pressor test. ...

    • Cesarean sections in Georgia and Norway - What contributes to too much, too little, or just right? The role of maternal risk factors and efforts to reduce high cesarean section rates 

      Nedberg, Ingvild Hersoug (Doctoral thesis; Doktorgradsavhandling, 2022-04-06)
      High rates of cesarean section are associated with increased mortality and morbidity. To decrease cesarean sections without medical indication is complex and requires in-depth knowledge of local context and which groups to target for possible interventions. Our aim was to assess the role of maternal risk factors in relation to cesarean section in Georgia and Norway, two countries with diverging rates ...

    • Validation of a graded prognostic model in patients with brain metastases treated with whole-brain radiotherapy instead of radiosurgery 

      Nieder, Carsten; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05)
      Background/Aim: The aim of this study was to analyze the survival predictions obtained from a recent graded prognostic model developed and validated in Japan.<p><p> Patients and Methods: This was a retrospective single-institution analysis of 249 patients, managed with whole-brain radiotherapy for brain metastases. The sum of scores was calculated as in the Japanese study. The following parameters ...

    • Joint Effect of Multiple Prothrombotic Genotypes and Obesity on the Risk of Incident Venous Thromboembolism 

      Frischmuth, Tobias; Hindberg, Kristian; Gabrielsen, Maiken Elvestad; Brumpton, Ben Michael; Hveem, Kristian; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-03)
      <p><b>Background</b> The impact of the combination of obesity and multiple prothrombotic genotypes on venous thromboembolism (VTE) risk remains unclear. <p><b>Objective</b> To investigate the joint effect of obesity and a genetic risk score (GRS) composed of established prothrombotic single nucleotide polymorphisms (SNPs) on VTE risk using a population-based case–cohort. <p><b>Methods</b> Cases ...

    • Novel Biomarkers of Habitual Alcohol Intake and Associations With Risk of Pancreatic and Liver Cancers and Liver Disease Mortality 

      Loftfield, Erikka; Stepien, Magdalena; Viallon, Vivian; Trijsburg, Laura; Rothwell, Joseph A.; Robinot, Nivonirina; Biessy, Carine; Bergdahl, Ingvar A.; Bodén, Stina; Schulze, Matthias B.; Bergman, Manuela; Weiderpass, Elisabete; Schmidt, Julie A.; Zamora-Ros, Raúl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Sonestedt, Emily; Ohlsson, Bodil; Katzke, Verena; Kaaks, Rudolf; Ricceri, Fulvio; Tjønneland, Anne; Dahm, Christina C.; Sánchez, Maria-Jose; Trichopoulou, Antonia; Tumino, Rosario; Chirlaque, María-Dolores; Masala, Giovanna; Ardanaz, Eva; Vermeulen, Roel; Brennan, P; Albanes, Demetrius; Weinstein, Stephanie J.; Scalbert, Augustin; Freedman, Neal D.; Gunter, Marc; Jenab, Mazda; Sinha, Rashmi; Keski-Rahkonen, Pekka; Ferrari, Pietro (Preprint; Manuskript, 2021-05-19)
      Background - Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed because of measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.<p> <p>Methods - Untargeted metabolomics was used to identify metabolites correlated with ...

    • A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC 

      Papadimitriou, Nikos; Bouras, Emmanouil; van den Brandt, Piet A.; Muller, David C.; Papadopoulou, Areti; Heath, Alicia K.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Ferrari, Pietro; Weiderpass, Elisabete; Boeing, Heiner; Bastide, Nadia; Merritt, Melissa A.; Lopez, David S.; Bergmann, Manuela M.; Perez-Cornago, Aurora; Schulze, Matthias; Skeie, Guri; Srour, Bernard; Eriksen, Anne Kirstine; Boden, Stina; Johansson, Ingegerd; Nøst, Therese Haugdahl; Lukic, Marko; Ricceri, Fulvio; Ericson, Ulrika; Huerta, José-Maria; Dahm, Christina C.; Agnoli, Claudia; Amiano, Pilar; Tjønneland, Anne; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Ardanaz, Eva; Berntsson, Jonna; Sánchez, Maria-Jose; Tumino, Rosario; Panico, Salvatore; Katzke, Verena; Jakszyn, Paula; Masala, Giovanna; Derksen, Jeroen W.G.; Quirós, J. Ramón; Severi, Gianluca; Cross, Amanda J.; Riboli, Ellio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
      Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p> <p>Methods - The association ...

    • Palliative radiotherapy during the last month of life: Have COVID-19 recommendations led to reduced utilization? 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01)
      Background/Aim: The study aimed to evaluate practice changes in the time period of the early wave of the COVID-19 pandemic. Patients and Methods: This was a retrospective single institution study. We defined palliative radiotherapy (PRT) initiated before Saturday, March 14th as pre-COVID and PRT initiated later as during-COVID (through June 30th). Results: National COVID-19 recommendations ...

    • Cerebroplacental ratio in predicting adverse perinatal outcome: a meta-analysis of individual participant data 

      Vollgraff Heidweiller-Schreurs, Heidweiller-Schreurs; van Osch, Osch; Heymans, Martijn W.; Ganzevoort, Wessel; Schoonmade, L.J.; Bax, C.J.; Mol, Ben W.; de Groot, Christianne J.M.; Bossuyt, Patrick M.M.; de Boer, Boer; Khalil, Asma; Thilaganathan, Basky; Turan, Ozhan M; Crimmins, Sarah; Harman, Chris; Shannon, Alisson M; Kumar, Sailesh; Dicker, Patrick; Malone, Fergal; Tully, Elizabeth C; Unterscheider, Julia; Crippa, Isabella; Ghidini, Alessandro; Roncaglia, Nadia; Vergani, Patrizia; Bhide, Amar; D'Antonio, Francesco; Pilu, Gianluigi; Galindo, Alberto; Herraiz, Ignacio; Vázquez-Sarandeses, Alicia; Ebbing, Cathrine; Johnsen, Synnøve Lian; Karlsen, Henriette Odland (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-03)
      Objective To investigate if cerebroplacental ratio (CPR) adds to the predictive value of umbilical artery pulsatility index (UA PI) alone – standard of practice – for adverse perinatal outcome in singleton pregnancies.<p> <p>Design and setting Meta-analysis based on individual participant data (IPD).<p> <p>Population or sample Ten centres provided 17 data sets for 21 661 participants, 18 731 ...

    • Sex-steroids and social network in relation to Staphylococcus aureus nasal carriage 

      Stensen, Dina Benedicte Berg (Doctoral thesis; Doktorgradsavhandling, 2022-04-01)
      <i>Staphylococcus aureus</i> (<i>S. aureus</i>) is a human pathogen that can colonize skin and mucosa. Nasal carriage is associated with increased risk of autoinfection and transmission and it is therefore important to identify possible targets for prevention of carriage. Sex and age are the most important risk factors for <i>S. aureus</i> carriage, and hypotheses about sex-steroids as major host ...

    • Elevated plasma D-dimer levels are associated with risk of future incident venous thromboembolism 

      Hansen, Ellen-Sofie; Rinde, Fridtjof Balteskard; Edvardsen, Magnus; Hindberg, Kristian; Latysheva, Nadezhda; Aukrust, Pål; Ueland, Thor; Michelsen, Annika Elisabet; Hansen, John Bjarne; Brækkan, Sigrid Kufaas; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-25)
      <p><i>Background</i> D-dimer, a global biomarker for activation of the coagulation and fibrinolysis systems, is useful in assessing individual risk of venous thromboembolism (VTE) recurrence. However, there is limited information on the association between D-dimer and risk of a first lifetime VTE event. <p><i>Objectives</i> To investigate the association between plasma D-dimer levels and risk of ...

    • Plasma concentrations of persistent organic pollutants and pancreatic cancer risk 

      Porta, Miquel; Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Agudo, Antoni; Rylander, Charlotta; Nøst, Therese Haugdahl; Donat-Vargas, Carolina; Aune, Dagfinn; Heath, Alicia K; Cirera, Lluís; Goni-Irigoyen, Fernando; Alguacil, Juan; Giménez-Robert, Álex; Tjønneland, Anne; Sund, Malin; Overvad, Kim; Romana Mancini, Francesca; Rebours, Vinciane; Boutron-Ruault, Marie Christine; Kaaks, Rudolf; Schulze, Matthias B.; Trichopoulou, Antonia; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Vermeulen, Roel; Ramón Quirós, J; Rodríguez-Barranco, Miguel; Colorado-Yohar, Sandra M.; Chirlaque, María Dolores; Ardanaz, Eva; Wareham, Nick; Key, Tim; Johansson, Mattias; Murphy, Neil; Ferrari, Pietro; Huybrechts, Inge; Chajes, Veronique; Gonzalez, Carlos Alberto; de Mesquita, Bas Bueno; Gunter, Marc; Vainio, Elisabete Weiderpass; Riboli, Elio; Duell, Eric J; Katzke, Verena; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-14)
      Background: Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts.<p> Methods: We conducted a prospective case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Participants were 513 pancreatic cancer cases and 1020 matched ...

    • Staphylococcus aureus bloodstream infections: Diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU/EEA, 2005 to 2018 

      Gagliotti, Carlo; Högberg, Liselotte Diaz; Billström, Hanna; Eckmanns, Tim; Giske, Christian G.; Heuer, Ole E.; Jarlier, Vincent; Kahlmeter, Gunnar; Wong, Danilo Lo Fo; Monen, Jos; Murchan, Stephen; Simonsen, Gunnar Skov; Šubelj, Maja; Andrašević, Arjana Tambić; Żabicka, Dorota; Žemličková, Helena; Monnet, Dominique L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-18)
      Background: Invasive infections caused by Staphylococcus aureus have high clinical and epidemiological relevance. It is therefore important to monitor the S. aureus trends using suitable methods. Aim: The study aimed to describe the trends of bloodstream infections (BSI) caused by meticillin-resistant S. aureus (MRSA) and meticillin-susceptible S. aureus (MSSA) in the European Union (EU) and the ...

    • Assessing the impact of exposome on the course of chronic obstructive pulmonary disease and cystc fibrosis: The REMEDIA European Project Approach 

      Benjdir, Manon; Audureau, Etienne; Beresniak, Ariel; Coll, Patrice; Epaud, Ralph; Fiedler, Kristina; Jacquemin, B; Niddam, Laurent; Pandis, Spyros N.; Pohlmann, Gerhard; Sandanger, Torkjel M; Simmons, Kai; Sorensen, Mette; Wagner, Patrick; Lanone, Sophie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Because of the direct interaction of lungs with the environment, respiratory diseases are among the leading causes of environment-related deaths in the world. Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are two highly debilitating diseases that are of particular interest in the context of environmental studies; they both are characterized by a similar progressive loss of ...

    • “I’m not the doctor; I’m just the patient”: Patient agency and shared decision-making in naturally occurring primary care consultations 

      Lian, Olaug S; Nettleton, Sarah; Grange, Huw R.; Dowrick, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-30)
      Objectives: To explore interactional processes in which clinical decisions are made in situ during medical consultations, particularly the ways in which patients show agency in decision-making processes by proposing and opposing actions, and which normative dimensions and role-expectations their engagement entail.<p> Methods: Narrative analysis of verbatim transcripts of 22 naturally occurring ...

    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...

    • Does the Stereotypicality of Mothers’ Occupation Influence Children’s Communal Occupational Aspirations and Communal Orientation? 

      Kvalø, Marie; Olsen, Marte; Thorsteinsen, Kjærsti; Olsson, Maria; Martiny, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-16)
      Career development is a lifelong process that starts in infancy and is shaped by a number of different factors during childhood, adolescence, and adulthood. Even though career development is shaped through life, relatively little is known about the predictors of occupational aspirations in childhood. Therefore, in the present work we investigate how the stereotypicality of a mother’s occupation ...

    • Terrengsykling og kjønnsrepresentasjoner. En studie om fremstilling av kjønn i magasinet 'Terrengsykkel' 

      Iwarsson, Annichen Emilia Andvig (Master thesis; Mastergradsoppgave, 2021-12-21)
      Terrengsykling er en stadig voksende aktivitet både internasjonalt og nasjonalt. I denne oppgaven har jeg undersøkt problemstillinger knyttet til fremstillinger av kjønnsrepresentasjoner i magasinet ‘Terrengsykkel’. Studien belyser hvordan kjønn blir fremstilt gjennom tekst og bilder i magasinet. Min problemstilling har vært: Hvilke kjønnsrepresentasjoner og betydninger av kjønn utrykkes i magasinet ...

    • The LabBM score is an excellent survival prediction tool in patients undergoing palliative radiotherapy 

      Nieder, Carsten; Dalhaug, Astrid; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-16)
      Background and aim: The prognostic assessment of patients referred for palliative radiotherapy can be conducted by sitespecific scores. A quick assessment that would cover the whole spectrum could simplify the working day of clinicians who are not specialists for a particular disease site. This study evaluated a promising score, the LabBM (validated for brain metastases), in patients treated for ...

    • Cognitive impairment in older cancer patients treated with first-line chemotherapy 

      Dos Santos, Mélanie; Licaj, Idlir; Bellera, Carine; Cany, Laurent; Binarelli, Giulia; Soubeyran, Pierre; Joly, Florence (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      Older cancer patients are vulnerable to chemotherapy-related cognitive impairment. We prospectively evaluated cognitive impairment and its predictive factors during first-line chemotherapy in elderly cancer patients (≥70 years). Cognitive function was evaluated by the Mini-Mental State Examination (MMSE) with adjusted scores for age and sociocultural level. Multidimensional geriatric assessment was ...

    • Kennedy disease in two sisters with biallelic CAG expansions of the androgen receptor gene 

      Müller, Kai Ivar; Nilssen, Øivind; Nebuchenykh, Maria; Løseth, Sissel; Jonsrud, Christoffer; Hoem, Gry; Van Ghelue, Marijke; Arntzen, Kjell Arne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-19)
      We present a retrospective 21-year follow-up of two sisters with X-linked biallelic CAG expansions in the androgen receptor (AR) gene causing Kennedy disease. Two sisters inherited CAG expansions from their mother who was a carrier and their father who had Kennedy disease. Genetic testing revealed alleles comprising 43/45, and 43/43 CAG repeats in the younger and older sister, respectively. They ...