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norskDet helsevitenskapelige fakultet: Nye registreringer
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Expanding general practice with interprofessional teams: a mixed-methods patient perspective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-30)Background Across healthcare systems, current health policies promote interprofessional teamwork. Compared to single-profession general practitioner care, interprofessional primary healthcare teams are expected to possess added capacity to care for an increasingly complex patient population. This study aims to explore patients’ experiences when their usual primary healthcare encounter with general ... -
The impact of COVID-19-related restrictions on pregnancy and abortion rates in the Republic of Georgia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-18)Background The Republic of Georgia implemented COVID-19-related restrictions starting on 31 March 2020, when it imposed a 1-month strict lockdown, after which the country continued with some form of restrictions for 1 year. These restrictions created barriers to healthcare access, affected healthcare services, caused severe economic degradation, and changed reproductive behavior. The aim of this ... -
Genomic insights into Enterococcus faecium isolates from marine bivalves highlight One Health concerns and healthcare linkages
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-12)Enterococci, especially Enterococcus faecium, are one of today’s leading causes of multidrug-resistant infections in hospital settings. The marine environment may harbour enterococci, but its role as an evolutionary niche and as a vector for the spread of enterococci is sparsely investigated. Hence, by applying enterococci in bivalves as a sentinel tool, this study aimed to describe the prevalence ... -
Post-traumatic stress disorder among heart disease patients: a clinical follow-up of individuals with myocardial infarction in the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-12)Background Myocardial infarction is likely to be experienced as a life-threatening and potentially traumatic event. Approximately one-third of patients with myocardial infarction experience clinically significant symptoms of anxiety/ depression. However, it is unclear how many of these patients experience these symptoms because of post-traumatic stress disorder (PTSD). We conducted a clinical screening ... -
Change characteristics of health-related quality of life and its association with post-stroke fatigue at four-year follow-up
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-04)The long-term consequences of stroke may be highly individual and multifaceted. The question of how such individual differences may unfold and change beyond the first year after stroke may be of substantial clinical interest regarding which subgroups show more favourable and unfavourable rehabilitation trajectories. The current study explored functional trajectories from 1 to 4 years post-stroke ... -
The Delta III and Delta Xtend reverse shoulder arthroplasty. Risk of revision and failure mechanisms: a report on 3,650 cases from the Norwegian Arthroplasty Register 1994-2021
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-15)Background - The Delta reverse shoulder arthroplasty (RSA) is commonly used worldwide and is the most frequently used RSA in Norway. The aim of this registry-based study was to report 10- and 20-year implant survival, risk of revision, and reasons for revision in 2 consecutive time periods for Delta III (1994-2010) and Delta Xtend (2007-2021) prostheses.<p> <p>Methods - We included 3650 primary ... -
The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by circulating global hospital-associated clones
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-19)Between 2010 and 2015 the incidence of vancomycin-resistant Enterococcus faecium (VREfm) in Norway increased dramatically. Hence, we selected (1) a random subset of vancomycin-resistant enterococci (VRE) from the Norwegian Surveillance System for Communicable Diseases (2010–15; n=239) and (2) Norwegian vancomycin-susceptible E. faecium (VSEfm) bacteraemia isolates from the national surveillance ... -
Panoramic radiograph analyses for early detection of osteoporosis in the population of Northern Norway
(Doctoral thesis; Doktorgradsavhandling, 2024-01-26)Osteoporosis is a chronic disease affecting bone tissue that may lead to fractures from minor accidents. Roughly 20% of females and 6 % of males have osteoporosis after age 50, but the disease might be present at a younger age. Early diagnosis is challenging because the disease has no symptoms. Dental radiography is a frequent examination that might be useful for early osteoporosis screening at ... -
Mapping of systematic reviews on traditional medicine across health conditions: A protocol for a systematic map
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-11)Introduction - Traditional medicine (TM) is an important part of healthcare either as the main healthcare system or as a complement to conventional medicine. The effectiveness of TM has been assessed in clinical trials that have been synthesised into thousands of systematic reviews (SRs). This study is commissioned by the World Health Organization (WHO) and is aimed at providing a systematic map of ... -
Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-04)Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity in the mammary epithelium is reflected in extensive heterogeneity among breast cancers. Here, we have analyzed RNA-sequencing data from three different mammary epithelial cell ... -
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)Background - Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal clinical studies that include biomarker negative healthy controls and cases with established AD pathology. Here, we employ longitudinally sampled cerebrospinal fluid (CSF) core AD, ... -
Association between atmospheric air temperature and blood pressure among adult population in different seasons
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-17)BACKGROUND: The prevalence of hypertension in the Arkhangelsk region is steadily increasing. Despite the progress in the diagnostics and the availability of treatment, a half of the population are unaware of their hypertension and its potential consequences, and consequently, do not adhere to the prescribed medications. This lack of awareness, coupled with the challenging climatic conditions of the ... -
Barriers and facilitators to national guideline implementation for palliative cancer care in a Danish cross-sectoral healthcare setting: A qualitative study of healthcare professionals' experiences
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-11)Objective - Patients with incurable cancer should receive general palliative care according to their needs, as provided through collaboration between hospital departments, municipalities, and general practices and as outlined in national guidelines. However, the implementation of general palliative care in Denmark has been inadequate. This study aimed to investigate the healthcare professionals' ... -
Prevensjonsveiledning etter fødsel og jordmors rolle. En kvalitativ studie om jordmødres opplevelser av prevensjonsveiledning etter fødsel og deres rolle
(Master thesis; Mastergradsoppgave, 2023-03-13)<p>Hensikt: Å undersøke hvordan jordmødre opplever å prevensjonsveilede etter fødsel og hvordan de anser egen rolle. <p>Problemstilling: “Jordmødres opplevelser av prevensjonsveiledning etter fødsel og deres rolle” <p>Metode: Det ble anvendt et kvalitativt forskningsdesign. Det ble gjennomført ni dybdeintervjuer med jordmødre som jobbet med prevensjonsveiledning på føde/barselavdeling på sykehus- ... -
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-22)Background - Older adults are at greater risk of medication-related harm than younger adults. The Integrated Medication Management model is an interdisciplinary method aiming to optimize medication therapy and improve patient outcomes.<p> <p>Objective - We aimed to investigate the cost effectiveness of a medication optimization intervention compared to standard care in acutely hospitalized older ... -
Kunnskapsoppsummering og klassifisering av tiltaket: TFCO - Treatement Foster Care Oregon (1. utg.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-13)Bakgrunn: Treatment Foster Care Oregon (TFCO) er en behandlingsmetode for ungdommer med alvorlige atferdsvansker og deres familier. Overordnet er målene å oppnå gode behandlingsresultater på ungdommens vansker, og at ungdommene skal kunne bo hjemme hos foreldrene. TFCO er en multisystemisk, koordinert behandlingsform, der man arbeider med flere relevante arenaer for ungdommen parallelt, som for ... -
Faktorer som påvirker forebygging av stikkskader i operasjonsfeltet - en litteraturstudie
(Mastergradsoppgave; Master thesis, 2022-11-04)Abstrakt Tittel: Faktorer som påvirker bruk av tiltak og metoder for forebygging av stikkskader i operasjonsfeltet – en litteraturstudie Bakgrunn: Operasjonssykepleierne håndterer daglig skarpe gjenstander i det det sterile operasjonsfeltet. Hensikten med denne masteroppgaven er å bidra til mer kunnskap og forståelse av hvordan ulike faktorer påvirker handlingsgrunnlaget for forebygging av ... -
Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-22)Background - Many community-acquired pleural infections are caused by facultative and anaerobic bacteria from the human oral microbiota. The epidemiology, clinical characteristics, pathogenesis, and etiology of such infections are little studied. The aim of the present prospective multicenter cohort study was to provide a thorough microbiological and clinical characterization of such oral-type pleural ... -
Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited observational evidence, we investigated whether prediagnostic Se status and/or variants in the selenoprotein genes are associated with BC risk in a large European cohort. Se status was assessed by plasma measures of Se and its major circulating proteins, selenoprotein P (SELENOP) and glutathione peroxidase 3 (GPX3), in ... -
Nye sentre skal gi flere kliniske studier i Norge
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-20)Seks NorTrials-sentre for behandlingsforskning er etablert ved universitetssykehusene. Målet er å øke antallet kliniske studier og forbedre pasientbehandlingen.
