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dc.contributor.authorBooth, Andrew
dc.contributor.authorLewin, Simon Arnold
dc.contributor.authorGlenton, Claire
dc.contributor.authorMunthe-Kaas, Heather Menzies
dc.contributor.authorToews, Ingrid
dc.contributor.authorNoyes, Jane
dc.contributor.authorRashidian, Arash
dc.contributor.authorBerg, Rigmor
dc.contributor.authorNyakang’o, Brenda
dc.contributor.authorMeerpohl, Jörg J.
dc.date.accessioned2019-03-19T12:41:38Z
dc.date.available2019-03-19T12:41:38Z
dc.date.issued2018-01-25
dc.description.abstract<p><i>Background</i>: The GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research) approach has been developed by the GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group. The approach has been developed to support the use of findings from qualitative evidence syntheses in decision-making, including guideline development and policy formulation.</p> <p>CERQual includes four components for assessing how much confidence to place in findings from reviews of qualitative research (also referred to as qualitative evidence syntheses): (1) methodological limitations, (2) coherence, (3) adequacy of data and (4) relevance. This paper is part of a series providing guidance on how to apply CERQual and focuses on a probable fifth component, dissemination bias. Given its exploratory nature, we are not yet able to provide guidance on applying this potential component of the CERQual approach. Instead, we focus on how dissemination bias might be conceptualised in the context of qualitative research and the potential impact dissemination bias might have on an overall assessment of confidence in a review finding. We also set out a proposed research agenda in this area.</p> <p><i>Methods</i>: We developed this paper by gathering feedback from relevant research communities, searching MEDLINE and Web of Science to identify and characterise the existing literature discussing or assessing dissemination bias in qualitative research and its wider implications, developing consensus through project group meetings, and conducting an online survey of the extent, awareness and perceptions of dissemination bias in qualitative research.</p> <p><i>Results</i>: We have defined dissemination bias in qualitative research as a systematic distortion of the phenomenon of interest due to selective dissemination of studies or individual study findings. Dissemination bias is important for qualitative evidence syntheses as the selective dissemination of qualitative studies and/or study findings may distort our understanding of the phenomena that these syntheses aim to explore and thereby undermine our confidence in these findings.</p> <p>Dissemination bias has been extensively examined in the context of randomised controlled trials and systematic reviews of such studies. The effects of potential dissemination bias are formally considered, as publication bias, within the GRADE approach. However, the issue has received almost no attention in the context of qualitative research. Because of very limited understanding of dissemination bias and its potential impact on review findings in the context of qualitative evidence syntheses, this component is currently not included in the GRADE-CERQual approach.</p> <p><i>Conclusions</i>: Further research is needed to establish the extent and impacts of dissemination bias in qualitative research and the extent to which dissemination bias needs to be taken into account when we assess how much confidence we have in findings from qualitative evidence syntheses.</p>en_US
dc.description.sponsorshipThe Alliance for Health Policy and Systems Research, WHO The Department of Reproductive Health and Research, WHO Norad (Norwegian Agency for Development Cooperation The Research Council of Norway The Cochrane Methods Innovation Fund The South African Medical Research Councilen_US
dc.descriptionSource at <a href=https://doi.org/10.1186/s13012-017-0694-5> https://doi.org/10.1186/s13012-017-0694-5</a>. Licensed <a href=http://creativecommons.org/licenses/by-nc-nd/4.0/> CC BY-NC-ND 4.0.</a>en_US
dc.identifier.citationBooth, A., Lewin, S., Glenton, C., Munthe-Kaas, H.M., Toews, I., Noyes, J., ... Meerpohl, J.J. (2018). Applying GRADE-CERQual to qualitative evidence synthesis findings-paper 7: Understanding the potential impacts of dissemination bias. <i>Implementation Science, 13</i>(12). https://doi.org/10.1186/s13012-017-0694-5en_US
dc.identifier.cristinIDFRIDAID 1581873
dc.identifier.doi10.1186/s13012-017-0694-5
dc.identifier.issn1748-5908
dc.identifier.urihttps://hdl.handle.net/10037/15022
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalImplementation Science
dc.relation.projectIDThe Research Council of Norway: ?en_US
dc.relation.urihttps://implementationscience.biomedcentral.com/track/pdf/10.1186/s13012-017-0694-5
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800en_US
dc.subjectVDP::Social science: 200::Political science and organizational theory: 240en_US
dc.subjectVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240en_US
dc.subjectQualitative researchen_US
dc.subjectQualitative evidence synthesisen_US
dc.subjectSystematic review methodologyen_US
dc.subjectResearch designen_US
dc.subjectMethodologyen_US
dc.subjectConfidenceen_US
dc.subjectEvidence-based practiceen_US
dc.subjectDissemination biasen_US
dc.subjectPublication biasen_US
dc.subjectGRADEen_US
dc.titleApplying GRADE-CERQual to qualitative evidence synthesis findings–paper 7: understanding the potential impacts of dissemination biasen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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