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dc.contributor.authorFlohr-Madsen, Sandra
dc.contributor.authorYtrebø, Lars Marius
dc.contributor.authorKregnes, Sylvia Beate
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorKlaastad, Øivind
dc.date.accessioned2019-05-10T07:41:02Z
dc.date.available2019-05-10T07:41:02Z
dc.date.issued2013-02-18
dc.description.abstract<p><i>Background - </i>Ultrasound guidance has been shown to reduce the minimum effective volume (MEV) of local anaesthetics for several peripheral nerve blocks. Although the lateral sagittal infraclavicular block (LSIB) is a well‐established anaesthesia method, MEV for this technique has not been established. Our aim with this study was to determine the MEV using ropivacaine 7.5 mg/ml for the LSIB method. <p><i>Methods - </i>Twenty‐five adult American Society of Anesthesiologists physical status I‐II patients scheduled for hand surgery received an ultrasound‐guided LSIB with ropivacaine 7.5 mg/ml. A successful block was defined as anaesthesia or analgesia for all five sensory nerves distal to the elbow, 30 min after local anaesthetic injection. The MEV for a successful block in 50% of the patients was determined by using the staircase up‐and‐down method introduced by Dixon and Massey. Logistic regression and probit transformation were applied to estimate the MEV for a successful block in 95% of the patients. <p><i>Results - </i>The patients received ropivacaine 7.5 mg/ml volumes in the range of 12.5–30 ml. The MEVs in 50% and 95% of the patients were 19 ml [95% confidence interval (CI), 14–27] and 31 ml (95% CI, 18–45), respectively. <p><i>Conclusions - </i>For surgery distal to the elbow, the MEV in 95% of patients for an ultrasound‐guided LSIB with ropivacaine 7.5 mg/ml was estimated to be 31 ml (95% CI, 18–45 ml). Further studies should determine the factors that influence the volume of local anaesthetic required for a successful infraclavicular block.en_US
dc.descriptionThis is the peer reviewed version of the following article: Flohr-Madsen, S., Ytrebø, L.M., Kregnes, S.B., Wilsgaard, T. & Klaastad, Ø. (2013). Minimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus block. <i>Acta Anaesthesiologica Scandinavica, 57</i>(4), 495-501, which has been published in final form at <a href=https://doi.org/10.1111/aas.12078>https://doi.org/10.1111/aas.12078</a>. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en_US
dc.identifier.citationFlohr-Madsen, S., Ytrebø, L.M., Kregnes, S.B., Wilsgaard, T. & Klaastad, Ø. (2013). Minimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus block. <i>Acta Anaesthesiologica Scandinavica, 57</i>(4), 495-501. https://doi.org/10.1111/aas.12078en_US
dc.identifier.cristinIDFRIDAID 1033184
dc.identifier.doi10.1111/aas.12078
dc.identifier.issn0001-5172
dc.identifier.issn1399-6576
dc.identifier.urihttps://hdl.handle.net/10037/15276
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofFlohr-Madsen, S. (2019). Studies of peripheral nerve blocks for hand and shoulder surgery. (Doctoral thesis). <a href=https://hdl.handle.net/10037/15264>https://hdl.handle.net/10037/15264</a>
dc.relation.journalActa Anaesthesiologica Scandinavica
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Anesthesiology: 765en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Anestesiologi: 765en_US
dc.titleMinimum effective volume of ropivacaine 7.5mg/ml for an ultrasound-guided infraclavicular brachial plexus blocken_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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