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dc.contributor.authorPietropaolo, Valeria
dc.contributor.authorPrezioso, Carla
dc.contributor.authorMoens, Ugo
dc.date.accessioned2020-08-19T06:22:58Z
dc.date.available2020-08-19T06:22:58Z
dc.date.issued2020-07-03
dc.description.abstractViruses are the cause of approximately 15% of all human cancers. Both RNA and DNA human tumor viruses have been identified, with Merkel cell polyomavirus being the most recent one to be linked to cancer. This virus is associated with about 80% of Merkel cell carcinomas, a rare, but aggressive cutaneous malignancy. Despite its name, the cells of origin of this tumor may not be Merkel cells. This review provides an update on the structure and life cycle, cell tropism and epidemiology of the virus and its oncogenic properties. Putative strategies to prevent viral infection or treat virus-positive Merkel cell carcinoma patients are discussed.en_US
dc.identifier.citationPietropaolo, Prezioso, Moens u. Merkel Cell Polyomavirus and Merkel Cell Carcinoma. Cancers. 2020;12(7)en_US
dc.identifier.cristinIDFRIDAID 1820068
dc.identifier.doihttps://doi.org/10.3390/cancers12071774
dc.identifier.issn2072-6694
dc.identifier.urihttps://hdl.handle.net/10037/19030
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalCancers
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700en_US
dc.subjectVDP::Medisinske Fag: 700en_US
dc.titleMerkel Cell Polyomavirus and Merkel Cell Carcinomaen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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