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dc.contributor.authorGarratt, Andrew
dc.contributor.authorFurunes, Håvard
dc.contributor.authorHellum, Christian
dc.contributor.authorSolberg, Tore
dc.contributor.authorBrox, Jens Ivar
dc.contributor.authorStorheim, Kjersti
dc.contributor.authorJohnsen, Lars Gunnar
dc.date.accessioned2021-08-05T09:27:53Z
dc.date.available2021-08-05T09:27:53Z
dc.date.issued2021-05-28
dc.description.abstract<p>Background: The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. Evidence from healthy and sick populations shows that the additional two response categories improve measurement properties but there has not been a concurrent comparison of the two versions in patients with low back pain (LBP). <p>Methods: LBP patients taking part in a multicenter randomized controlled trial of lumbar total disc replacement and conservative treatment completed the EQ-5D-3L and 5L in an eight-year follow-up questionnaire. The 3L and 5L were assessed for aspects of data quality including missing data, floor and ceiling effects, response consistency, and based on a priori hypotheses, associations with the Oswestry Disability Index (ODI), Pain-Visual Analogue Scales and Hopkins Symptom Checklist (HSCL-25). <p>Results: At the eight-year follow-up, 151 (87%) patients were available and 146 completed both the 3L and 5L. Levels of missing data were the same for the two versions. Compared to the EQ-5D-5L, the 3L had significantly higher floor (pain discomfort) and ceiling effects (mobility, self-care, pain/discomfort, anxiety/depression). For these patients the EQ-5D-5L described 73 health states compared to 28 for the 3L. Shannon’s indices showed the 5L outperformed the 3L in tests of classification efficiency. Correlations with the ODI, Pain-VAS and HSCL-25 were largely as hypothesized, the 5L having slightly higher correlations than the 3L. <p>Conclusion: The EQ-5D assesses important aspect of health in LBP patients and the 5L improves upon the 3L in this respect. The EQ-5D-5L is recommended in preference to the 3L version, however, further testing in other back pain populations together with additional measurement properties, including responsiveness to change, is recommended.en_US
dc.identifier.citationGarratt AM, Furunes, Hellum, Solberg, Brox, Storheim, Johnsen. Evaluation of the EQ-5D-3L and 5L versions in low back pain patients. Health and Quality of Life Outcomes. 2021;19:155:1-9en_US
dc.identifier.cristinIDFRIDAID 1915915
dc.identifier.doi10.1186/s12955-021-01792-y
dc.identifier.issn1477-7525
dc.identifier.urihttps://hdl.handle.net/10037/21949
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.relation.journalHealth and Quality of Life Outcomes
dc.relation.projectIDinfo:eu-repo/grantAgreement/RCN/HELSEVEL-H/262673/Norway/Elicitation of a Norwegian EuroQol EQ-5D value set for the economic evaluation of health care programs//en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Epidemiology medical and dental statistics: 803en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803en_US
dc.titleEvaluation of the EQ-5D-3L and 5L versions in low back pain patientsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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