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dc.contributor.authorJørgensen, Helle
dc.contributor.authorHorváth-Puhó, Erzsébet
dc.contributor.authorLaugesen, Kristina
dc.contributor.authorBrækkan, Sigrid
dc.contributor.authorHansen, John-Bjarne
dc.contributor.authorSørensen, Henrik Toft
dc.date.accessioned2021-11-23T08:49:02Z
dc.date.available2021-11-23T08:49:02Z
dc.date.issued2021-09-09
dc.description.abstractBackground: Although venous thromboembolism (VTE) is a leading cause of morbidity and mortality, and socioeconomic status (SES) affects human health and health behavior, few studies have examined the association between SES and VTE. Objectives: We aimed to investigate the association between SES, assessed individually and in a composite score by levels of education, income, and employment status, and incident VTE.<p> <p>Methods: We used Danish national registries to identify 51 350 persons aged 25– 65 years with incident VTE during 1995–2016. For each case, we used incidence density sampling to select five age-, sex-, and index-year-matched controls from the general Danish population (n = 256 750). SES indicators, including education, income, and employment status, were assessed 1 and 5 years before the VTE. We used conditional logistic regression to compute odds ratios (ORs) with 95% confidence intervals (CIs) for VTE according to individual SES indicators and a composite SES score in analyses adjusted for age, sex, and comorbidities.<p> <p>Results: Compared with low levels, high educational level (OR 0.74; 95% CI 0.71– 0.77), high income (OR 0.70; 95% CI 0.68–0.72), and high employment status (OR 0.66; 95% CI 0.64–0.68) were associated with decreased risk of VTE, even after adjusting for comorbidities. A composite SES score was superior to the individual indicators in assessing VTE risk (OR for high vs. low score: 0.61; 95% CI 0.59–0.63). In sensitivity analysis with SES indicators measured 5 years before the VTE, the risk estimates remained essentially the same.<p> <p>Conclusion: High levels of both individual SES indicators and a composite SES score were associated with decreased VTE risk.en_US
dc.identifier.citationJørgensen H, Horváth-Puhó, Laugesen, Brækkan, Hansen, Sørensen. Socioeconomic status and risk of incident venous thromboembolism. Journal of Thrombosis and Haemostasis. 2021en_US
dc.identifier.cristinIDFRIDAID 1942487
dc.identifier.doi10.1111/jth.15523
dc.identifier.issn1538-7933
dc.identifier.issn1538-7836
dc.identifier.urihttps://hdl.handle.net/10037/23120
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofJørgensen, H. (2022). The impact of socioeconomic status on the risk and prognosis of venous thromboembolism. (Doctoral thesis). <a href=https://hdl.handle.net/10037/27047>https://hdl.handle.net/10037/27047</a>.
dc.relation.journalJournal of Thrombosis and Haemostasis
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775en_US
dc.titleSocioeconomic status and risk of incident venous thromboembolismen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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