Vis enkel innførsel

dc.contributor.authorKjønås, Didrik
dc.contributor.authorSchirmer, Henrik
dc.contributor.authorMalm, Siri
dc.contributor.authorEidet, Jo
dc.contributor.authorAaberge, Lars
dc.contributor.authorSteigen, Terje
dc.contributor.authorAakhus, Svend
dc.contributor.authorBusund, Rolf
dc.contributor.authorRøsner, Assami
dc.contributor.authorDahle, Gry
dc.date.accessioned2022-01-31T13:13:53Z
dc.date.available2022-01-31T13:13:53Z
dc.date.issued2021-05-06
dc.description.abstractObjectives: Transcatheter aortic valve implantation (TAVI)-specific risk scores have been developed based on large registry studies. Our aim was to evaluate how both surgical and novel TAVI risk scores performed in predicting all cause 30-day mortality. In addition, we wanted to explore the validity of our own previously developed model in a separate and more recent cohort.<p> <p>Methods: The derivation cohort included patients not eligible for open surgery treated with TAVI at the University Hospital of North Norway (UNN) and Oslo University Hospital (OUS) from February 2010 through June 2013. From this cohort, a logistic prediction model (UNN/OUS) for all cause 30-day mortality was developed. The validation cohort consisted of patients not included in the derivation cohort and treated with TAVI at UNN between June 2010 and April 2017. EuroSCORE, Logistic EuroSCORE, EurosSCORE 2, STS score, German AV score, OBSERVANT score, IRRMA score, and FRANCE-2 score were calculated for both cohorts. The discriminative accuracy of each score, including our model, was evaluated by receiver operating characteristic (ROC) analysis and compared using DeLong test where P< .05 was considered statistically significant.<p> <p>Results: The derivation cohort consisted of 218 and the validation cohort of 241 patients. Our model showed statistically significant better accuracy than all other scores in the derivation cohort. In the validation cohort, the FRANCE-2 had a significantly higher predictive accuracy compared to all scores except the IRRMA and STS score. Our model showed similar results.<p> <p>Conclusion: Existing risk scores have shown limited accuracy in predicting early mortality after TAVI. Our results indicate that TAVI-specific risk scores might be useful when evaluating patients for TAVI.en_US
dc.identifier.citationKjønås, Dahle G, Schirmer, Malm, Eidet, Aaberge, Steigen, Aakhus, Busund, Røsner. Risk scores for prediction of 30-day mortality after transcatheter aortic valve implantation: Results from a two-center study in Norway. Health Science Reports. 2021;4en_US
dc.identifier.cristinIDFRIDAID 1967667
dc.identifier.doi10.1002/hsr2.283
dc.identifier.issn2398-8835
dc.identifier.urihttps://hdl.handle.net/10037/23850
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofKjønås, D. (2022). Prediction of outcome in patients with severe aortic stenosis treated with transcatheter aortic valve implantation. (Doctoral thesis). <a href=https://hdl.handle.net/10037/25298>https://hdl.handle.net/10037/25298</a>.
dc.relation.journalHealth Science Reports
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.titleRisk scores for prediction of 30-day mortality after transcatheter aortic valve implantation: Results from a two-center study in Norwayen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel