Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management.
Permanent lenke
https://hdl.handle.net/10037/23936Dato
2021-05-14Type
Journal articleTidsskriftartikkel
Peer reviewed
Forfatter
Cook, Sarah; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Malyutina, S; Shapkina, M; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, JKSammendrag
Methods: The study population was a sub-sample of participants aged 40–69 years participating in the Know Your Heart (KYH) study in Russia in 2015–18 (n=1883) and in the 7th survey of the Tromsø Study (n=5271) carried out in Norway in 2015–16 (Tromsø 7) who participated in spirometry examinations. The main outcome was obstructive lung function (FEV1/FVC ratio< lower limit of normal on pre-bronchodilator spirometry examination) with and without respiratory symptoms (chronic cough and breathlessness). In those with obstructive lung function, awareness (known diagnosis) and management (use of medications, smoking cessation) were compared.
Results: The age-standardized prevalence of obstructive lung function was similar among men in both studies (KYH 11.0% vs Tromsø 7 9.8%, p=0.21) and higher in the Norwegian (9.4%) than Russian (6.8%) women (p=0.006). In contrast, the prevalence of obstructive lung function plus respiratory symptoms was higher in Russian men (KYH 8.3% vs Tromsø 7 4.7%, p<0.001) but similar in women (KYH 5.9% vs Tromsø 7 6.4%, p=0.18). There was a much higher prevalence of respiratory symptoms in Russian than Norwegian participants of both sexes regardless of presence of obstructive lung function.
Conclusion: The prevalence of respiratory symptoms was strikingly high among Russian participants but this was not explained by a higher burden of obstructive lung function on spirometry testing in comparison with Norwegian participants. Further work is needed to understand the reasons and health implications of this high prevalence of cough and breathlessness.