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dc.contributor.authorAngenete, Oskar W
dc.contributor.authorAugdal, Thomas Angell
dc.contributor.authorRygg, Marite
dc.contributor.authorRosendahl, Karen
dc.date.accessioned2022-02-08T15:03:29Z
dc.date.available2022-02-08T15:03:29Z
dc.date.issued2021-11-19
dc.description.abstractRationale and Objectives: The temporomandibular joint (TMJ) is commonly involved in children with juvenile idiopathic arthritis. The diagnosis and evaluation of the disease progression is dependent on medical imaging. The precision of this imaging is under debate. SeveralR scoring systems have been proposed but transparent testing of the precision of the constituents of the scoring systems is lacking. The present study aims to test the precision of 25 imaging features based on magnetic resonance imaging (MRI).<p> <p>Materials and Methods: Clinical data and imaging were obtained from the Norwegian juvenile idiopathic arthritis study, The NorJIA study. Twenty-five imaging features of the TMJ in MRI datasets from 86 study participants were evaluated by two experienced radiologists for inter- and intraobserver agreement. Agreement of ordinal variables was measured with Cohen s linear or weighted Kappa as appropriate. Agreement of continuous measurements was assessed with 95% limit of agreement according to Bland-Altman.<p> <p>Results: In the osteochondral domain, the ordinal imaging variables “loss of condylar volume,” “condylar shape,” “condylar irregularities,” “shape of the eminence/fossa,” “disk abnormalities,” and “condylar inclination” showed inter- and intraobserver agreement above Kappa 0.5. In the inflammatory domain, the ordinal imaging variables “joint fluid,” “overall impression of inflammation,” “synovial enhancement” and “bone marrow oedema” showed inter- and intraobserver agreement above Kappa 0.5. Continuous measurements performed poorly with wide limits of agreement.<p> <p>Conclusion: A precise MRI-based scoring system for assessment of TMJ in JIA is proposed consisting of seven variables in the osteochondral domain and four variables in the inflammatory domain. Further testing of the clinical validity of the variables is needed.en_US
dc.identifier.citationAngenete O, Augdal Ta, Rygg, Rosendahl. MRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring System. Academic Radiology. 2021en_US
dc.identifier.cristinIDFRIDAID 1963712
dc.identifier.doi10.1016/j.acra.2021.09.024
dc.identifier.issn1076-6332
dc.identifier.issn1878-4046
dc.identifier.urihttps://hdl.handle.net/10037/23969
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalAcademic Radiology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Association of University Radiologistsen_US
dc.subject.hrcsBetennelse og immunsystem: Evaluering av markører og teknologier
dc.subject.hrcsInflammatory and Immune System: Evaluation of markers and technologies
dc.titleMRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring Systemen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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