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dc.contributor.authorNieder, Carsten
dc.contributor.authorDalhaug, Astrid
dc.contributor.authorHaukland, Ellinor Christin
dc.date.accessioned2022-03-09T13:05:54Z
dc.date.available2022-03-09T13:05:54Z
dc.date.issued2021-08-16
dc.description.abstractBackground and aim: The prognostic assessment of patients referred for palliative radiotherapy can be conducted by sitespecific scores. A quick assessment that would cover the whole spectrum could simplify the working day of clinicians who are not specialists for a particular disease site. This study evaluated a promising score, the LabBM (validated for brain metastases), in patients treated for other indications.<p> <p>Materials and methods: The LabBM score was calculated in 375 patients by assigning 1 point each for C-reactive protein and lactate dehydrogenase above the upper limit of normal, and 0.5 points each for hemoglobin, platelets and albumin below the lower limit of normal. Uni- and multivariate analyses were performed.<p> Results: Median overall survival gradually decreased with increasing point sum (range 25.1–1.1 months). When grouped according to the original three-tiered model, excellent discrimination was found. Patients with 0–1 points had a median survival of 15.7 months. Those with 1.5–2 points had a median survival of 5.8 months. Finally, those with 2.5–3.5 points had a median survival of 3.2 months (all p-values ≤ 0.001).<p> Conclusion: The LabBM score, which is derived from inexpensive blood tests and easy to use, stratified patients into three very distinct prognostic groups and deserves further validation.en_US
dc.identifier.citationNieder C, Dalhaug A, Haukland E. The LabBM score is an excellent survival prediction tool in patients undergoing palliative radiotherapy. Reports of Practical Oncology and Radiotherapy. 2021;26(5):740-746en_US
dc.identifier.cristinIDFRIDAID 1966926
dc.identifier.doi10.5603/RpOR.a2021.0096
dc.identifier.issn1507-1367
dc.identifier.issn2083-4640
dc.identifier.urihttps://hdl.handle.net/10037/24355
dc.language.isoengen_US
dc.publisherVia Medicaen_US
dc.relation.journalReports of Practical Oncology and Radiotherapy
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 Greater Poland Cancer Centreen_US
dc.titleThe LabBM score is an excellent survival prediction tool in patients undergoing palliative radiotherapyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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