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dc.contributor.authorMjåset, Christer
dc.contributor.authorSolberg, Tore
dc.contributor.authorZwart, John Anker Henrik
dc.contributor.authorSmåstuen, Milada Cvancarova
dc.contributor.authorKolstad, Frode
dc.contributor.authorGrotle, Margreth
dc.date.accessioned2023-01-09T08:34:46Z
dc.date.available2023-01-09T08:34:46Z
dc.date.issued2022-12-08
dc.description.abstractPurpose By using data from the Norwegian Registry for Spine Surgery, we wanted to develop and validate prediction models for non-success in patients operated with anterior surgical techniques for cervical degenerative radiculopathy (CDR).<p> <p>Methods This is a multicentre longitudinal study of 2022 patients undergoing CDR surgery and followed for 12 months to fnd prognostic models for non-success in neck disability and arm pain using multivariable logistic regression analysis. Model performance was evaluated by area under the receiver operating characteristic curve (AUC) and a calibration test. Internal validation by bootstrapping re-sampling with 1000 repetitions was applied to correct for over-optimism. The clinical usefulness of the neck disability model was explored by developing a risk matrix for individual case examples. <p>Results Thirty-eight percent of patients experienced non-success in neck disability and 35% in arm pain. Loss to follow-up was 35% for both groups. Predictors for non-success in neck disability were high physical demands in work, low level of education, pending litigation, previous neck surgery, long duration of arm pain, medium-to-high baseline disability score and presence of anxiety/depression. AUC was 0.78 (95% CI, 0.75, 0.82). For the arm pain model, all predictors for non-success in neck disability, except for anxiety/depression, were found to be signifcant in addition to foreign mother tongue, smoking and medium-to-high baseline arm pain. AUC was 0.68 (95% CI, 0.64, 0.72). <p>Conclusion The neck disability model showed high discriminative performance, whereas the arm pain model was shown to be acceptable. Based upon the models, individualized risk estimates can be made and applied in shared decision-making with patients referred for surgical assessment.en_US
dc.identifier.citationMjåset, Solberg, Zwart, Småstuen, Kolstad, Grotle. Anterior surgical treatment for cervical degenerative radiculopathy: a prediction model for non-success. Acta Neurochirurgica. 2022:1-13en_US
dc.identifier.cristinIDFRIDAID 2097350
dc.identifier.doi10.1007/s00701-022-05440-2
dc.identifier.issn0001-6268
dc.identifier.issn0942-0940
dc.identifier.urihttps://hdl.handle.net/10037/28070
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.journalActa Neurochirurgica
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleAnterior surgical treatment for cervical degenerative radiculopathy: a prediction model for non-successen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)