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dc.contributor.authorZwartkruis, VW
dc.contributor.authorSharashova, Ekaterina
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorDe Boer, RA
dc.contributor.authorLøchen, Maja-Lisa
dc.contributor.authorRienstra, Michiel
dc.date.accessioned2023-01-11T12:26:08Z
dc.date.available2023-01-11T12:26:08Z
dc.date.issued2022-09-01
dc.description.abstractObjectives - Shift work is associated with myocardial infarction and stroke. We studied if shift work is also associated with incident atrial fibrillation (AF) and if this association differs, depending on sex and age.<p> <p>Methods - We studied 22 339 participants (age 37.0±9.8 years, 49% women) with paid work from the third (1986–1987), fourth (1994–1995), fifth (2001) and sixth (2007–2008) surveys of the population-based Tromsø Study, Norway. Participants were followed up for ECG-confirmed AF through 2016. Shift work was assessed by questionnaire at each survey. We used unadjusted and multivariable-adjusted Cox regression models to study the association of shift work with 10-year incident AF and incident AF during extensive follow-up up to 31 years. Interactions with sex and age were tested in the multivariable model.<p> <p>Results - Shift work was reported by 21% of participants at the first attended survey. There was an interaction between shift work and age for 10-year incident AF (p=0.069). When adjusted for AF risk factors, shift work was significantly associated with 10-year incident AF in participants <40 years (HR 2.90, 95% CI 1.12 to 7.49) but not≥40 years of age (HR 0.90, 95% CI 0.53 to 1.51). Shift work was not associated with incident AF during extensive follow-up (HR 1.03, 95% CI 0.89 to 1.20). There was no interaction between shift work and sex.<p> <p>Conclusions - Shift work was associated with 10-year incident AF in individuals <40 years but not ≥40 years of age. Shift work was not associated with incident AF during extensive follow-up up to 31 years, and there were no sex differences.<p>en_US
dc.identifier.citationZwartkruis, Sharashova EE, Wilsgaard T, De Boer R, Løchen M, Rienstra M. Shift work is associated with 10-year incidence of atrial fibrillation in younger but not older individuals from the general population: results from the Tromsø Study. Open heart. 2022;9(e002086)en_US
dc.identifier.cristinIDFRIDAID 2100913
dc.identifier.doi10.1136/openhrt-2022-002086
dc.identifier.issn2053-3624
dc.identifier.urihttps://hdl.handle.net/10037/28155
dc.language.isoengen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.journalOpen heart
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0en_US
dc.rightsAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)en_US
dc.titleShift work is associated with 10-year incidence of atrial fibrillation in younger but not older individuals from the general population: results from the Tromsø Studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Except where otherwise noted, this item's license is described as Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)