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dc.contributor.authorGram, Emma Grundtvig
dc.contributor.authorManso, Túlia Filipa Roberto
dc.contributor.authorHeleno, Bruno
dc.contributor.authorSiersma, Volkert
dc.contributor.authorá Rogvi, Jessica
dc.contributor.authorBrodersen, John
dc.date.accessioned2023-08-18T10:15:34Z
dc.date.available2023-08-18T10:15:34Z
dc.date.issued2023-06-07
dc.description.abstractObjective - Ductal carcinoma in situ (DCIS) is a risk factor for invasive breast cancer (IBC). The prognosis of DCIS is considerably better than for IBC, yet women do not distinguish between the threat. We aimed to compare the psychosocial consequences of screen-detected DCIS and IBC, and to examine this comparison over time.<p> <p>Methods - We surveyed a Danish mammography-screening cohort from 2004 to 2018. We assessed outcomes at six-time points: baseline, 1, 6, 18, 36 months, and 14 years after the screening. We measured psychosocial consequences with the Consequences Of Screening – Breast Cancer (COS-BC): a condition-specific questionnaire that is psychometrically validated and encompasses 14 psychosocial dimensions. We used weighted linear models with generalized estimating equations to compare responses between groups. We used a 1% level of significance.<p> <p>Results - 170 out of 1309 women were diagnosed with breast cancer (13.0%). 23 were diagnosed with DCIS (13.5%) and 147 with IBC (86.5%). From baseline to six months after diagnosis, there were no significant differences between women with DCIS and IBC. However, mean scores indicated that IBC generally was more affected than DCIS. After six months, we observed that women with DCIS and IBC might be affected differently in the long term; mean scores and mean differences showed that IBC were more affected on some scales, while DCIS were on others.<p> <p>Conclusion - Overall, the DCIS and IBC experienced similar levels of psychosocial consequences. Women might benefit from renaming DCIS to exclude cancer nomenclature.en_US
dc.identifier.citationGram, Manso, Heleno, Siersma, á Rogvi, Brodersen. The long-term psychosocial consequences of screen-detected ductal carcinoma in situ and invasive breast cancer. Breast. 2023;70:41-48en_US
dc.identifier.cristinIDFRIDAID 2157829
dc.identifier.doi10.1016/j.breast.2023.06.003
dc.identifier.issn0960-9776
dc.identifier.issn1532-3080
dc.identifier.urihttps://hdl.handle.net/10037/30078
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalBreast
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleThe long-term psychosocial consequences of screen-detected ductal carcinoma in situ and invasive breast canceren_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)