Institutt for klinisk medisin: Recent submissions

Now showing items 1241-1260 of 1800

    • How mental health service systems are organized may affect the rate of acute admissions to specialized care: Report from a natural experiment involving 5338 admissions 

      Myklebust, Lars Henrik Ryther; Sørgaard, Knut W.; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-10)
      Objectives: Studies on the dynamics between service organization and acute admissions to psychiatric specialized care have given ambiguous results. We studied the effect of several variables, including service organization, coercion, and patient characteristics on the rate of acute admissions to psychiatric specialist services. In a natural experiment-like study in Norway, we compared a ...

    • The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort 

      Ness, Nora; Andersen, Sigve; Khanehkenari, Mehrdad Rakaee; Nordbakken, Cecilie V.; Valkov, Andre; Paulsen, Erna-Elise; Nordby, Yngve; Bremnes, Roy M.; Dønnem, Tom; Busund, Lill-Tove; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-01)
      Programmed cell death protein 1 (PD-1) and its ligand Programmed death ligand 1 (PD-L1) have gained massive attention in cancer research due to recent availability and their targeted antitumor effects. Their role in prostate cancer is still undetermined. We constructed tissue microarrays from prostatectomy specimens from 535 prostate cancer patients. Following validation of antibodies, ...

    • Growing up with chronic arthritis: the confusing matter of classification 

      Nordal, Ellen Berit; Guillaume-Czitrom, Severine; Sibilia, Jean (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-09)
      Disease classification in rheumatology is a matter of debate, in paediatrics between International League Against Rheumatism (ILAR) classification ‘pros and cons’, as well as between paediatric and adult rheumatologists. Indeed, there is no consensus yet about how we should name the disease of adults with juvenile idiopathic arthritis (JIA) in childhood. The non-concordance of adult and paediatric ...

    • mHealth technologies for chronic disease prevention and management 

      Laranjo, Liliana; Lau, Annie Y.S.; Oldenburg, B.; Gabarron, Elia; O'Neill, A.; Chan, S.; Coiera, E. (Research report; Forskningsrapport, 2015-12)
      Aims and background: The aim of this rapid review is to examine the evidence relating to the benefits, uptake and operationalisation of mHealth technologies for chronic disease management and prevention. In a context of rapidly emerging technologies, it is important to understand what evidence is available to inform policy interventions designed to integrate technology for health service delivery, ...

    • Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci 

      Cavanagh, Jorunn Pauline; Wolden, Runa; Heise, Philipp; Esaiassen, Eirin; Klingenberg, Claus; Aarag, Elizabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-07)
      The primary aim of this study was to determine antimicrobial resistance in coagulase-negative staphylococci (CoNS) from healthy adults in the community. Healthy adults (n = 114) were swabbed on six body sites; both armpits, both knee pits and both sides of the groin. Species determination was performed using Matrix Assisted Laser Desorption Ionization – Time of Flight (MALDI-TOF) and susceptibility ...

    • Elevated blood pressure is not associated with accelerated glomerular filtration rate decline in the general non-diabetic middle-aged population 

      Eriksen, Bjørn Odvar; Stefansson, Vidar Tor Nyborg; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Schei, Jørgen; Solbu, Marit Dahl; Wilsgaard, Tom; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-14)
      Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated blood pressure (BP) was associated with accelerated GFR decline in the general population. The study ...

    • Perforator-guided drug injection at the point of nerve entrapment 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-14)
      Letter to the Editor

    • Perforator-guided drug injection in the treatment of abdominal wall pain 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-25)
      Background. Pain from the abdominal wall can be caused by nerve entrapment, a condition called abdominal cutaneous nerve entrapment syndrome (ACNES). As an alternative to surgery, ACNES may be treated with injection of local anesthetics, corticosteroids, or botulinum toxin at the point of maximal pain. Method. The point of maximal pain was marked on the abdominal skin. Using color Doppler ultrasound, ...

    • Reply: Form Stability of the Style 410 Implant: Definitions, Conjectures, and the Rest of the Story 

      Weum, Sven Magne; Weerd, Louis de; Kristiansen, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)

    • The Sensate Medial Dorsal Intercostal Artery Perforator Flap as an Option for Treatment of Dorsal Cervicothoracic Midline Defects 

      Weum, Sven Magne; De Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Letter to the Editor

    • The butterfly design as an alternative to the "double-A" bilateral flaps for the treatment of sacral defects 

      Weum, Sven Magne; De Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-04)
      Letter to the Editor

    • Ambulance helicopter contribution to search and rescue in North Norway 

      Glomseth, Ragnar; Gulbrandsen, Fritz I.; Fredriksen, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-13)
      Background: Search and rescue (SAR) operations constitute a significant proportion of Norwegian ambulance helicopter missions, and they may limit the service’s capacity for medical operations. We compared the relative contribution of the different helicopter resources using a common definition of SAR-operation in order to investigate how the SAR workload had changed over the last years. Methods: We ...

    • Detection of Perforators Using Smartphone Thermal Imaging 

      Weum, Sven; Lott, Alexander; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11)
      Letter to the Editor

    • Ultrasound of Small Nerves and Perforator-Guided Treatment of ACNES 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-26)
      Letter to Editor

    • CPR knowledge and attitude to performing bystander CPR among secondary school students in Norway 

      Kanstad, Bjørn Knævelsrud; Nilsen, S. Aa.; Fredriksen, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-04-13)
      Background:<br>Early bystander cardiopulmonary resuscitation (CPR) is essential for survival from out-of-hospital cardiac arrest (OHCA). Young people are potentially important bystander CPR providers, as basic life support (BLS) training can be distributed widely as part of the school curriculum.<br> Methods:<br>Questionnaires were distributed to nine secondary schools in North Norway, and 376 ...

    • Physical examination tests of the shoulder: a systematic review and meta-analysis of diagnostic test performance 

      Gismervik, Sigmund Østgård; Drogset, Jon Olav; Granviken, Fredrik; Rø, Magne; Leivseth, Gunnar (Peer reviewed; Journal article; Tidsskriftsartikkel, 2017-01-25)
      Background: Physical examination tests of the shoulder (PETS) are clinical examination maneuvers designed to aid the assessment of shoulder complaints. Despite more than 180 PETS described in the literature, evidence of their validity and usefulness in diagnosing the shoulder is questioned. Methods: This meta-analysis aims to use diagnostic odds ratio (DOR) to evaluate how much PETS shift ...

    • The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival 

      Kilvær, Thomas Karsten; Paulsen, Erna-Elise; Rakaee, Mehrdad; Al-Saad, Samer; Johansen Maurseth, Ramona; Al-Shibli, Khalid; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-07)
      background: Operable non-small cell lung cancer (NSCLC) patients whose tumours have spread to regional or central lymph nodes at the time of diagnosis have dismal prognoses compared with those who have limited disease. The current TNM staging system for NSCLC poorly distinguishes patients with lymph-node metastases who will succumb to, and those who will eventually be cured from, their disease. ...

    • The epidemiology of post-traumatic stress disorder in Norway: trauma characteristics and pre-existing psychiatric disorders 

      Lassemo, Eva Irene Samant; Sandanger, Inger; Nygård, Jan Franz; Sørgaard, Knut W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-18)
      Purpose: The prevalence of PTSD differs by gender. Pre-existing psychiatric disorders and different traumas experienced by men and women may explain this. The aims of this study were to assess (1) incidence and prevalence of exposure to traumatic events and PTSD, (2) the effect of pre-existing psychiatric disorders prior to trauma on the risk for PTSD, and (3) the effect the characteristics of trauma ...

    • The family experiences of in-hospital care questionnaire in severe traumatic brain injury (FECQ-TBI): a validation study 

      Anke, Audny; Manskow, Unn Sollid; Friborg, Oddgeir; Røe, Cecilie; Arntzen, Cathrine (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-28)
      Background: Family members are important for support and care of their close relative after severe traumas, and their experiences are vital health care quality indicators. The objective was to describe the development of the Family Experiences of in-hospital Care Questionnaire for family members of patients with severe Traumatic Brain Injury (FECQTBI), and to evaluate its psychometric properties and ...

    • Development of a feasible and responsive ultrasound inflammation score for rheumatoid arthritis through a data-driven approach 

      Aga, Anna-Birgitte; Hammer, Hilde Berner; Olsen, Inge Christoffer; Uhlig, Till; Kvien, Tore Kristian; Heijde, Desirée van der; Fremstad, Hallvard; Madland, Tor Magne; Lexberg, Åse; Haukeland, Hilde; Rødevand, Erik; Høili, Christian; Stray, Hilde; Noraas, Anne Lindtner; Hansen, Inger Johanne Widding; Bakland, Gunnstein; Lillegraven, Siri; Lie, Elisabeth; Haavardsholm, Espen A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-16)
      Objective: To develop and validate a responsive and feasible ultrasound inflammation score for rheumatoid arthritis (RA). Methods: We used data from cohorts of early RA (development) and established RA starting/switching biologic therapy (validation). 4 tendons and 36 joints were examined by a grey scale (GSUS) and power Doppler semiquantitative ultrasound (PDUS) scoring system (full score). ...