Viser treff 741-760 av 1800

    • Anal Sphincter Length as Determined by 3-Dimensional Endoanal Ultrasound and Anal Manometry: A Study in Healthy Nulliparous Women 

      Norderval, Stig; Pedersen, Torunn; Collinson, Rowan J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-23)
      <i>Objectives</i> - The normal female external anal sphincter (EAS) is shorter anteriorly than laterally and posteriorly. Furthermore, the thickness of the very proximal part of the circular EAS is thinner than 50% of the lateral and posterior EAS thickness. The extent of these features is not fully explored. The aim of this prospective study was to assess the normal anal sphincter with 3‐dimensional ...
    • Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice 

      Tzellos, Thrasyvoulos; Zouboulis, Christos C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-18)
      Hidradenitis suppurativa (HS) is a chronic, recurrent skin inflammatory disease associated with a variety of comorbidities, like reduced quality of life, metabolic syndrome, sexual dysfunction, working disability, axial spondyloarthritis, inflammatory bowel disease, depression, and anxiety. Like psoriasis, HS patients have been found to have higher risk of cardiovascular death and suicide risk. ...
    • Effect of adiposity on differences in carotid plaque burden in studies conducted in Norway and Russia: a cross-sectional analysis of two populations at very different risk of cardiovascular mortality 

      Imahori, Yume; Frost, Chris; Mathiesen, Ellisiv B.; Ryabikov, Andrey; Kudryavtsev, Alexander V; Malyutina, Sofia; Kornev, Michael; Hughes, Alun D; Hopstock, Laila Arnesdatter; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)
      <i>Objectives</i> - Large differences exist in the burden of cardiovascular disease (CVD) between Russia and Western European countries including Norway. Obesity prevalence may contribute to the differences. We investigated whether difference in the level of adiposity, assessed using body mass index and waist-to-hip ratio(WHR), could explain intercountry differences in the burden of carotid plaque, ...
    • Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty 

      Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-22)
      <p><i>Context - </i>Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement this method. Furthermore, previous studies have not explored the predictive value of endocrine profiling to determine female puberty onset. <p><i>Objective - </i>To ...
    • Hip fracture treatment in Norway deviation from evidence-based treatment guidelines: data from the Norwegian Hip Fracture Register, 2014 to 2018 

      Kjærvik, Cato; Stensland, Eva; Byhring, Hanne Sigrun; Gjertsen, Jan-Erik; Dybvik, Eva; Søreide, Odd (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-14)
      <i>Aims</i> - The aim of this study was to describe variation in hip fracture treatment in Norway expressed as adherence to international and national evidence-based treatment guidelines, to study factors influencing deviation from guidelines, and to analyze consequences of non-adherence.<p> <p><i>Methods</i> - International and national guidelines were identified and treatment recommendations ...
    • Prothrombotic genotypes and risk of major bleeding in patients with incident venous thromboembolism 

      Johnsen, Håkon Sandbukt; Bjøri, Esben; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-22)
      <i>Background</i> - Genotypes associated with venous thromboembolism (VTE) may protect against bleeding due to a hypercoagulable state. Whether the risk of major bleeding is reduced in parallel with an increasing number of prothrombotic genotypes during anticoagulant treatment in VTE remains unknown.<p> <p><i>Objectives</i> - To investigate the association between multiple prothrombotic genotypes ...
    • Residual Corticosteroid Production in Autoimmune Addison Disease 

      Sævik, Åse Bjorvatn; Åkerman, Anna-Karin; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Høybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Valland, Susanna Fonneland; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Bensing, Sophie; Øksnes, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-11)
      <i>Context</i> - Contrary to current dogma, growing evidence suggests that some patients with autoimmune Addison disease (AAD) produce corticosteroids even years after diagnosis.<p> <p><i>Objective</i> - To determine frequencies and clinical features of residual corticosteroid production in patients with AAD.<p> <p><i>Design</i> - Two-staged, cross-sectional clinical study in 17 centers (Norway, ...
    • Transcriptional signatures that define ulcerative colitis in remission 

      Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Sørbye, Sveinung; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-23)
      <i>Background</i> - This study addresses whether existing specific transcriptional profiles can improve and support the current status of the definition of ulcerative colitis (UC) remission apart from the existing endoscopic, histologic, and laboratory scoring systems. For that purpose, a well-stratified UC patient population in remission was compared to active UC and control patients and was ...
    • Uveitis in Juvenile Idiopathic Arthritis 18-Year Outcome in the Population-based Nordic Cohort Study 

      Rypdal, Veronika Gjertsen; Glerup, Mia; Songstad, Nils Tomas; Bertelsen, Geir; Christoffersen, Terje; Arnstad, Ellen D.; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Ekelund, Maria; Peltoniemi, Suvi; Toftedal, Peter; Nielsen, Susan; Leinonen, Sanna; Bangsgaard, Regitze; Nielsen, Rasmus; Rygg, Marite; Nordal, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-28)
      <i>Purpose</i> - To assess the long-term outcome of uveitis in juvenile idiopathic arthritis (JIA).<p> <p><i>Design</i> - Population-based, multicenter, prospective JIA cohort, with a cross-sectional assessment of JIA-associated uveitis (JIA-U) 18 years after the onset of JIA.<p> <p><i>Participants</i> - A total of 434 patients with JIA, of whom 96 had uveitis, from defined geographic areas of ...
    • Revisiting the radiographic assessment of osteoporosis-Osteopenia in children 0-2 years of age. A systematic review 

      Rosendahl, Karen; Lundestad, Anette; Bjørlykke, John Asle; Lein, Regina Küfner; Angenete, Oskar W; Augdal, Thomas Angell; Müller, Lil-Sofie Ording; Jaramillo, Diego (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-02)
      <i>Background</i> - Imaging for osteoporosis has two major aims, first, to identify the presence of low bone mass (osteopenia), and second, to quantify bone mass using semiquantitative (conventional radiography) or quantitative (densitometry) methods. In young children, densitometry is hampered by the lack of reference values, and high-quality radiographs still play a role although the evaluation ...
    • Prevalence of temporomandibular disorder in children and adolescents with juvenile idiopathic arthritis – a Norwegian cross- sectional multicentre study 

      Fischer, Johannes Maria; Skeie, Marit Slåttelid; Rosendahl, Karen; Tylleskär, Karin; Lie, Stein Atle; Shi, Xie-Qi; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet; Halbig, Josefine Mareile; Marti, Larissa von Wangenheim; Rygg, Marite; Frid, Paula; Stoustrup, Peter; Rosén, Annika (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-13)
      <i>Background</i> - Children and adolescents with juvenile idiopathic arthritis (JIA) may suffer pain from temporomandibular disorder (TMD). Still, routines for the assessment of temporomandibular joint (TMJ) pain in health and dental care are lacking. The aims of this study were to examine the prevalence of TMD in children and adolescents with JIA compared to their healthy peers and to investigate ...
    • Whole-body magnetic resonance imaging in children – how and why? A systematic review 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Lein, Regina Küfner; Rosendahl, Karen; Avenarius, Derk; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
      Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free ...
    • Qualitative Evaluations of mHealth Interventions: Current Gaps and Future Directions 

      Bradway, Meghan; Leibowitz, Kari; Garrison, Kathleen A.; Howe, Lauren; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Psycho-social factors are often addressed in behavioral health studies. While the purpose of many mHealth interventions is to facilitate behavior change, the focus is more prominently on the functionality and usability of the technology and less on the psycho-social factors that contribute to behavior change. Here we aim to identify the extent to which mHealth interventions for patient self- management ...
    • Levels of mental distress over 18 years after entering treatment for substance use disorders: A longitudinal cohort study 

      Hjemsæter, Arne Jan; Bramness, Jørgen Gustav; Drake, Robert; Skeie, Ivar; Monsbakken, Bent Berntsen; Saltyte Benth, Jurate; Landheim, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-17)
      <i>Aims:</i> The aims were to investigate whether baseline characteristics and problematic substance use were related to change in mental distress over time in patients with substance use disorders during an 18-year period.<p> <p><i>Method:</i> This was a prospective, longitudinal study of patients followed for 18 years after entering specialised treatment for substance use disorders. A sample ...
    • Centralizing a national pancreatoduodenectomy service: striking the right balance 

      Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-07)
      <i>Background</i> - Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher‐volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus on the optimal balance has not yet been reached. This observational study presents a volume–outcome analysis of a complete national cohort in a health system with ...
    • User-centred Design with a Remote Approach: Experiences from the Chronic Pain Project 

      Smaradottir, Berglind; Bellika, Johan Gustav; Fredeng, Aina; Fagerlund, Asbjørn Johansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      User-centred design involves end-users or user groups during all the parts of the development process. The research project Chronic Pain aims to develop a shared decision making application for patients and physicians, addressing individually adapted pain treatment. The project employs a user-centred design process, and in middle of it, Covid-19 pandemic social distancing restrictions were imposed. ...
    • ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial 

      Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika; Becker, Richard C; Bertilson, Maria; Budaj, Andrzej; Cornel, Jan H; Himmelmann, Anders; James, Stefan K; Siegbahn, Agneta; Storey, Robert F; Kontny, Frederic; Aukrust, Pål; Wallentin, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-29)
      <p><i>Background and aims - </i>Activated leukocyte cell adhesion molecule (ALCAM) is upregulated during inflammation and involved in transmigration of leukocytes and T-cell activation. We hypothesized that ALCAM might be associated with recurrent events in patients with acute coronary syndromes (ACS). <p><i>Methods - </i>ALCAM was measured in serum obtained on admission, at discharge, 1 month and ...
    • Comparative effectiveness of microdecompression alone vs decompression plus instrumented fusion in lumbar degenerative spondylolisthesis 

      Austevoll, Ivar Magne; Gjestad, Rolf; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Hermansen, Erland; Rekeland, Frode; Indrekvam, Kari; Hellum, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)
      <i>Importance</i> - Conflicting evidence and large practice variation are present in the surgical treatment of degenerative spondylolisthesis. More than 90% of surgical procedures in the United States include instrumented fusion compared with 50% or less in other countries.<p> <p><i>Objective</i> - To evaluate whether the effectiveness of microdecompression alone is noninferior to decompression ...
    • The prevalence of hereditary neuromuscular disorders in Northern Norway 

      Müller, Kai Ivar; Van Ghelue, Marijke; Lund, Irene; Jonsrud, Christoffer; Arntzen, Kjell Arne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-13)
      <i>Aim</i> - To investigate the point prevalence of hereditary neuromuscular disorders on January 1, 2020 in Northern Norway.<p> <p><i>Methods</i> - From January 1, 1999, until January 1, 2020, we screened medical and genetic hospital records in Northern Norway for hereditary neuromuscular disorders.<p> <p><i>Results</i> - We identified 542 patients with a hereditary neuromuscular disorder ...
    • The total prevalence of diagnosed diabetes and the quality of diabetes care for the adult population in Salten, Norway 

      Slåtsve, Kristina Barbara; Claudi, Tor; Lappegård, Knut Tore; Jenum, Anne Karen; Larsen, Marthe; Cooper, John; Sandberg, Sverre; Berg, Tore Julsrud (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-27)
      <p><i>Objective:</i> To assess the total prevalence of types 1 and 2 diabetes and to describe and compare cardiovascular risk factors, vascular complications and the quality of diabetes care in adults with types 1 and 2 diabetes in Salten, Norway. <p><i>Research design and methods:</i> Cross-sectional study including all patients with diagnosed diabetes in primary and specialist care in Salten, ...