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dc.contributor.authorNeufcourt, Lola
dc.contributor.authorCastagne, Raphaele
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorGrimsgaard, Sameline
dc.contributor.authorChadeau-Hyam, Marc
dc.contributor.authorVuckovic, Dragana
dc.contributor.authorUgarteche-Perez, Ainhoa
dc.contributor.authorFarbu, Erlend Hoftun
dc.contributor.authorSandanger, Torkjel Manning
dc.contributor.authorDelpierre, Cyrille
dc.contributor.authorKelly-Irving, Michelle
dc.date.accessioned2023-12-19T08:56:25Z
dc.date.available2023-12-19T08:56:25Z
dc.date.issued2023-11-20
dc.description.abstractBackground: Social-to-biological processes is one set of mechanisms underlying the relationship between social position and health. However, very few studies have focused on the relationship between social factors and biology at multiple time points. This work investigates the relationship between education and the dynamic changes in a composite Biological Health Score (BHS) using two time points seven years apart in a Norwegian adult population.<p> <p>Methods: We used data from individuals aged 30 years and above who participated in Tromsø6 (2007–2008) and Tromsø7 (2015–2016) (n = 8117). BHS was defined using ten biomarkers measured from blood samples and representing three physiological systems (cardiovascular, metabolic, inflammatory). The higher the BHS, the poorer the health status. <p>Findings: Linear regression models carried out on BHS revealed a strong educational gradient at two distinct time points but also over time. People with lower educational attainment were at higher risk of poor biological health at a given time point (β<sub>low education Tromsø</sub>6=0.30 [95 %-CI=0.18–0.43] and β<sub>low education Tromsø</sub>7=0.30 [95 %-CI=0.17–0.42]). They also presented higher longitudinal BHS compared to people with higher education (β<sub>low education</sub> = 0.89 [95 %-CI=0.56–1.23]). Certain biomarkers related to the cardiovascular system and the metabolic system were strongly socially distributed, even after adjustment for sex, age, health behaviours and body mass index. <p>Conclusion: This longitudinal analysis highlights that participants with lower education had their biological health deteriorated to a greater extent over time compared to people with higher education. Our findings provide added evidence of the biological embodiment of social position, particularly with respect to dynamic aspects for which little evidence exists.en_US
dc.identifier.citationNeufcourt, Castagne, Wilsgaard, Grimsgaard, Chadeau-Hyam, Vuckovic, Ugarteche-Perez, Farbu, Sandanger, Delpierre, Kelly-Irving. Educational patterning in biological health seven years apart: Findings from the Tromsø Study. Psychoneuroendocrinology. 2023en_US
dc.identifier.cristinIDFRIDAID 2202402
dc.identifier.doi10.1016/j.psyneuen.2023.106670
dc.identifier.issn0306-4530
dc.identifier.issn1873-3360
dc.identifier.urihttps://hdl.handle.net/10037/32159
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalPsychoneuroendocrinology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleEducational patterning in biological health seven years apart: Findings from the Tromsø Studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)