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dc.contributor.authorTuomi, Anna-Kaisa
dc.contributor.authorRebane, Katariina
dc.contributor.authorArnstad, Ellen Dalen
dc.contributor.authorBerntson, Lillemor
dc.contributor.authorFasth, Anders
dc.contributor.authorGlerup, Mia
dc.contributor.authorHerlin, Troels
dc.contributor.authorKautiainen, Hannu
dc.contributor.authorNordal, Ellen Berit
dc.contributor.authorPeltoniemi, Suvi
dc.contributor.authorRygg, Marite
dc.contributor.authorRypdal, Veronika Gjertsen
dc.contributor.authorZak, Marek
dc.contributor.authorAalto, Kristiina
dc.date.accessioned2024-09-05T08:28:52Z
dc.date.available2024-09-05T08:28:52Z
dc.date.issued2024-02-02
dc.description.abstractBackground There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients with juvenile idiopathic arthritis (JIA). Our aim was to investigate the impact of BMI on health-related quality of life (HRQoL) measured with a 36-Item Short Form Survey (SF-36), disease activity, and disability in young adults with JIA.<p> <p>Methods This study is a part of the population-based Nordic JIA cohort study. All newly diagnosed patients with JIA were recruited consecutively between 1997–2000 in specific regions in the Nordic countries. Patients in this substudy were enrolled from 434 patients who attended their 18-year follow-up visit. Patients were classified according to the World Health Organization (WHO) into four groups based on their BMI. HRQoL, disease characteristics, disability, fatigue, sleep quality, physical activity, pain, comorbidities, and social status were assessed. <p>Results Three hundred fifty-five patients from the original study cohort were enrolled in this study and 72% of them were female. Mean age was 23.9 (±SD 4.4) years. A significant relationship was found between the JIA categories and BMI groups (p=0.014). A significant relationship was also found between BMI and disease activity scores (DAS28) (p=0.028), disability (p<0.001), pain (p=0.013), fatigue (p=0.035), and sleep quality (p=0.044). Moreover, a significant relationship between BMI and HRQoL regarding bodily pain (p=0.010) and general health (p=0.048) was revealed when adjusted for sex, age, and JIA subtype. <p>Conclusion We discovered that BMI was significantly related to HRQoL, disease activity, and disability. BMI deserves more attention considering the treatment options and outcome of JIA in young adults.en_US
dc.identifier.citationTuomi, Rebane, Arnstad, Berntson, Fasth, Glerup, Herlin, Kautiainen, Nordal, Peltoniemi, Rygg, Rypdal, Zak, Aalto. Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis. Pediatric Rheumatology. 2024;22(1)en_US
dc.identifier.cristinIDFRIDAID 2248734
dc.identifier.doi10.1186/s12969-023-00931-7
dc.identifier.issn1546-0096
dc.identifier.urihttps://hdl.handle.net/10037/34520
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalPediatric Rheumatology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2024 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleBody mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritisen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)